Editorial: Model organisms in neuroinflammation and neuropathy: Drosophila melanogaster [0.03%]
编者按：神经炎症和神经病的模型生物——果蝇(Drosophila melanogaster)
Zihan Huang,Xueji Dai,Baichun Jiang et al.
Zihan Huang et al.
Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease [0.03%]
弥散张量成像及功能磁共振成像显示成人起病神经细胞内包涵体疾病的微结构及网络连接异常
Rui Zhu,Junyu Qu,Yongsheng Wu et al.
Rui Zhu et al.
Objectives: Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disorder lacking reliable neuroimaging biomarkers. This study aimed to evaluate microstructural and functional connectivity alteration...
Genetically stratified Parkinson's disease with freezing of gait is related to specific pattern of cognitive impairment and non-motor dominant endophenotype [0.03%]
遗传分型的帕金森病冻结步态与特定的认知障碍和非运动优势表型相关
Lukas Pavelka,Rajesh Rawal,Stefano Sapienza et al.
Lukas Pavelka et al.
Background: Freezing of gait (FOG) is an important milestone in the individual disease trajectory of people with Parkinson's disease (PD). Based on the cognitive model of FOG etiology, the mechanism behind FOG implies hig...
Association of frailty and serum neurofilament light chain levels: the mediating role of estimated glomerular filtration rate [0.03%]
脆弱性与血清神经丝轻链水平的相关性：肾小球滤过率估计值的中介作用
Wei Yang,Shan Huang,Huanshun Xiao et al.
Wei Yang et al.
Background: Both frailty and elevated serum neurofilament light chain (sNfL) levels are linked to cognitive impairment. However, evidence of their relationship is lacking, and whether it was mediated by renal function was...
Machine learning models for diagnosing Alzheimer's disease using brain cortical complexity [0.03%]
基于大脑皮层复杂度的机器学习模型在阿尔茨海默病诊断中的应用研究
Shaofan Jiang,Siyu Yang,Kaiji Deng et al.
Shaofan Jiang et al.
Objective: This study aimed to develop and validate machine learning models (MLMs) to diagnose Alzheimer's disease (AD) using cortical complexity indicated by fractal dimension (FD). ...
Identification of key proteins in early-onset Alzheimer's disease based on WGCNA [0.03%]
基于WGCNA的早发型阿尔茨海默病关键蛋白识别
Dazhi Li,Yaxin Wang,Jinliang Wang et al.
Dazhi Li et al.
Introduction: Early-onset Alzheimer's disease (EOAD) is sporadic, highly heterogeneous, and its underlying pathogenic mechanisms remain largely elusive. Proteomics research aims to uncover the biological processes and key...
Grip strength and depressive symptoms in Chinese middle-aged and older adults: the mediating effects of cognitive function [0.03%]
中国中老年人握力与抑郁症状的关系：认知功能的中介作用
Xinzheng Wang,Lifei Wu,Huifen Zhou et al.
Xinzheng Wang et al.
Objective: This study investigates the associations and mediating pathways between grip strength, cognitive function, and depression in middle-aged and elderly individuals in China. ...
Emerging role of microglia in inter-cellular transmission of α-synuclein in Parkinson's disease [0.03%]
小胶质细胞在帕金森病细胞间α-突触核蛋白传播中的作用不容忽视
Xiangbo Zhang,Haiyang Yu,Juan Feng
Xiangbo Zhang
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide, significantly prejudicing the health and quality of life of elderly patients. The main pathological characteristics of PD are the loss of dopaminergic n...
Sources of perceived social support and cognitive function among older adults: a longitudinal study in rural China [0.03%]
中国农村老年人认知功能与感知社会支持来源：一项纵向研究
Shiqi Gui,Jing Wang,Qiushuo Li et al.
Shiqi Gui et al.
Background: Studies have shown the positive impact of perceived social support on cognitive function among older adults in rural areas. However, existing studies often overlook the impact of different support sources. Thi...
Neural effects of multisensory dance training in Parkinson's disease: evidence from a longitudinal neuroimaging single case study [0.03%]
帕金森病的多感官舞蹈训练的神经效应：来自纵向神经影像单病例研究的证据
Jenny R Simon,Judith Bek,Katayoun Ghanai et al.
Jenny R Simon et al.
Dance is associated with beneficial outcomes in motor and non-motor domains in Parkinson's disease (PD) and regular participation may help delay symptom progression in mild PD. However, little is known about the neurobiological mechanisms o...