Exercise reduces the anxiogenic effects of meta-chlorophenylpiperazine: The role of 5-HT2C receptors in the bed nucleus of the stria terminalis [0.03%]
运动减少meta-氯苯基哌嗪的致焦虑效应：顶核中5-HT2C受体的作用
James H Fox,Melissa N Boucher,Khalil S Abedrabbo et al.
James H Fox et al.
Introduction: Two weeks of voluntary exercise in group-housed mice produces a reduction in anxiety-like behaviors across a number of different measures, including a reduction in the anxiety levels typically produced by th...
María Clara Gravielle,Leonardo Pignataro,Florence P Varodayan
María Clara Gravielle
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms [0.03%]
GRIN2B相关神经发育障碍的病理生理机制研究现状
Shasta L Sabo,Jessica M Lahr,Madelyn Offer et al.
Shasta L Sabo et al.
The GRIN2B-related neurodevelopmental disorder is a rare disease caused by mutations in the GRIN2B gene, which encodes the GluN2B subunit of NMDA receptors. Most individuals with GRIN2B-related neurodevelopmental disorder present with intel...
A review of the mechanisms underlying the role of the GIPC3 gene in hereditary deafness [0.03%]
GIPC3基因在遗传性耳聋中的作用机制研究进展及评述
Xinxin Li,Lin Shi,Liang Wang
Xinxin Li
The GAIP interacting protein c terminus (GIPC) genes encode a small family of proteins characterized by centrally located PDZ domains. GIPC3 encodes a 312 amino acid protein. Variants of human GIPC3 are associated with non-syndromic hearing...
Hey-Kyoung Lee
Hey-Kyoung Lee
Sensory loss leads to widespread adaptation of neural circuits to mediate cross-modal plasticity, which allows the organism to better utilize the remaining senses to guide behavior. While cross-modal interactions are often thought to engage...
Analytical approaches to examine gamma-aminobutyric acid and glutamate vesicular co-packaging [0.03%]
分析方法用于研究γ-氨基丁酸和谷氨酸的囊泡共包装情况
SeulAh Kim,Bernardo L Sabatini
SeulAh Kim
Multi-transmitter neurons, i.e., those that release more than one type of neurotransmitter, have been found in many organisms and brain areas. Given the peculiar biology of these cells, as well as the potential for diverse effects of each o...
The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction [0.03%]
钙调神经磷酸酶调节因子Sarah使果蝇的神经肌肉接头产生不同的稳态可塑性形式
Noah S Armstrong,C Andrew Frank
Noah S Armstrong
Introduction: The ability of synapses to maintain physiological levels of evoked neurotransmission is essential for neuronal stability. A variety of perturbations can disrupt neurotransmission, but synapses often compensate for disruptions ...
Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication [0.03%]
星形胶质细胞突触通讯中的环腺苷酸响应元件结合蛋白（CREB）转录因子
Jooyoung Kim,Bong-Kiun Kaang
Jooyoung Kim
Astrocytes are known to actively participate in synaptic communication by forming structures called tripartite synapses. These synapses consist of presynaptic axon terminals, postsynaptic dendritic spines, and astrocytic processes where ast...
Emma E Boxer,Jason Aoto
Emma E Boxer
Since the discovery of neurexins (Nrxns) as essential and evolutionarily conserved synaptic adhesion molecules, focus has largely centered on their functional contributions to glutamatergic synapses. Recently, significant advances to our un...
Diverse organization of voltage-gated calcium channels at presynaptic active zones [0.03%]
电压门控钙通道在前膜活性区的多样性组织结构
Weijia Zhang,He-Hai Jiang,Fujun Luo
Weijia Zhang
Synapses are highly organized but are also highly diverse in their organization and properties to allow for optimizing the computing power of brain circuits. Along these lines, voltage-gated calcium (CaV) channels at the presynaptic active ...