Overcoming immune resistance in advanced esophageal squamous cell carcinoma with recombinant human adenovirus type 5 by impacting the immune microenvironment: a case report [0.03%]
重组人腺病毒5型通过影响免疫微环境克服食管鳞状细胞癌晚期的免疫抵抗：一例报告
Zhongting Wang,Junfeng Hong,Huiping Wu et al.
Zhongting Wang et al.
Advanced esophageal squamous cell carcinoma (ESCC) has a poor prognosis. Chemotherapy combined with immune checkpoint inhibitors is a feasible treatment, but effective treatment modalities need to be explored for its immune resistance. H101...
PD-L1 deficiency exacerbates colitis severity by remodeling gut microbiota in inflammatory bowel disease [0.03%]
pd-l1缺乏通过重塑炎症性肠病肠道微生物群加重结肠炎严重程度
Yixian Ma,Jinshan Suo,Siqi Sheng et al.
Yixian Ma et al.
Background: Inflammatory bowel disease (IBD) is a chronic autoimmune disorder driven by gut microbiota dysbiosis. As an essential immune checkpoint, Programmed death-ligand 1 (PD-L1) has been implicated in modulating gut ...
Astrocyte-microglia crosstalk in subarachnoid hemorrhage: mechanisms and treatments [0.03%]
蛛网膜下腔出血中星形胶质细胞-小胶质细胞相互作用：机制与治疗
Kaibo Yu,Ding Wang,Wenhua Yu
Kaibo Yu
Subarachnoid hemorrhage (SAH) is a frequently encountered critical emergency characterized by the rupturing of an unhealthy blood vessel, resulting in high mortality and disability rates. Alterations in the neurovascular unit (NVU) are clos...
Chronic inducible urticaria - having more than one is common and clinically relevant [0.03%]
慢性发作性荨麻疹——同时患有多种类型的情况很常见且具有临床意义
Marina Lebedkina,Elena Kovalkova,Gerelma Andrenova et al.
Marina Lebedkina et al.
Background: Chronic inducible urticaria (CIndU) is characterized by wheals and/or angioedema (AE) for 6 weeks or more in response to specific and definite triggers. Individual patients can have more than one type of CIndU...
LncRNA NEAT1 promotes epithelial-mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis [0.03%]
长链非编码RNA NEAT1通过miR-199-3p/PAK4轴促进鼻息肉上皮间质转化
Shuman Li,Yu Jiang,Yalan Zhang et al.
Shuman Li et al.
Background and purpose: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition marked by high recurrence and limited therapeutic efficacy. This study investigates the role of long non-cod...
A novel nomogram for survival prediction in renal cell carcinoma patients with brain metastases: an analysis of the SEER database [0.03%]
基于SEER数据库的I型肾细胞癌脑转移患者预后预测新列线图模型研究
Fei Wang,Xihao Wang,Zhigang Feng et al.
Fei Wang et al.
Background: Existing research on the development of prognostic models for renal cell carcinoma (RCC) patients with brain metastases (BM) remains limited. This study aimed to develop a prognostic prediction model for RCC p...
Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of TSG-6 [0.03%]
骨髓间充质干细胞衍生的外泌体通过递送TSG-6抑制肠上皮细胞焦亡缓解小鼠DSS诱导的炎症性肠病
Bihua Wu,Shuangyan Su,Xianyu Wang et al.
Bihua Wu et al.
Background: Inflammatory bowel disease (IBD), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to the limitations of current treatments, including dr...
Correction: Development of a subunit vaccine against the cholangiocarcinoma causing Opisthorchis viverrini: a computational approach [0.03%]
订正：一种针对引起胆管癌的猫肝吸虫的亚单元疫苗的发展：一种计算方法
Mohibullah Shah,Farva Sitara,Asifa Sarfraz et al.
Mohibullah Shah et al.
[This corrects the article DOI: 10.3389/fimmu.2024.1281544.]. Keywords: Opisthorchis viverrini; cholangiocar...
Published Erratum
Frontiers in immunology. 2025 Jun 30:16:1638914. DOI:10.3389/fimmu.2025.1638914 2025
Beyond proofreading: POLD1 mutations as dynamic orchestrators of genomic instability and immune evasion in cancer [0.03%]
超越校对：POLD1突变作为癌症基因组不稳定性和免疫逃避的动态调控因子
Huiqing Chen,Jiayu Wei,Qi Tang et al.
Huiqing Chen et al.
DNA polymerase delta (Pol δ) is a cornerstone of genomic stability, orchestrating DNA replication and repair through its catalytic subunit, POLD1. This subunit's 3'-5' exonuclease domain proofreads replication errors, ensuring fidelity. Ho...
Understanding the microbiome in autologous haemopoietic stem cell transplant for multiple sclerosis [0.03%]
自体造血干细胞移植治疗多发性硬化症中的微生态认识研究
Jun Yin,Nadeem O Kaakoush,Jennifer Massey et al.
Jun Yin et al.
Background: MS is a chronic inflammatory and degenerative disease of the central nervous system (CNS) resulting in neurological deficits associated with physical and/or cognitive disability. The gut microbiome can interac...