Integrated single-cell and bulk RNA sequencing analyses identify a myeloid state-related gene signature for molecular subtyping in stomach adenocarcinoma [0.03%]
整合单细胞和批量RNA测序分析,识别胃腺癌分子分型的髓样状态相关基因签名
Ruinan Li,Bohong Wei,Bin Sun et al.
Ruinan Li et al.
Purpose: Stomach adenocarcinoma (STAD) is characterized by significant heterogeneity, within which myeloid cells play crucial yet incompletely understood roles. The relationship between the functional states of myeloid ce...
Licensed and investigational TLR4 agonists as vaccine adjuvants: structural basis, clinical progress, and future directions [0.03%]
TLR4激动剂疫苗佐剂的研发进展及未来方向:结构基础与临床应用
Jiasheng Zhou,Bo Liu,Qiao Yang et al.
Jiasheng Zhou et al.
The development of innovative vaccine platforms, including protein subunit and nucleic acid vaccines, has advanced rapidly and established new technical paradigms for infectious disease prophylaxis. Nonetheless, many next-generation vaccine...
Gut microbiota derived indoles are altered and associate with immune activation in moderate and severe carotid stenosis [0.03%]
中重度颈动脉狭窄患者肠道微生物群产生吲哚衍生物的改变及其与免疫激活的关系
Kristine Stø,Karolina Skagen,Vigdis Bjerkeli et al.
Kristine Stø et al.
Background: An imbalance of gut microbiota, their metabolites as well as inflammatory mediators have been increasingly linked to both atherosclerosis and stroke. However, data on microbiota derived tryptophan and histidin...
Bacillus Calmette-Guérin as adjuvant platform enhances immunogenicity of conserved epitopes from structural proteins of SARS-CoV-2 [0.03%]
卡介苗作为佐剂平台可增强SARS-CoV-2结构蛋白保守表位的免疫原性
Ana de Souza Santos,Leonardo Pereira de Araújo,Diego Jose Belato Orts et al.
Ana de Souza Santos et al.
The development of effective and broadly protective vaccines against SARS-CoV-2 remains a global priority. Conserved epitopes from viral structural proteins (E, M, N, and S) represent promising targets less affected by emerging mutations, w...
Autoimmune thyroiditis and comorbid autoimmune diseases: global research landscape and future directions [0.03%]
自身免疫性甲状腺炎及其共病自身免疫性疾病:全球研究格局与未来方向
Jie Tian,Feng Guo,Hao-Han Rao et al.
Jie Tian et al.
Objective: Autoimmune thyroiditis (AIT) patients frequently present with coexisting autoimmune diseases (ADs), adding complexity to management and outcomes. Although this field has been extensively explored, there is a pa...
Youichi Ogawa,Takuya Sato,Lisa Minai et al.
Youichi Ogawa et al.
The concept of tissue-resident memory T (TRM) cells has fundamentally transformed our understanding of peripheral immune surveillance. Although skin TRM biology has been extensively studied, most investigations have focused on the dermis, w...
The evolving landscape of Staphylococcus aureus immune evasion: a data-driven atlas over two decades [0.03%]
金黄色葡萄球菌免疫逃避的演变景观:二十年来的数据驱动图谱
Yize Fan,Shu Wang,Xingyu Zhu et al.
Yize Fan et al.
Background: Staphylococcus aureus (S. aureus) has emerged as a significant global public health threat, owing to its complex immune evasion strategies. Despite growing research output in this field, a comprehensive, data-...
Correction: AI-driven insights into protein misfolding and innate immunity in neurodegenerative diseases [0.03%]
纠正:人工智能驱动的蛋白质错误折叠和先天免疫在神经退行性疾病中的见解
Hui Xin Deng,Jing Ling Cao,Yao Wu et al.
Hui Xin Deng et al.
[This corrects the article DOI: 10.3389/fimmu.2026.1814357.]. Keywords: artificial intelligence; innate immu...
Published Erratum
Frontiers in immunology. 2026 Jul 14:17:1879874. DOI:10.3389/fimmu.2026.1879874 2026
Blood urea nitrogen-to-albumin ratio predicts mortality in acute graft-versus- host disease after allogeneic stem cell transplantation [0.03%]
血尿素氮/白蛋白比率用于预测allo-HSCT后急性GVHD患者的死亡风险
Gangping Li,Di Zhang,Minghui Li et al.
Gangping Li et al.
Background: Evidence regarding the association between the blood urea nitrogen to albumin ratio (BAR) and clinical outcomes in acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic stem cell transplan...
Perspectives on chronic granulomatous disease: results of a clinician survey [0.03%]
关于慢性肉芽肿病的调查报告:临床医生的观点
Joao Pedro Matias Lopes,Ben Z Katz,Niraj C Patel et al.
Joao Pedro Matias Lopes et al.
Background: Chronic granulomatous disease (CGD) is a primary immune deficiency characterized by neutrophils with an insufficient oxidative burst. Symptoms include infections and inflammatory manifestations affecting the l...