Combining plasma biomarkers, clinical parameters, and neuroimaging features for differential diagnosis of Parkinson's disease and atypical parkinsonian syndromes: a multidimensional modeling approach [0.03%]
结合血浆生物标志物、临床参数和神经影像特征对帕金森病和非典型帕金森综合征进行鉴别诊断：一种多维度建模方法
Jian Yao,Jiajia Ma,Peng Li et al.
Jian Yao et al.
Background: The early differential diagnosis of Parkinson's disease (PD) and atypical parkinsonian syndromes (APSs) poses challenges. The current methods, which rely on clinical assessments and single-modal biomarkers, la...
Effect of deep brain stimulation on dysphagia in Parkinson's disease: mechanisms, evidence, and outlook [0.03%]
帕金森病深部脑刺激与吞咽障碍：机制、证据和展望
Jule Hofacker,Bahne H Bahners,Cinja Huber et al.
Jule Hofacker et al.
Introduction: Oropharyngeal dysphagia (OD) is a common and significant complication of Parkinson's disease (PD), contributing to malnutrition, respiratory complications and impaired medication intake. The pathophysiology ...
Early and progressive retinal microglial changes in APPNL-F/NL-F mouse model of Alzheimer's disease revealed by an automated image analysis software [0.03%]
APPNL-F/NL-F阿尔茨海默病小鼠模型中早期视网膜小胶质细胞变化的自动化图像分析软件发现报告
Lidia Sánchez-Puebla,Inés López-Cuenca,Miguel A Sánchez-Puebla et al.
Lidia Sánchez-Puebla et al.
Alzheimer's disease (AD) is characterized by the accumulation of misfolded proteins that trigger neuroinflammation and neuronal loss. The retina, as an extension of the central nervous system, mirrors these pathological processes and repres...
The validity of visual and hearing impairment in predicting dementia and cognitive impairment in older adults: a systematic review and meta-analysis [0.03%]
老年人视觉和听力损伤预测痴呆症和认知障碍的可靠性的系统评价和meta分析
Qingwen Gan,Yiling Yuan,Qianqian Hu et al.
Qingwen Gan et al.
Objective: The number of people with dementia and cognitive impairment is rising every year as the older population grows. The higher prevalence and mortality rates of dementia and cognitive impairment place an enormous b...
After cochlear implantation in older adults, enhanced working memory does not fully mediate the relationship between CI and improved semantic fluency [0.03%]
人工耳蜗植入老年人后的优势工作记忆不能完全介导人工耳蜗与改善语义流畅度之间的关系
Maria Huber,Angelika Illg,Lisa Reuter et al.
Maria Huber et al.
Aim: Studies indicate that semantic fluency improved after cochlear implantation (CI) in older adults, but not in young and middle-aged adults. We were interested in identifying cognitive variables that are associated wit...
Research progress on 40 Hz sensory stimulation for the treatment of Alzheimer's disease [0.03%]
40赫兹感觉刺激治疗阿尔茨海默病的研究进展
Bing Tang,Ming Tao
Bing Tang
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by β-amyloid (Aβ) deposition, tau protein hyperphosphorylation, and synaptic dysfunction. In recent years, 40 Hz sensory stimulation-including visual, audito...
Polarity-dependent modulation of sleep oscillations and cortical excitability in aging [0.03%]
极性依赖的睡眠振荡和老年皮层兴奋性的调节
Buse Dikici,Robert Malinowski,Jan-Bernhard Kordaß et al.
Buse Dikici et al.
Background: During non-rapid eye movement (NREM) sleep, cortical slow oscillation (SO;
A cross-database bibliometric analysis of rapid eye movement sleep behavior disorder in Parkinson's disease research [0.03%]
帕金森病REM睡眠行为障碍的文献计量分析
Shengjie Du,Xijiang Tian,Rui Ren et al.
Shengjie Du et al.
Background: Rapid eye movement sleep behavior disorder (RBD) is increasingly recognized as both a prodromal marker and a significant predictor of Parkinson's disease (PD) progression. Despite a surge in related research, ...
Electroacupuncture alleviates Parkinson's disease by targeting HDAC/SIRT-mediated deacetylation of 14-3-3 [0.03%]
电针通过靶向HDAC/SIRT介导的14-3-3去乙酰化治疗帕金森病
Zhao-Qin Wang,Han-Dan Zheng,Ling-Jie Li et al.
Zhao-Qin Wang et al.
Introduction: Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons and the accumulation of pathological α-synuclein. Although current treatments can alleviate symptom...
Cardiorespiratory fitness does not predict longitudinal changes in manual dexterity, cognition or corticospinal excitability in multiple sclerosis [0.03%]
心肺功能无法预测多发性硬化患者手动操作能力、认知或皮质脊髓兴奋性的纵向变化
Basel Mohamed,Sarah Duraid,Nick W Bray et al.
Basel Mohamed et al.
Introduction: Neurodegeneration in multiple sclerosis leads to progressive cognitive and motor impairments. Cardiorespiratory fitness (CRF) is thought to protect against such decline, but its longitudinal effects remain u...