Gut microbiota and sepsis-associated acute kidney injury: a narrative review [0.03%]
肠道微生物群与脓毒症相关急性肾损伤：综述性文章
Hui Zhang,Bingling Fan,Ruze Ma et al.
Hui Zhang et al.
Background: Sepsis-associated acute kidney injury (SA-AKI) carries high morbidity and mortality, yet its pathogenesis remains incompletely understood. Emerging evidence underscores the gut-kidney axis as a critical pathwa...
The SIRT1/STAT3 axis as a central regulator of immune, inflammatory, and lipid metabolic dysregulation in rheumatoid arthritis: therapeutic implications [0.03%]
SIRT1/STAT3信号轴在类风湿关节炎免疫紊乱、炎症和脂质代谢失调中的作用及其治疗意义
Chengzhi Cong,Yuan Wang,Jian Liu
Chengzhi Cong
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, joint destruction, and systemic comorbidities, particularly cardiovascular disease (CVD) associated with severe dyslipidemia. The bidirectiona...
The role and mechanisms of multiple immunoregulatory cells in pulmonary tuberculosis [0.03%]
多种免疫调节细胞在肺结核发病中的作用及机制研究
Hao Liu,Ping Li,Sujuan He et al.
Hao Liu et al.
Pulmonary tuberculosis (PTB) is a complex respiratory illness and a leading cause of mortality from infectious diseases globally. The regulation of the host immune response is integral to the chronic infection process of PTB. In this proces...
Melanoma stem cells drive macrophage reprogramming to a hybrid phenotype, modulating melanoma stemness and compromising NK cell-mediated immunity [0.03%]
黑色素瘤干细胞驱动巨噬细胞重编程至杂合表型并调节NK介导的免疫反应
Martina Anselmi,Michela Francesconi,Tiziana Triulzi et al.
Martina Anselmi et al.
Introduction: Melanoma stem cells may contribute to tumor progression not only through intrinsic plasticity, but also by shaping the immune microenvironment. However, their interaction with the monocyte-macrophage compart...
Critical changes in whole-brain gene networks in response to small-cell lung cancer as revealed by single-nucleus RNA sequencing [0.03%]
单细胞核RNA测序揭示的小细胞肺癌响应下的全脑基因网络的关键变化
Jingwei Duan,Qi Fu,Yongkun Huo et al.
Jingwei Duan et al.
Background: Small-cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy in which neural activity is implicated in tumor progression. Nevertheless, whether primary SCLC elicits systemic effects on the br...
Swimming ameliorates intervertebral disc degeneration accompanied by Rpl23a downregulation and changes in its immune-inflammatory pathway [0.03%]
游泳改善Rpl23a下调及其免疫炎性通路改变伴随的椎间盘退变
Yong Ji,Haixin Ma,Rong Tan et al.
Yong Ji et al.
Background: Intervertebral disc degeneration (IVDD) is characterized by persistent inflammation and extracellular matrix degradation, but the driving mechanism of immune dysregulation in the intervertebral disc remains un...
Microglia-vascular interactions after spinal cord injury: regulatory mechanisms and therapeutic advances [0.03%]
脊髓损伤后的小胶质细胞-血管相互作用：调控机制和治疗进展
Yulin Zhao,Weiyun Wang,Shihao Li et al.
Yulin Zhao et al.
The repair process following spinal cord injury (SCI) involves intricate crosstalk between neuroimmune and vascular systems, with microglia-vascular interactions increasingly recognized as an important regulatory interface that may shape bo...
Editorial: Community series in towards precision medicine for immune-mediated disorders: advances in using big data and artificial intelligence to understand heterogeneity in inflammatory responses, volume III [0.03%]
组约：通向免疫介导性疾病精确诊疗的社区系列（第三卷）——运用大数据及人工智能理解炎症反应异质性的进展
Xu-Jie Zhou,Le-Ting Zhou,Celine C Berthier et al.
Xu-Jie Zhou et al.
Codonopsis pilosula polysaccharide attenuates the inflammatory response in macrophages induced by Brucella abortus outer membrane protein 19 via regulating ATP2A1 to modulate cell adhesion and calcium signaling [0.03%]
党参多糖通过调节ATP2A1改善外膜蛋白19诱导的巨噬细胞炎症反应及黏附作用
Xuxu Wang,Zhiyong Zhou,Nan Zhang et al.
Xuxu Wang et al.
Brucellosis is a zoonotic disease caused by Brucella species. Its pathogenesis is closely associated with bacterial evasion of macrophage-mediated killing, induction of a pro-inflammatory cytokine storm, and immune-mediated pathological dam...
Prognostic inflammatory-immune score-based risk stratification optimizes adjuvant therapy for non-gastric gastrointestinal stromal tumors: a multicenter study [0.03%]
基于预后炎症免疫评分的危险度分层优化非胃肠道间质瘤患者的辅助治疗：多中心研究
Zhiming Cai,Zhengnan Xu,Huimei Lin et al.
Zhiming Cai et al.
Background: Conventional modified National Institutes of Health (mNIH) and Armed Forces Institute of Pathology (AFIP) systems exhibit "anatomical bias" due to their development from predominantly gastric cohorts, resultin...
Multicenter Study
Frontiers in immunology. 2026 Jun 2:17:1846854. DOI:10.3389/fimmu.2026.1846854 2026