Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report [0.03%]
多线免疫化疗和抗血管生成治疗后晚期肺大细胞神经内分泌癌长期生存的病例报告
Hongming Wang,Shiyan Li,Xiaoyang Liu et al.
Hongming Wang et al.
Background: Pulmonary large-cell neuroendocrine carcinoma (PLCNEC) is a rare and highly aggressive subtype of lung cancer with neuroendocrine features, typically diagnosed at an advanced stage. Its clinical presentation a...
Mitochondrial unfolded protein response in regulatory T cell function: a protective mechanism in immune aging [0.03%]
线粒体未折叠蛋白反应在调节性T细胞功能中的作用：免疫衰老中的保护机制
Lillie Lewis,Deepa Valvi,Roberto Gedaly et al.
Lillie Lewis et al.
Age-related conditions, such as neurodegenerative disease, cancer, and autoimmune disorders, are increasingly recognized as closely linked with the gradual deterioration of the immune system. Regulatory T cells (Tregs) are a small, speciali...
Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women [0.03%]
单细胞RNA测序揭示了恢复期COVID-19孕妇NK细胞功能的下降
Madhuri S Salker,Nor Haslinda Abd Aziz,Natalia Carman Prodan et al.
Madhuri S Salker et al.
Introduction: During gestation the immune system undergoes dramatic remodelling to protect the maternal-fetal dyad from infections whilst also preventing fetal rejection. We investigated how SARS-CoV-2 modifies the immune...
Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3 [0.03%]
短期暴露在高湿度环境通过AQP3引发肠道炎症
Jian Song,Xinhua Huang,Yi Luo et al.
Jian Song et al.
Background: With the increasing greenhouse effect, there is growing concern about the correlation between the humid environment and the incidence of various diseases. A high-humidity environment may cause intestinal infla...
Wenyu Zhang,Xianzong Ma,Wenqing Tian et al.
Wenyu Zhang et al.
Background: Crohn's disease (CD) is a complex and heterogeneous inflammatory disease whose most important feature is immune dysregulation. As a basic cell response, cellular senescence (CS) can regulate the immune respons...
circ-0001875 downregulation is associated with M1 macrophage activation and lung inflammation in severe asthma [0.03%]
circ-0001875低表达与重度哮喘M1型巨噬细胞活化及肺部炎症相关
Gege Liu,Jiahao Cao,Yiyan Lin et al.
Gege Liu et al.
Background: Asthma is a heterogeneous group of diseases. The mechanism by which dysregulated circRNAs affect severe asthma by regulating macrophage polarization remains unclear. ...
Cadonilimab combined with trastuzumab and chemotherapy for HER2-positive gastric cancer with bone marrow metastasis and DIC: a case report and literature review [0.03%]
Cadonilimab联合曲妥珠单抗和化疗治疗HER2阳性胃癌伴骨髓转移及DIC病例报告及文献复习
Meijing Chen,Jiwen Fan,Danyang Zhou et al.
Meijing Chen et al.
Background: Gastric cancer (GC) is one of the most common malignancies worldwide. While bone marrow metastasis (BMM) in GC is extremely rare and often complicated by disseminated intravascular coagulation (DIC), a critica...
Correction: Conversion therapy with TACE, TKIs, and ICIs for unresectable BCLC stage B and C hepatocellular carcinoma [0.03%]
纠正：不可切除BCLC B和C期肝细胞癌的转流疗法（TACE，TKI和ICI）
Zhuoran Wang,Cunzhen Zhang,Jianhua Yin et al.
Zhuoran Wang et al.
[This corrects the article DOI: 10.3389/fimmu.2025.1451965.]. Keywords: TACE; anti-PD-1 antibody; anti-angio...
Published Erratum
Frontiers in immunology. 2025 Jun 30:16:1647890. DOI:10.3389/fimmu.2025.1647890 2025
Case Report: Subcutaneous ofatumumab for patients with immunosuppressant-dependent or ineffective primary membranous nephropathy [0.03%]
病例报告：皮下注射 Ofatumumab 治疗免疫抑制剂依赖或无效的原发性膜性肾病患者
Jie Chen,De-Tian Li,Xin Feng et al.
Jie Chen et al.
CD20 monoclonal antibodies (mAbs), particularly rituximab, have become a preferred treatment for many patients with phospholipase A2 receptor (PLA2R)-related membranous nephropathy (MN). However, some patients either fail to respond to ritu...
Immunopathogenic and clinical implications of advanced tissue analysis in non-tuberculous mycobacterial infections in children [0.03%]
儿童非结核分枝杆菌感染中组织病理分析的免疫病理和临床意义
Maximilian Seidl,Elham Bavafaye Haghighi,Anne Kathrin Lösslein et al.
Maximilian Seidl et al.
Objectives: Infections with non-tuberculous mycobacteria (NTM) in children usually affect the lymph nodes and surrounding tissue. Although the infection is typically self-limiting, it carries a substantial risk of complic...
Observational Study
Frontiers in immunology. 2025 Jun 26:16:1597074. DOI:10.3389/fimmu.2025.1597074 2025