Eupalinolide A inhibits cancer progression and induces ferroptosis and apoptosis by targeting the AMPK/mTOR/SCD1 signalling in non-small cell lung cancer [0.03%]
埃帕林醇A通过靶向AMPK/mTOR/SCD1信号通路抑制非小细胞肺癌的发展并诱导铁死亡和凋亡
Yonghui Zhang,Chen Wang,Xiyang Zhang et al.
Yonghui Zhang et al.
Background: Non-small cell lung cancer (NSCLC) is a common malignancy with limited efficacy of established therapies and a poor prognosis that often entails a high financial burden. Eupatorium lindleyanum DC. and its main...
The role of sea buckthorn in skin and mucosal health: a review from an anti-inflammatory perspective [0.03%]
海浆果在皮肤和黏膜健康中的作用：一种抗炎视角的综述
Xiayinan Song,Xinyao Sun,Huimin Yuan et al.
Xiayinan Song et al.
The skin and mucosal barriers serve as essential frontline defenses, protecting against pathogens, environmental insults, and excessive water loss while maintaining physiological homeostasis. Sea buckthorn (Hippophae rhamnoides), a plant lo...
Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series [0.03%]
儿童误食大麻后过量中毒的临床表现和毒性动力学——病例系列研究报告
Alessia Cafaro,Federica Pigliasco,Sebastiano Barco et al.
Alessia Cafaro et al.
Accidental exposure to edible cannabis products in children is an increasing public health concern. The clinical presentation is often nonspecific, which can delay diagnosis and lead to inappropriate management. Toxicological screening is t...
A comparative analysis of biologics market dynamics in 12 countries: (Bio)similar and sustainability [0.03%]
十二个国家生物制剂市场的比较分析：相似性与可持续发展
Younghyun Song,Gyeongseon Shin,Gyeyoung Choi et al.
Younghyun Song et al.
Objective: We sought to evaluate the relationship between biosimilar introduction and the prices and expenditures of biologics in high-income countries. M...
A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for etrasimod [0.03%]
一项基于美国食品药品管理局不良事件报告系统（FAERS）的Etrasimod真实世界药物警戒研究
Yingxiu Wu,Wei Ke,Huibiao Li
Yingxiu Wu
Objective: To characterize the post-marketing safety profile of etrasimod using the latest data from the FDA Adverse Event Reporting System (FAERS), and to provide a comparative analysis versus other sphingosine-1-phospha...
Optimization of response surface methodology for the extraction of isoliquiritigenin from Aspergillus niger solid-state fermentation of licorice and its antitumor effects [0.03%]
相应面法优化甘草来源植物乳杆菌黑色素状态发酵液隔离黄酮及其抗肿瘤作用
Jingwei Hao,Qiuxuan Li,Nan Dong et al.
Jingwei Hao et al.
This research focused on optimizing the extraction of isoliquiritigenin (ISL) from licorice via a solid-state fermentation process involving Aspergillus niger. Isoliquiritigenin was quantified through high-performance liquid chromatography ...
Correction: Editorial: Opportunities and challenges in drug repurposing [0.03%]
社论：药物再利用的机会与挑战——勘误启事
Ihosvany Camps,Stephan R Künzel,Mario Schubert et al.
Ihosvany Camps et al.
[This corrects the article DOI: 10.3389/fphar.2025.1709217.]. Keywords: artificial intelligence; bioinformat...
Published Erratum
Frontiers in pharmacology. 2025 Nov 11:16:1735051. DOI:10.3389/fphar.2025.1735051 2025
Differential effects of Huang-Lian-Jie-Du Decoction on Alzheimer's disease and normal rats [0.03%]
黄连解毒汤对阿尔茨海默病模型小鼠和正常小鼠的差异性作用研究
Manru Xu,Yue Zhu,Jinxin Chen et al.
Manru Xu et al.
Introduction: Huang-Lian-Jie-Du Decoction (HLJDD), a botanical drug used in traditional medicine, has been used in the management of Alzheimer's disease (AD). However, the mechanisms underlying its preventive effects rema...
HPV vaccine-related thyroid adverse events: temporal patterns and reporting trends [0.03%]
人乳头瘤病毒疫苗相关甲状腺不良事件：时间模式和报告趋势
Liying Song,Jingkai Di,Jiaolin Fan et al.
Liying Song et al.
Background: Human papillomavirus (HPV) vaccination is essential for cervical cancer prevention, but concerns about thyroid-related adverse events (AEs) have emerged. ...
Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies [0.03%]
黄芪多糖联合放射及化学疗法治疗子宫颈癌：随机对照试验的系统综述和荟萃分析
Tao Sun,Ruping Zhao,Yaling Zhang et al.
Tao Sun et al.
Backgrounds: Cervical cancer ranks among the most common malignant tumors affecting women globally. Currently, radiotherapy and chemotherapy are commonly used treatments for cervical cancer, yet they are often accompanied...