Transcriptomic mortality signature defines high-risk neonatal sepsis endotype [0.03%]
转录组学死亡标志物定义了高危新生儿败血症亚型
Faris N Al Gharaibeh,Min Huang,James L Wynn et al.
Faris N Al Gharaibeh et al.
Introduction: Neonatal sepsis remains a leading cause of global childhood mortality, yet treatment options are limited. Clinical and biological heterogeneity hinders the development of targeted therapies. Gene-expression ...
A new insight: crosstalk between neutrophil extracellular traps and the gut-liver axis for nonalcoholic fatty liver disease [0.03%]
新见解：中性粒细胞胞外陷阱与肠肝轴在非酒精性脂肪肝病中的相互作用
Jinping Yin,Yanli Zhu,Rongrong Liu et al.
Jinping Yin et al.
Non-alcoholic fatty liver disease (NAFLD) is a widespread chronic liver disorder, affecting nearly a quarter of the global population. It progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hep...
Myeloid Zinc Finger 1: insights into its oncogenic potential, prognostic value, and impact on immune microenvironment across cancers [0.03%]
髓系锌指基因1：其致癌潜能、预后价值及对肿瘤免疫微环境影响的多癌种研究见解
Wenze Tian,Chun Yu,Xin Xu et al.
Wenze Tian et al.
Background: Myeloid Zinc Finger 1 (MZF1) is a zinc finger transcription factor gene that regulates gene expression by recognizing and binding to specific DNA sequences. Preliminary studies have suggested that MZF1 plays a...
The role of ATF3 in precision medicine of brain arteriovenous malformation: based on endothelial cell proliferation [0.03%]
ATF3在脑动静脉畸形精准治疗中的作用：基于内皮细胞增殖的角度
Jiwei Ma,Lei Meng,Jiyu Ji et al.
Jiwei Ma et al.
Background: Brain arteriovenous malformation (BAVM) is a destructive high-flow vascular abnormality that can lead to various cerebral hemodynamic disorders. The incidence of BAVM has risen significantly in recent years, y...
The multifaceted roles of mucins family in lung cancer: from prognostic biomarkers to promising targets [0.03%]
黏蛋白家族在肺癌中的多种作用：从预后生物标志物到有前景的治疗目标
Qinghong Yuan,Sirui Cai,Yuanhang Chang et al.
Qinghong Yuan et al.
Lung cancer remains one of the leading causes of cancer-related deaths worldwide, highlighting the urgent need for enhanced diagnostic and therapeutic strategies. Mucins, a family of glycoproteins crucial for maintaining epithelial integrit...
Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells [0.03%]
用于制造CAR-T细胞的生物功能水凝胶包覆膜以减少T细胞衰竭
Aida López Ruiz,Eric Slaughter,Kartik Bomb et al.
Aida López Ruiz et al.
Introduction: Cell therapies have revolutionized cancer treatment, with chimeric antigen receptor (CAR) T-cell therapies at the forefront for the treatment of hematological cancers. However, current manufacturing protocol...
Exploring the genetic basis of Newcastle disease virus in chickens: a comprehensive review [0.03%]
鸡新城疫病毒的遗传基础研究：综述论文
Haile Berihulay,Wei Luo,Ainong Lao et al.
Haile Berihulay et al.
Newcastle disease (ND) is one of the most serious viral diseases affecting chickens and is caused by Newcastle disease virus (NDV), an avian paramyxovirus serotype-1. The virus contains five structural proteins and two nonstructural protein...
Editorial: Community series in cell network in antitumor immunity of pediatric and adult solid tumors, volume II [0.03%]
社区系列：细胞网络在儿童及成人实体肿瘤抗肿瘤免疫中的作用（第二卷） 编辑部
Ombretta Melaiu,Elin Bernson,Silvia Pesce
Ombretta Melaiu
Natsuko Saito-Sasaki,Yu Sawada
Natsuko Saito-Sasaki
Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory skin disorder that significantly impairs quality of life. While its pathogenesis involves genetic, immunologic, and environmental components, emerging evidence highlights th...
Relationship between peripheral blood miR-146b-5p levels and lymphocyte subsets in patients with sepsis and its predictive value for prognosis: a single-center study [0.03%]
脓毒症患者外周血miR-146b-5p水平与淋巴细胞亚群分布的相关性及其预后价值：单中心研究
Sha Cheng,Jiaojiao Wang,Pengfei Wang et al.
Sha Cheng et al.
Background: Sepsis is a life-threatening disease with challenges in clinical management due to delayed diagnosis and immunosuppression. Lymphopenia is a key prognostic indicator in sepsis. microRNAs (miRNAs) are recognize...