Age-dependent phenotypes of cognitive impairment as sequelae of SARS-CoV-2 infection [0.03%]
SARS-CoV-2感染后各年龄段的认知障碍特征表型不同
Gabriela Gonzalez Aleman,George D Vavougios,Carmela Tartaglia et al.
Gabriela Gonzalez Aleman et al.
Cognitive changes associated with PASC may not be uniform across populations. We conducted individual-level pooled analyses and meta-analyses of cognitive assessments from eight prospective cohorts, comprising 2,105 patients and 1,432 contr...
Inclusion of hypocretin-1 improved performance of poor sleep quality prediction for elderly patients with acute ischemic stroke: a prospective cohort study [0.03%]
纳入下丘脑分泌素-1可改善急性缺血性卒中伴睡眠质量差老人的预测性能:前瞻性队列研究
Ting Fu,Weiwei Zhang,Rongrong Guo et al.
Ting Fu et al.
Background: Hypocretin-1 is a vital neurotransmitter in regulating the sleep-wake cycle and provides neuroprotection against cerebral ischemia. We aims to develop a poor sleep quality predictive model for elderly populati...
Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer's disease, and Parkinson's disease: a Mendelian randomization study [0.03%]
代谢特征在失眠、阿尔茨海默病和帕金森病共病中的作用:一项孟德尔随机化研究
Chengyong Liu,Chi Wang,Jing Jiang et al.
Chengyong Liu et al.
Objective: There reportedly exists a significant comorbidity between insomnia and neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), indicative of a potential link to serum metaboli...
An EEG-based framework for automated discrimination of conversion to Alzheimer's disease in patients with amnestic mild cognitive impairment: an 18-month longitudinal study [0.03%]
基于EEG的鉴别轻度认知障碍患者转化为阿尔茨海默病的自动化框架:一项18个月纵向研究
Yingfeng Ge,Jianan Yin,Caie Chen et al.
Yingfeng Ge et al.
Background: As a clinical precursor to Alzheimer's disease (AD), amnestic mild cognitive impairment (aMCI) bears a considerably heightened risk of transitioning to AD compared to cognitively normal elders. Early predictio...
Editorial: Animal models of Alzheimer's disease and other dementias: past, present, and future [0.03%]
论著:阿尔茨海默病及其他痴呆动物模型的过去、现在和未来
Ines Moreno-Gonzalez,Jesus Garcia-Martin,Roberta Marongiu
Ines Moreno-Gonzalez
Sleep structure of short-term insomnia disorder with mild cognitive impairment in older adults and their correlation with cognitive function: a case-control study [0.03%]
轻度认知障碍老年人短期失眠障碍患者的睡眠结构及其与认知功能的关系:病例对照研究
Jinkun Zeng,Jia Wei,Ruobing Qi
Jinkun Zeng
Objectives: This study seeks to delineate the sleep architecture characteristics in older adults with short-term insomnia and mild cognitive impairment (MCI) and to explore their association with cognitive performance. ...
Pharmacological enhancement of slow-wave activity at an early disease stage improves cognition and reduces amyloid pathology in a mouse model of Alzheimer's disease [0.03%]
药理学增强阿尔茨海默病小鼠模型早期疾病阶段的慢波活动可改善认知并减少淀粉样蛋白病理损伤
Sedef Kollarik,Dorita Bimbiryte,Aakriti Sethi et al.
Sedef Kollarik et al.
Introduction: Improving sleep in murine Alzheimer's disease (AD) is associated with reduced brain amyloidosis. However, the window of opportunity for successful sleep-targeted interventions, regarding the reduction in pat...
Research on the application of functional near-infrared spectroscopy in differentiating subjective cognitive decline and mild cognitive impairment [0.03%]
近红外光谱技术在主观认知下降和轻度认知障碍鉴别中应用的研究
Zheng Wang,Chaojie Niu,Yong Duan et al.
Zheng Wang et al.
Introduction: Alzheimer's disease (AD) is a common neurological disorder. Based on clinical characteristics, it can be categorized into normal cognition (NC), subjective cognitive decline (SCD), mild cognitive impairment ...
Effects of different exercise types on balance function in healthy older adults and Parkinson's patients: a systematic review [0.03%]
不同类型运动对健康老年人和帕金森病患者平衡功能影响的系统综述
Xu Bin Guo,Lu Tang
Xu Bin Guo
Objective: This study aims to compare the effects of Tai Chi, yoga, and resistance training on balance function in healthy elderly individuals and patients with Parkinson's disease (PD). Given the well-documented benefits...
Environmental enrichment is associated with favorable memory-related functional brain activity patterns in older adults [0.03%]
环境富集与老年人有利的记忆相关脑功能活动模式有关
Simon Hass,Maxie Liebscher,Anni Richter et al.
Simon Hass et al.
Background: In humans, environmental enrichment (EE), as measured by the engagement in a variety of leisure activities, has been associated with larger hippocampal structure and better memory function. The present cross-s...