A comprehensive evaluation of the associations between 12 composite inflammatory indices and all-cause mortality after stroke: a multicohort study [0.03%]
缺血性或出血性卒中后全身炎症与全因死亡率关联的多队列研究：基于12种炎症指数的综合评估
Longyi Zheng,Rundong He,Shuang Tang et al.
Longyi Zheng et al.
Background: Inflammation plays a critical role in post-stroke mortality. However, identification of robust and generalizable inflammatory biomarkers for post-stroke mortality remains a challenge. We conducted a comprehens...
Separating cognitive and motor contributions to iADL difficulties in Parkinson's disease [0.03%]
帕金森病患者认知和运动对日常活动障碍的独立贡献分析
Rekha Ravikumar,Marta Statucka,Melanie Cohn
Rekha Ravikumar
Background: Mild Cognitive Impairment (MCI) and dementia are distinguished by whether cognitive deficits interfere with independent performance of instrumental activities of daily living (iADLs). In Parkinson's disease (P...
Development and validation of a prognostic nomogram for predicting ventilator-associated pneumonia risk in elderly large vessel occlusion ischemic stroke after endovascular therapy patients [0.03%]
老年大血管闭塞缺血性卒中患者接受血管内治疗后呼吸机相关性肺炎风险预测预后的列线图构建及验证
Wenfei Liang,Jingling Zhu,Xiuling Yang et al.
Wenfei Liang et al.
Background: Acute ischemic stroke with large vessel occlusion (AIS-LVO) poses a grave threat to the health of the elderly, exhibiting a high degree of disability and mortality. Post-stroke ventilator-associated pneumonia ...
Mechanistic insights into the anti-neuroinflammatory effects of cassia obtusifolia in Parkinson's disease: a network pharmacology-based study [0.03%]
基于网络药理学的番泻叶抗神经炎症效应治疗帕金森病的作用机制研究
Xinfu Lian,Yongjun Bai,Rong Xie et al.
Xinfu Lian et al.
Background: Parkinson's disease (PD) is a chronic neurodegenerative disorder that is closely associated with neuroinflammation, yet effective anti-inflammatory therapies remain limited. This study aimed to elucidate the p...
LRP1 at the crossroads of Aβ clearance and therapeutic targeting in Alzheimer's disease [0.03%]
LRP1在阿尔茨海默病中的Aβ清除和治疗靶点的交汇点
Yuepeng Deng,Haolin Yin,Zihao Lu et al.
Yuepeng Deng et al.
Alzheimer's disease (AD), characterized by progressive cognitive decline, memory impairment and behavioral disturbances, is the most common form of dementia, and no disease-modifying treatments are available to halt or slow its progression....
Altered brain network dynamics and functional connectivity in subjective cognitive decline: an edge-centric network study [0.03%]
主观认知下降患者的脑网络动态和功能连接改变：基于边的网络研究
Xiaofan Wei,Baiwan Zhou,Juanling Li et al.
Xiaofan Wei et al.
Purpose: To explore neurodynamic bases underlying subjective cognitive decline (SCD) based on edge-centric functional network. Methods: ...
The alterations in brain network functional gradients and dynamic functional connectivity in Alzheimer's disease: a resting-state fMRI study [0.03%]
阿尔茨海默病中脑网络功能梯度和动态功能连接的改变：一项静息态fMRI研究
Benqin Liu,Chunbing Chen,Pan Cai et al.
Benqin Liu et al.
Background and purpose: Alzheimer's disease (AD), the most common form of dementia worldwide, is characterized by progressive cognitive decline. Extensive evidence from dynamic functional connectivity (dFC) studies has de...
Follicle-stimulating hormone linked to cognitive decline and amyloid burden in postmenopausal women [0.03%]
促卵泡激素与绝经后妇女的认知衰退和淀粉样蛋白负担有关
Sheng-Min Wang,Chaiho Jeong,Yoo Hyun Um et al.
Sheng-Min Wang et al.
Introduction: Women have a higher risk of developing Alzheimer's disease (AD) than men, with hormonal changes during menopause being a potential factor. However, the exact relationship between these hormonal changes, cogn...
AI agents in Alzheimer's disease management: challenges and future directions [0.03%]
人工智能在阿尔茨海默病管理中的挑战及未来方向
Gerasimos Grammenos,Aristidis G Vrahatis,Konstantinos Lazaros et al.
Gerasimos Grammenos et al.
Neurodegenerative diseases such as Alzheimer's and Parkinson's disease pose a major global healthcare challenge, with cases projected to rise sharply as populations age and effective treatments remain limited. AI has shown promise in suppor...
Functional data analysis of heart rate variability from continuous ECG monitoring in older adults with and without mild cognitive impairment [0.03%]
功能数据分析连续心电图监测老年人心率变异性（有和无轻度认知障碍）
Jiyue Qin,Carol A Derby,Grace Liu et al.
Jiyue Qin et al.
Background: Reduced heart rate variability (HRV) has been associated with cognitive decline in older adults. However, prior research relied on brief in-clinic electrocardiography (ECG) recordings to measure HRV. Using 7-d...