NGS identifies novel HLA-DQA1 and DPB1 associations with aplastic anemia in the Kazakhstani population [0.03%]
利用NGS在哈萨克族人群中的再生障碍性贫血与HLA-DQA1和DPB1的新关联研究
Aida Turganbekova,Zhulduz Zhanzakova,Perizat Kanabekova et al.
Aida Turganbekova et al.
Background: Aplastic anemia (AA) is a rare but serious blood disorder defined by autoimmune-driven destruction of bone marrow stem and progenitor cells. HLA polymorphisms are AA risk factors, with population-specific asso...
Targeting pyroptosis in periodontitis: mechanisms and therapeutic strategies [0.03%]
牙周炎中焦亡的靶向治疗：机制和策略
Yusen Qie,Jiaxin Li,Yang Xu et al.
Yusen Qie et al.
Periodontitis is a common chronic inflammatory disease of the oral cavity. It is characterized by progressive destruction of the periodontal supporting tissues and alveolar bone loss, and it remains a leading cause of tooth loss in adults. ...
Comprehensive analysis of mitochondrial unfolded protein response related genes for prognosis and therapeutic response in pancreatic cancer [0.03%]
胰腺癌中与线粒体未折叠蛋白反应相关基因的预后和治疗反应的全面分析
Chengqing Li,Cuiling Lu,Zheng Ma et al.
Chengqing Li et al.
Background: Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system, with an extremely poor prognosis. The mitochondrial unfolded protein response (UPRmt) can maintain mitochondrial homeostasis an...
First 2-year experience of nationwide newborn screening for severe forms of T and B cell immunodeficiency: 2.3 million newborns analyzed using TREC and KREC in Russia [0.03%]
俄罗斯新生儿T和B细胞免疫缺陷严重形式的全国性筛查首次两年经验：分析230万新生儿使用TRECS和KRECS
Andrey Marakhonov,Anna Mukhina,Irina Efimova et al.
Andrey Marakhonov et al.
Introduction: Here, we present the results of a nationwide newborn screening (NBS) program in Russia, covering over 2.3 million newborns and employing TREC and KREC quantification to improve the identification of severe f...
Xiaoyao San alleviates emotional distress - induced TNBC growth through augmenting intratumoral CD8+T cell infiltration mediated by Rela/NF-kB-Cxcl9 axis [0.03%]
逍遥散通过Rela/NF-κB-Cxcl9轴增强小鼠免疫循环中瘤内CD8+t细胞浸润来缓解情感压力诱导的三阴性乳腺癌生长
Yuqi Liang,Yingchao Wu,Jieting Chen et al.
Yuqi Liang et al.
Background: Emotional distress (ED) is closely associated with the progression of triple-negative breast cancer (TNBC). Xiaoyao San (XYS), a classical Chinese herbal prescription traditionally used for mood regulation, ha...
Possible role of pre-vaccination T-lymphocyte subpopulations in the antibody response to COVID-19 vaccines in children undergoing chemotherapy [0.03%]
化疗儿童中疫苗接种前T淋巴细胞亚群在COVID-19疫苗抗体反应中的潜在作用
Csaba Péterfia,Zsolt I Komlósi,Zoltán Pós et al.
Csaba Péterfia et al.
Background: In a previous study, we found a possible connection between pre-vaccination CD3+CD56+ T cells and seroresponse to influenza vaccination in immunosuppressed patients. Decreased circulating CD3+CD56+ T cells hav...
Multicenter Study
Frontiers in immunology. 2026 Feb 5:17:1728845. DOI:10.3389/fimmu.2026.1728845 2026
The microbial peace-signal hypothesis: distributed immune "peace hubs" across the human body [0.03%]
微生物和平信号假说：遍布人体的分布式免疫“和平中心”理论
Cliff Shunsheng Han
Cliff Shunsheng Han
The human immune system depends on microbial partners to maintain restraint. Short-chain fatty acids (SCFAs), produced by anaerobic fermenters in the gut, mouth, and skin, act as biochemical "peace signals" that calm immune activation and p...
Predictors and responses to varying durations of BTK inhibitor bridging therapy before anti-CD19 CAR-T cell therapy in patients with relapsed/refractory DLBCL [0.03%]
替雷利珠单抗联合吉西他滨和放疗治疗不可切除局部复发性/远处转移鼻咽癌的疗效及安全性探索：一项前瞻性、多中心、单臂、Ⅱ期临床试验
Jia Wang,Rui Cui,Yao Qi et al.
Jia Wang et al.
Background: Anti-CD19 chimeric antigen receptor (CAR)-T cell therapy has demonstrated clinical potential in treating relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL); however, enhancing its therapeutic e...
Clinical Trial
Frontiers in immunology. 2026 Feb 6:17:1674235. DOI:10.3389/fimmu.2026.1674235 2026
Tuft-cell-derived IL-25 regulates intestinal ILC2 in response to Brucella infection [0.03%]
tuft细胞衍生的il-25调节布鲁氏菌感染时的肠驻留ilc2细胞
Kaiyu Shang,Na Chen,Tingting Tian et al.
Kaiyu Shang et al.
Introduction: Brucella is a zoonotic pathogen capable of invading the host through the intestinal mucosa. However, the immune mechanisms underlying intestinal infection remain poorly understood. Tuft cells are specialized...
Correction: Editorial: Recent trends and advancements in multispectral and hyperspectral imaging for cancer detection [0.03%]
更正：编辑部文章：癌症检测中多光谱和高光谱成像的最新趋势和进展
I-Chen Wu,Hsiang-Chen Wang,Arvind Mukundan
I-Chen Wu
[This corrects the article DOI: 10.3389/fimmu.2025.1752197.]. Keywords: cancer detection; deep learning; hyp...
Published Erratum
Frontiers in immunology. 2026 Feb 5:17:1798272. DOI:10.3389/fimmu.2026.1798272 2026