Editorial: Regulation of AMPA receptors in brain diseases, from the genetic to the functional level, volume II [0.03%]
编辑部：脑疾病中AMPAR调节的遗传与功能机制（第二卷）
Laura Jiménez-Sánchez,Tak Pan Wong,Alberto Ouro
Laura Jiménez-Sánchez
Qi Wei Xu,Amanda Larosa,Tak Pan Wong
Qi Wei Xu
As a crucial player in excitatory synaptic transmission, AMPA receptors (AMPARs) contribute to the formation, regulation, and expression of social behaviors. AMPAR modifications have been associated with naturalistic social behaviors, such ...
Karri P Lamsa,Alfredo Kirkwood,P Jesper Sjöström
Karri P Lamsa
Friederike Steenken,Asli Pektaş,Christine Köppl
Friederike Steenken
Introduction: Age-related hearing difficulties have a complex etiology that includes degenerative processes in the sensory cochlea. The cochlea comprises the start of the afferent, ascending auditory pathway, but also rec...
Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis [0.03%]
Akap5将突触功能障碍与神经炎症信号联系起来以幼年型神经元 ceroid 淀粉样变病小鼠模型为例
Kevin P Koster,Zach Fyke,Thu T A Nguyen et al.
Kevin P Koster et al.
Palmitoylation and depalmitoylation represent dichotomic processes by which a labile posttranslational lipid modification regulates protein trafficking and degradation. The depalmitoylating enzyme, palmitoyl-protein thioesterase 1 (PPT1), i...
Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses [0.03%]
激活NMDAR后发育突触上NMDAR、CaMKII和AMPAR的快速顺序聚集
Yucui Chen,Shangming Liu,Ariel A Jacobi et al.
Yucui Chen et al.
Rapid, synapse-specific neurotransmission requires the precise alignment of presynaptic neurotransmitter release and postsynaptic receptors. How postsynaptic glutamate receptor accumulation is induced during maturation is not well understoo...
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity [0.03%]
无翼型平面细胞极性信号通路在最佳的活动依赖性的突触可塑性中是必不可少的
Carihann Dominicci-Cotto,Mariam Vazquez,Bruno Marie
Carihann Dominicci-Cotto
From fly to man, the Wingless (Wg)/Wnt signaling molecule is essential for both the stability and plasticity of the nervous system. The Drosophila neuromuscular junction (NMJ) has proven to be a useful system for deciphering the role of Wg ...
Participation of calcium-permeable AMPA receptors in the regulation of epileptiform activity of hippocampal neurons [0.03%]
钙通透型AMPA受体在海马神经元癫痫样活动中作用的研究
Valery Petrovich Zinchenko,Ilia Yu Teplov,Artem Mikhailovich Kosenkov et al.
Valery Petrovich Zinchenko et al.
Introduction: Epileptiform activity is the most striking result of hyperexcitation of a group of neurons that can occur in different brain regions and then spread to other sites. Later it was shown that these rhythms have...
Charlotte Piette,Nicolas Gervasi,Laurent Venance
Charlotte Piette
From the myriad of studies on neuronal plasticity, investigating its underlying molecular mechanisms up to its behavioral relevance, a very complex landscape has emerged. Recent efforts have been achieved toward more naturalistic investigat...
Per Jesper Sjöström
Per Jesper Sjöström