Distinct effects of adjuvants on B cell responses to protein or polysaccharide antigens contained in glycoconjugate vaccines [0.03%]
佐剂对糖缀合疫苗中蛋白质或多糖抗原的B细胞反应的不同影响
Sonia Budroni,Elisa Faenzi,Simona Tavarini et al.
Sonia Budroni et al.
Background: Protein-polysaccharide conjugate vaccines rely on the induction of T-cell-dependent responses that support germinal center (GC) reactions to potentiate the expansion of antigen-specific memory B-cell (MBC) pop...
Editorial: Case reports in autoimmune and autoinflammatory disorders [0.03%]
风信子评论:自身免疫和(auto)炎症性疾病个例报道
Chris Wincup,Augusto Vaglio,Stefano Volpi et al.
Chris Wincup et al.
Editorial: Post-transcriptional modifications in cancer immunity and immunotherapy [0.03%]
述评:癌症免疫和免疫治疗中的转录后修饰
Gaigai Wei,Yufeng Zhou,Tao Yue et al.
Gaigai Wei et al.
Efficacy and safety of obinutuzumab in primary membranous nephropathy: a real-world retrospective study [0.03%]
奥比妥珠单抗治疗原发性膜性肾病的疗效和安全性:一项真实世界回顾性研究
Xi Cheng,Zhen-Feng Zheng,Yan Qi et al.
Xi Cheng et al.
Objective: This study aimed to evaluate the efficacy and safety of obinutuzumab, a novel anti-CD20 monoclonal antibody, in patients with primary membranous nephropathy (pMN). ...
Harriet C Pope,Ana L Chiodetti,Alice Newey et al.
Harriet C Pope et al.
Background: The programmed cell death protein 1 (PDCD1 or PD-1) is a key regulatory immune checkpoint and a major target for therapeutic intervention. In oncology, antibodies blocking the PD-1 pathway are used to activate...
Exploring research trends in cancer immunotherapy via single-cell technologies: a scientometric perspective [0.03%]
基于单细胞技术的肿瘤免疫治疗研究趋势挖掘及科学计量学视角分析
Zhongxun Li,Qi Han,Zimu Huang et al.
Zhongxun Li et al.
Introduction: Cancer immunotherapy has brought new therapeutic hopes for cancer patients, but it is complex in its mechanism of action, and there are significant individual differences, which restricts its wide use. As si...
Curcumin, an active component of turmeric: biological activities, nutritional aspects, immunological, bioavailability, and human health benefits - a comprehensive review [0.03%]
姜黄活性成分 curcumin 的生物、营养、免疫、药代动力学及对人体健康的功效-全面综述
Mohamed T El-Saadony,Ahmed M Saad,Dina Mostafa Mohammed et al.
Mohamed T El-Saadony et al.
Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a naturally occurring polyphenol molecule. It is lipophilic and has demonstrated in vitro and in vivo therapeutic effects through multiple pathways. Extensive studi...
CD68 as a multi-omic prognostic biomarker in digestive system cancers: correlations with tumor-infiltrating immune cells and immune checkpoints [0.03%]
CD68作为消化系统肿瘤预后生物标志物与肿瘤浸润性免疫细胞和免疫检查点的相关性研究
Hui Li,Hui Zhang,Rujiang Dai et al.
Hui Li et al.
Background and objective: CD68 plays a crucial role in promoting phagocytosis. However, its expression level, prognostic value and the correlations with tumor-infiltrating immune cells (TIICs) or common tumor immune check...
Cui Xin,Peiyun Liu,Qianqian Zhan et al.
Cui Xin et al.
T cells are integral to the immune response, with distinct subsets exhibiting specialized functions, a phenomenon well-characterized in helper CD4+ T cells. Recent advancements in single-cell RNA sequencing (scRNA-seq) have facilitated the ...
Combination of αCD4 antibody and retinal antigen injection induces long-term disease control in autoimmune uveitis [0.03%]
αCD4抗体与视网膜抗原联合注射诱导自身免疫性脉络膜视网膜炎长期缓解
Dijie Qiao,Lu Zhang,Yajie Zhong et al.
Dijie Qiao et al.
Introduction: Autoimmune uveitis is a sight-threatening inflammatory eye disease driven by immune dysregulation. We previously introduced a therapeutic strategy involving the in vivo induction of retinal-antigen-specific ...