Hippocampal formation-cortical high-fidelity memory networks in healthy older adults during the mnemonic discrimination task [0.03%]
健康老年人在情节记忆任务过程中的海马-皮层高保真记忆网络
Joseph C C Chen,Adam Gazzaley,Peter E Wais
Joseph C C Chen
Introduction: Fidelity of detailed information retrieved from long-term memory (LTM) declines in aging due to changes affecting learning and remembering processes. Such behavioral deficits correspond with functional alter...
Neuromuscular characteristics of dynamic balance control in patients with sarcopenia: a combined analysis of surface electromyography and limits of stability [0.03%]
肌少症患者动态平衡控制的神经肌肉特征:表面肌电图和稳定极限的联合分析
Jingchun Wang,Ting Zhang,Qian Qian et al.
Jingchun Wang et al.
Introduction: Sarcopenia is a major risk factor for falls in older adults; however, the neuromuscular characteristics underlying dynamic balance deficits remain poorly understood. ...
Comparative efficacy and certainty of evidence of exercise interventions for cognitive outcomes in older adults with mild cognitive impairment: a systematic review and network meta-analysis of randomized controlled trials [0.03%]
运动干预改善轻度认知障碍老年人认知功能的比较疗效和证据确定性:随机对照试验的系统综述和网络meta分析
Bu-Yu Liu,Chang-Kuan Zhuang,Hui Ruan
Bu-Yu Liu
Background: Mild cognitive impairment (MCI) is common in older adults and is linked to dementia, functional decline, and poorer quality of life. Exercise is recommended as a non-pharmacological strategy, but comparative e...
Integrated PET/MRI for the evaluation of gray matter atrophy and metabolic changes in idiopathic Parkinson's disease [0.03%]
帕金森病患者皮质萎缩和代谢变化的整合正电子发射型计算机断层扫描/核磁共振成像评估
Yanxia Yu,Yujie Bai,Shasha Xu et al.
Yanxia Yu et al.
Background: The underlying mechanisms linking structural and metabolic alterations of idiopathic Parkinson's disease (IPD) remain poorly understood. Utilizing integrated PET/MR for its precise spatial correlation, this st...
The association between body composition and orthostatic hypotension in patients with neurodegenerative disorders in parkinsonism-related multidisciplinary clinic [0.03%]
帕金森病相关多学科门诊的神经退行性疾病患者体成分与直立性低血压的相关性
Jin Fu,Rui Wang,Wengkei Wong et al.
Jin Fu et al.
Introduction: Orthostatic hypotension (OH) commonly impairs the quality of life and prognosis of patients with neurodegenerative disorders. Since skeletal muscle functions as a peripheral pump for blood pressure stabiliza...
Chronic stress, cortisol dysregulation, and neurodegenerative vulnerability: mechanistic pathways linking HPA-axis dysfunction to Alzheimer's disease risk [0.03%]
慢性压力、皮质醇失调与神经退行性易感性:HPA轴功能障碍与阿尔茨海默病风险的机制联系
Danah F Almalki,Rawiyah A Alkabkabi,Raghad A Wayyani et al.
Danah F Almalki et al.
Chronic psychological stress is increasingly recognized as a silent risk factor of long-term brain vulnerability and a potential modifier of neurodegenerative disease trajectories. The persistent activation of the hypothalamic-pituitary-adr...
Glymphatic dysfunction in Alzheimer's disease: a systematic review and meta-analysis of the DTI-ALPS index as an imaging biomarker [0.03%]
阿尔茨海默病甘淋巴系统功能障碍的系统评价和DTI-ALPS指数的meta分析
Yutong Wu,Chen Zhang,Jiayi Yan et al.
Yutong Wu et al.
Introduction: Although the diffusion tensor image analysis along the perivascular space (DTI-ALPS) index is widely utilized as a proxy for glymphatic function in Alzheimer's Disease (AD) research, its association with cor...
A multi-view graph neural network framework for Parkinson's disease identification based on dynamic functional connectivity [0.03%]
基于动态功能连接的帕金森病识别的多视角图神经网络框架
Meili Lu,Xiangyu Zhao,Xile Wei
Meili Lu
Parkinson's disease (PD) is a common neurodegenerative disorder, and accurate diagnosis is crucial for timely intervention. Dynamic functional connectivity (DFC) analysis of resting-state functional magnetic resonance imaging (rs-fMRI) can ...
Imaging the neurohiv brain in animal models: past, present, and future-toward longitudinal, whole-brain aging phenotypes [0.03%]
动物模型中的神经HIV脑影像:过去、现在与未来——纵向的全脑衰老表型研究方向
Paddy Ssentongo,Anna Ssentongo
Paddy Ssentongo
Animal models are essential for defining mechanisms of HIV-associated brain injury in the antiretroviral therapy era, where neurocognitive impairment and brain aging have replaced opportunistic infections as dominant clinical concerns. Huma...
Transcranial direct current stimulation to improve cognitive function in patients with vascular cognitive impairment: a literature review [0.03%]
经颅直流电刺激改善血管性认知障碍患者认知功能的效果观察:文献综述
Jiamian Shi,Xiaodong Li,Ling Guan et al.
Jiamian Shi et al.
Vascular pathology represents the second most common cause of cognitive impairment after Alzheimer's disease and contributes substantially to mixed dementia involving both vascular and neurodegenerative mechanisms. Vascular cognitive impair...