Engagement with the national electronic health records by people with Parkinson's disease [0.03%]
帕金森病患者使用国民电子健康记录的情况
Marijus Giraitis,Isabel Schwaninger,Ivana Paccoud et al.
Marijus Giraitis et al.
Background: People with Parkinson's disease (PwPD) require coordinated, multidisciplinary care, which can be facilitated by Electronic Health Records (EHRs) enabling efficient information exchange and personalized decisio...
High-saturated-fat diet drives female-biased neurodegeneration in Drosophila via oxidative stress and impaired autophagic flux [0.03%]
高饱和脂肪饮食通过氧化应激和自噬流抑制驱动果蝇神经退行性病变的性别二态性
A M Taylor,K L Matzeller,E M McNeill
A M Taylor
Objective: Dietary saturated fat intake has been increasingly linked to dementia risk, yet the mechanisms through which high-fat diets (HFDs) compromise neuronal integrity remain poorly defined. The model organism Drosoph...
Cognitive correlates of decision-making in Parkinson's disease: a systematic review [0.03%]
帕金森病决策过程的认知神经机制：系统综述
Johanna Büchel,Marc Montgomery Lässer,Noelia Peña Arauzo et al.
Johanna Büchel et al.
Introduction: Changes in decision-making (DM) are frequently observed in patients with Parkinson's disease (PD). Despite extensive research, the relationships between DM and various cognitive functions remain incompletely...
Protective effect of baicalein from Pinellia ternate on Alzheimer's disease cell injury: a network pharmacology, molecular docking, and molecular dynamics study [0.03%]
网络药理学、分子对接及分子动力学揭示半夏 Baicalin 对阿尔茨海默病细胞损伤的保护作用研究
Tuo Ji,Lin Wang,Xu Weng et al.
Tuo Ji et al.
Introduction: Alzheimer's disease (AD) constitutes the primary leading cause of dementia. Pinellia ternata (Thunb.) Breit. is a traditional Chinese herb with unclarified potential therapeutic effects against AD. This stud...
Short-term neurovascular and electrophysiological responses to combined visual and vibration stimulation in older adults with mild cognitive impairment [0.03%]
轻度认知障碍老年人联合视觉和振动刺激的短期神经血管和电生理反应
Runhong Yao,Kouji Yamada,Takashi Kuremoto et al.
Runhong Yao et al.
Mild cognitive impairment (MCI) is associated with age-related alterations in neural oscillatory activity and cerebral hemodynamics, while mobility limitations often restrict participation in conventional exercise-based interventions. This ...
Clinical and neuroimaging correlates of motoric cognitive risk syndrome in cerebral small vessel disease: a cross-sectional study [0.03%]
脑小血管病中运动认知风险综合征的临床及影像学特征：横断面研究
Huixin Zhang,Tong Guo,Ran Zhang et al.
Huixin Zhang et al.
Introduction: Cerebral small vessel disease (CSVD) and motoric cognitive risk syndrome (MCR) are both associated with adverse outcomes in older adults. Factors associated with MCR in CSVD remain poorly understood. We aime...
Plasma miR-34a-5p outperforms miR-126-3p in predicting cognitive decline in cerebral small vessel disease patients with impaired glucose regulation [0.03%]
血浆miR-34a-5p优于miR-126-3p可预测糖代谢异常的小血管疾病患者的认知衰退风险
Yanan Wang,Baoying Sun,Hui Li et al.
Yanan Wang et al.
Introduction: MicroRNAs (miRNAs) are promising biomarkers for the diagnosis and prognosis of neurodegenerative diseases. Over the past few years, miR-34a-5p and miR-126-3p have become some of the most characterized miRNA,...
Sustained attention in dementia with Lewy bodies: a task-based fMRI study [0.03%]
路易体痴呆的持续注意力缺陷：一项任务态功能磁共振成像研究
Davide Braghittoni,Greta Venturi,Lucia Guidi et al.
Davide Braghittoni et al.
Introduction: Patients with Dementia with Lewy Bodies (DLB) typically experience attentional deficits. Understanding these deficits and the underlying neural correlates is crucial as sustained attention supports higher le...
Transsynaptic complex dysfunction in the hippocampus of Alzheimer's disease patients [0.03%]
阿尔茨海默病患者海马区的跨突触复合体功能障碍
Ashly Hindle,Yong Chen,Xiangling Yin et al.
Ashly Hindle et al.
Introduction: Alzheimer's disease (AD) involves not only amyloid-β and tau pathology but synaptic dysfunction and impaired autophagy, though the underlying mechanisms and their relationship to AD progression are not well...