Harmen J Krugers,Casper C Hoogenraad
Harmen J Krugers
Humans and rodents retain memories for stressful events very well. The facilitated retention of these memories is normally very useful. However, in susceptible individuals a variety of pathological conditions may develop in which memories r...
Enhanced long-term microcircuit plasticity in the valproic Acid animal model of autism [0.03%]
丙戊酸自闭症动物模型中长期微环路可塑性的增强
Guilherme Testa Silva,Jean-Vincent Le Bé,Imad Riachi et al.
Guilherme Testa Silva et al.
A single intra-peritoneal injection of valproic acid (VPA) on embryonic day (ED) 11.5 to pregnant rats has been shown to produce severe autistic-like symptoms in the offspring. Previous studies showed that the microcircuitry is hyperreactiv...