From knowledge landscapes to network mechanisms: charting regulated cell death pathways in ALS [0.03%]
从知识地图到网络机制：ALS细胞死亡通路的研究
Jingxuan Zhang,Zilin Zhao,Tianyue Xiang et al.
Jingxuan Zhang et al.
Objective: To map the research landscape linking amyotrophic lateral sclerosis (ALS) with regulated cell death (RCD) and to integrate bibliometric trends with bioinformatics evidence to identify convergent mechanisms and ...
The effect of hearing ability on dual-task performance following multi-domain training in older adults with mild cognitive impairment: findings from the SYNERGIC trial [0.03%]
老年轻度认知障碍患者多领域训练后听力对双任务表现的影响：SYNERGIC试验结果
Rachel I Downey,Berkley J Petersen,Niroshica Mohanathas et al.
Rachel I Downey et al.
Background: Hearing loss is one of the largest potentially modifiable risk factors for dementia and is linked with poor cognitive-motor dual-task performance (e.g., walking while performing a cognitive task). Hearing loss...
Trends and cross-country inequalities in the global burden of Alzheimer's disease and other dementias among adults aged 65+ years, 1990-2021: a population based study with projections into 2050 [0.03%]
1990年至2021年全球阿尔茨海默病及其他痴呆症的疾病负担及其国家间差异：基于人口数据的研究及至2050年的预测
Sibo Liu,Guozhi Wu,Xiao Ma et al.
Sibo Liu et al.
Background: Alzheimer's disease and other dementias (ADOD) pose a significant global health challenge, with projected annual increases. The growing elderly population exacerbates burdens, underscoring the need for interve...
Gut-kidney-brain axis and daytime sleepiness in Parkinson's disease and chronic kidney disease: an expert narrative review [0.03%]
肠道-肾脏-大脑轴与帕金森病和慢性肾病患者的日间嗜睡：专家叙述性综述
Shanshan Yang,Canmin Zhu,Shihong Xiong et al.
Shanshan Yang et al.
Background: Excessive daytime sleepiness (EDS) is a debilitating comorbidity in over 80% of patients with Parkinson's disease (PD) and chronic kidney disease (CKD). Evidence implicates dysregulation of the gut-kidney-brai...
Retraction: PKCε activation restores loss of PKCε, manganese superoxide dismutase, vascular endothelial growth factor, and microvessels in aged and Alzheimer's disease hippocampus [0.03%]
撤稿：PKCε激活可修复PKCε、锰超氧化物歧化酶、血管内皮生长因子和微血管在老龄和阿尔茨海默病海马体中的损失
Frontiers Editorial Office
Frontiers Editorial Office
[This retracts the article DOI: 10.3389/fnagi.2022.836634.]. Copyright © 2026 Frontiers Editorial Office.
Physical exercise mitigates motor and muscular deficits in the 3xTg-AD model of Alzheimer's disease [0.03%]
身体锻炼可缓解阿尔茨海默病3xTg-AD模型的小鼠运动和肌肉缺陷
Jesús Andrade-Guerrero,Karen León-Arcia,Omar Emiliano Aparicio-Trejo et al.
Jesús Andrade-Guerrero et al.
Introduction: Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide, characterized by progressive cognitive decline and, in advanced stages, marked motor impairments. These motor deficits are ass...
Feasibility randomized controlled trial of a home-based support program for family caregivers of people with Alzheimer's disease [0.03%]
阿尔茨海默病患者的家庭护理人员居家支持项目的可行性随机对照试验
Hongli Liu,Yuanli Jiang,Jiajia Chen et al.
Hongli Liu et al.
Objective: This study aimed to develop and preliminarily evaluate the feasibility of a home-based care program for family caregivers of individuals with Alzheimer's disease (AD). ...
An integrated CSF-serum biomarker model for predicting clinical progression in Alzheimer's disease [0.03%]
整合脑脊液-血浆生物标志物模型预测阿尔茨海默病的临床进展
Xichun Wang,Ye Tang,Qiwen Zhang et al.
Xichun Wang et al.
Background: The early and accurate identification of Alzheimer's disease (AD) remains a significant clinical challenge. Integrating novel peripheral blood-based biomarkers with established cerebrospinal fluid (CSF) measur...
Dual roles of lactate and lactylation modification in the nervous system: neuroprotection and neuroinjury [0.03%]
乳酸和乳酸化修饰在神经系统中的双重作用：神经保护与神经损伤
TianLu Ran,YunLong Shen,DeJian Peng et al.
TianLu Ran et al.
Lactate is the terminal product of anaerobic oxidation within the glucose metabolism pathway. Traditionally, lactate has been regarded as a metabolically insignificant byproduct derived from incomplete oxidation. However, recent evidence su...
Leveraging object detection for early diagnosis of neurodegenerative diseases through radiomic analysis [0.03%]
基于影像组学分析的物体检测在神经退行性疾病早期诊断中的应用
Wenhong Zhi,Zhiguang Liu,Linjian Huang et al.
Wenhong Zhi et al.
Introduction: Early diagnosis of neurodegenerative diseases remains a formidable challenge in modern neuroimaging, due to subtle and heterogeneous brain deterioration patterns in early disease stages. Integrating artifici...