Biportal endoscopic spinal surgery for thoracic ossification of the ligamentum flavum: a study of different classification types and surgical outcomes [0.03%]
双通道内镜下胸腰段黄韧带骨化病变手术治疗的临床研究及疗效评估
Honggang Wang,Dongqing He,Ruxing Liu et al.
Honggang Wang et al.
Background: This study aimed to assess potential differences in the clinical effectiveness of biportal endoscopic spinal surgery (BESS) for treating various axial classifications of ossification of the ligamentum flavum (...
Effects of remote transitional care on stroke patients: a meta-analysis [0.03%]
远程过渡照护对卒中患者影响的meta分析
Lili Bai,Yenan Shen,Huafen Gu
Lili Bai
Background: Stroke is a leading cause of adult disability and mortality worldwide. Although advances in acute stroke care have improved survival rates, challenges remain in the post-discharge transitional period. Remote t...
Impact of cerebral small vessel disease burden and systemic clinical phenotypes on short-term neurological outcomes after acute ischemic stroke [0.03%]
急性缺血性卒中患者脑小血管病负荷和全身临床表型对短期神经功能预后的影响
Lifang Ma,Fangtong Liu,Jing Deng et al.
Lifang Ma et al.
Introduction: Cerebral small vessel disease (CSVD) is increasingly recognized as an important determinant of outcome after acute ischemic stroke (AIS). However, the contribution of global CSVD burden, individual imaging m...
A prognostic model incorporating MCP-1 and IL-8 for early risk stratification in acute ischemic stroke patients receiving intravenous thrombolysis: a retrospective development with temporal validation [0.03%]
一种结合MCP-1和IL-8的评分模型，用于静脉溶栓治疗的急性缺血性卒中患者的早期危险分层：回顾性研究及时间验证
Huiyuan Zhang,Lei Si,Yamin Song et al.
Huiyuan Zhang et al.
Objective: To investigate the expression characteristics of monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) in patients with acute ischemic stroke (AIS) who received intravenous thrombolysis and their ...
Efficacy and safety of acupuncture for post-stroke spasticity: a study protocol for a randomized controlled trial [0.03%]
针刺治疗卒中后肌张力异常有效性和安全性的临床试验方案
Zhihao Xiong,Juwei Dong,Yingying Zhu et al.
Zhihao Xiong et al.
Background: Post-stroke spasticity (PSS) is a common motor complication during stroke recovery, imposing a substantial burden on both individuals and society owing to its high morbidity and disability rates. Current evide...
Predictive value of multimodal neurological monitoring in the postoperative neurological dysfunction after cardiovascular surgery with cardiopulmonary bypass [0.03%]
心血管手术中应用体外循环后多模神经功能监测的预测价值
Miao Zou,Xiang Tan,Xinli Zhang et al.
Miao Zou et al.
Objective: The use of multimodal neurologic monitoring (MNM) has rarely been reported in monitoring patients after cardiovascular surgery with cardiopulmonary bypass. This prospective observational cohort aims to the effe...
Machine learning-based prediction model for cognitive frailty in elderly patients with ischaemic stroke: a prospective cohort study [0.03%]
基于机器学习的预测模型在老年缺血性卒中患者认知衰弱中的应用：前瞻性队列研究
Xuan Chen,Linjie Zhou,Ying Zhang et al.
Xuan Chen et al.
Background: Cognitive frailty (CF), which is characterised by the coexistence of cognitive impairment and physical frailty, is common among older patients after ischaemic stroke (IS) and is associated with adverse functio...
MRI markers of glymphatic dysfunction in tuberculous meningitis: associations with CSF proteins and cognitive impairment [0.03%]
结核性脑膜炎的MRI标志物：与脑脊液蛋白和认知障碍的关系
Yilin Wang,Wei He,Yongbo Li et al.
Yilin Wang et al.
Objectives: Tuberculous meningitis (TBM), a central nervous system infection, is frequently complicated by mild cognitive impairment (MCI). Although imaging markers of glymphatic function have been shown to correlate with...
Neuronal exosomal miR-25-3p attenuates M1 microglial activation and neurotoxicity by targeting TLR4 to regulate the NF-κB signaling pathway [0.03%]
神经元外泌体miR-25-3p通过靶向TLR4调节NF-κB信号通路来缓解M1型小胶质细胞激活和神经毒性
Guangjun Hu,Sarulatuya,Siyu Du et al.
Guangjun Hu et al.
Background: Perioperative neurocognitive disorders (PND) are severe postoperative complications in the elderly, with neuroinflammation driven by pro-inflammatory M1 microglia being a core pathological mechanism. This stud...
Evaluating the efficacy of rimegepant as a preventive treatment for chronic and episodic migraine: a three-month longitudinal retrospective cohort study [0.03%]
评估rimegepant作为慢性 migraine和发作性migraine预防治疗的有效性：一项为期三个月的回顾性队列研究
Hamza Khan,Muhammad Saqib Khan,Sheraz Khan et al.
Hamza Khan et al.
Background: Rimegepant, an oral calcitonin gene-related peptide receptor antagonist approved for both acute and preventive migraine treatment, demonstrates efficacy in clinical trials, but real-world evidence remains limi...