A machine learning approach to a nine-SNP immunogenetic score for prognostic stratification in cervical cancer [0.03%]
宫颈癌预后分层的九个SNP免疫遗传评分的机器学习方法
Sabrina Zidi,Besma Yacoubi-Loueslati,Boutheina Ben Abdelmoumen Mardassi et al.
Sabrina Zidi et al.
Background: While human papillomavirus (HPV) is the primary driver of cervical cancer (CC), host immune-related genetic variations are thought to influence clinical heterogeneity. The role of combined immune-related singl...
Comprehensive analysis of mitophagy-related genes reveals prognostic signatures in breast cancer: based on immune landscapes and treatment target predict [0.03%]
线粒体自噬相关基因的全面分析揭示了乳腺癌中的预后标志物：基于免疫图谱和治疗靶点预测
Hejia Zhao,Wanying Zhang,Yiheng Du et al.
Hejia Zhao et al.
Background: Breast cancer (BC) is a common malignant tumor with high incidence and mortality rates. Mitophagy refers to a selective form of autophagy that is believed to be closely related to the occurrence and progressio...
Glycosaminoglycan binding to soluble CX3CL1 impacts monocyte migration in vitro [0.03%]
可溶性CX3CL1与糖胺聚糖结合影响单核细胞体外迁移
Maria Ennemoser,Paula Peinsipp,Tihana Novak et al.
Maria Ennemoser et al.
Introduction: In addition to providing shear-resistant cell-cell adhesion in its natural membrane-bound form, the soluble variant of CX3CL1 (or fractalkine) promotes strong cell migration through signaling via its unique ...
Therapeutic drug monitoring of adalimumab in hidradenitis suppurativa: a prospective observational study [0.03%]
阿达利姆单抗治疗毛囊炎的药物浓度监测：一项前瞻性观察研究
Stella X Chen,Bruna Galvao de O Wafae,Sydney Look-Why et al.
Stella X Chen et al.
Background: Adalimumab (ADA) is an effective treatment for moderate to severe hidradenitis suppurativa (HS). However, nearly half of patients receiving the standard dose may lose response. ...
Observational Study
Frontiers in immunology. 2026 Feb 5:17:1760206. DOI:10.3389/fimmu.2026.1760206 2026
Case Report: Upadacitinib for SAPHO syndrome with biologics-induced paradoxical manifestation and Hyperimmunoglobulinemia E [0.03%]
案例报告：生物制剂诱导的矛盾表现和高免疫球蛋白E综合征伴有的SAPHO综合征的Upadacitinib治疗
Yuxi Liu,Di Jin,Wen Li et al.
Yuxi Liu et al.
Background: SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare autoinflammatory disease. Paradoxical reactions and immune deviation following biologic therapy are occasionally observed in c...
Association between the C-reactive protein-albumin-lymphocyte index and cardiovascular incidence and mortality among patients with chronic kidney disease: a prospective study [0.03%]
C反应蛋白-白蛋白-淋巴细胞指数与慢性肾脏病患者的心血管事件和死亡风险的相关性：一项前瞻性研究
Chen Jiang,Qi Zhou,Jian Feng et al.
Chen Jiang et al.
Background and aim: The recently developed C-reactive protein-to-albumin-to-lymphocyte (CALLY) index represents a novel composite biomarker that simultaneously reflects inflammatory status, immune competence, and nutritio...
Pre-antigenic regulatory signals in osteoarthritis: modulators of dendritic cell activation and joint immune balance [0.03%]
骨关节炎中的抗原免疫调节信号：树突状细胞活化和关节免疫平衡的调控因素
Jiabao Liang,Andrew Mark Jackson
Jiabao Liang
Osteoarthritis (OA) is now recognized as an immune-metabolic disorder rather than a simple wear-and-tear disease. Dendritic cells (DCs) in the synovium and subchondral bone link mechanical, biochemical, and metabolic stress to immune imbala...
Ferroptosis and Alzheimer's disease: a new insight into neurodegeneration [0.03%]
铁死亡与阿尔茨海默病：神经退行性病变的新视角
Youfang Quan,Hongwei Liu,Minheng Zhang et al.
Youfang Quan et al.
Alzheimer's disease (AD), a chronic and progressive neurodegenerative disorder, poses a significant threat to the health of the aging population. The pathological hallmarks of AD include the accumulation of amyloid-β (Aβ) plaques and neur...
Abatacept treatment shows a modulating effect on Treg subsets in LRBA-deficient patients [0.03%]
阿巴西普治疗对LRBA缺陷患者Tregs亚群的调节作用显示了其疗效
Sabine Donhauser,Emilia Salzmann-Manrique,Leon Maximilian Lueck et al.
Sabine Donhauser et al.
There has been tremendous progress in the understanding of subsets of regulatory T cells (Tregs). However, despite their theoretical importance, Treg subsets are not routinely analyzed in patients with immune dysregulation over the course o...
2',4'-dihydroxychalcone alleviates inflammatory bowel disease by inhibiting NLRP3 inflammasome and modulating gut microbiota [0.03%]
Guohui Zhang,Yixin Yao,Zhongyu Zhang et al.
Guohui Zhang et al.
Introduction: Abrus cantoniensis Hance (ACH), an edible traditional Chinese medicinal herb, has significant anti-inflammatory activity. However, there is limited research on the molecular targets of its active ingredients...