Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses [0.03%]
激活NMDAR后发育突触上NMDAR、CaMKII和AMPAR的快速顺序聚集
Yucui Chen,Shangming Liu,Ariel A Jacobi et al.
Yucui Chen et al.
Rapid, synapse-specific neurotransmission requires the precise alignment of presynaptic neurotransmitter release and postsynaptic receptors. How postsynaptic glutamate receptor accumulation is induced during maturation is not well understoo...
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity [0.03%]
无翼型平面细胞极性信号通路在最佳的活动依赖性的突触可塑性中是必不可少的
Carihann Dominicci-Cotto,Mariam Vazquez,Bruno Marie
Carihann Dominicci-Cotto
From fly to man, the Wingless (Wg)/Wnt signaling molecule is essential for both the stability and plasticity of the nervous system. The Drosophila neuromuscular junction (NMJ) has proven to be a useful system for deciphering the role of Wg ...
Participation of calcium-permeable AMPA receptors in the regulation of epileptiform activity of hippocampal neurons [0.03%]
钙通透型AMPA受体在海马神经元癫痫样活动中作用的研究
Valery Petrovich Zinchenko,Ilia Yu Teplov,Artem Mikhailovich Kosenkov et al.
Valery Petrovich Zinchenko et al.
Introduction: Epileptiform activity is the most striking result of hyperexcitation of a group of neurons that can occur in different brain regions and then spread to other sites. Later it was shown that these rhythms have...
Charlotte Piette,Nicolas Gervasi,Laurent Venance
Charlotte Piette
From the myriad of studies on neuronal plasticity, investigating its underlying molecular mechanisms up to its behavioral relevance, a very complex landscape has emerged. Recent efforts have been achieved toward more naturalistic investigat...
Per Jesper Sjöström
Per Jesper Sjöström
Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue [0.03%]
人细胞类型的独特的生物物理特征：来自神经外科切除脑组织研究的启示
Homeira Moradi Chameh,Madeleine Falby,Mandana Movahed et al.
Homeira Moradi Chameh et al.
Electrophysiological characterization of live human tissue from epilepsy patients has been performed for many decades. Although initially these studies sought to understand the biophysical and synaptic changes associated with human epilepsy...
Ben Yang,Roman A Romanov,Jinbin Xu et al.
Ben Yang et al.
Jung-Hwa Tao-Cheng,Sandra L Moreira,Christine A Winters et al.
Jung-Hwa Tao-Cheng et al.
The synaptic cleft is the extracellular part of the synapse, bridging the pre- and postsynaptic membranes. The geometry and molecular organization of the cleft is gaining increased attention as an important determinant of synaptic efficacy....
Clive R Bramham,Volkmar Lessmann,Anthony J Hannan et al.
Clive R Bramham et al.
Ana P Crestani,Ana Cicvaric,Adelaide P Yiu
Ana P Crestani