Analytical approaches to examine gamma-aminobutyric acid and glutamate vesicular co-packaging [0.03%]
分析方法用于研究γ-氨基丁酸和谷氨酸的囊泡共包装情况
SeulAh Kim,Bernardo L Sabatini
SeulAh Kim
Multi-transmitter neurons, i.e., those that release more than one type of neurotransmitter, have been found in many organisms and brain areas. Given the peculiar biology of these cells, as well as the potential for diverse effects of each o...
The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction [0.03%]
钙调神经磷酸酶调节因子Sarah使果蝇的神经肌肉接头产生不同的稳态可塑性形式
Noah S Armstrong,C Andrew Frank
Noah S Armstrong
Introduction: The ability of synapses to maintain physiological levels of evoked neurotransmission is essential for neuronal stability. A variety of perturbations can disrupt neurotransmission, but synapses often compensate for disruptions ...
Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication [0.03%]
星形胶质细胞突触通讯中的环腺苷酸响应元件结合蛋白（CREB）转录因子
Jooyoung Kim,Bong-Kiun Kaang
Jooyoung Kim
Astrocytes are known to actively participate in synaptic communication by forming structures called tripartite synapses. These synapses consist of presynaptic axon terminals, postsynaptic dendritic spines, and astrocytic processes where ast...
Emma E Boxer,Jason Aoto
Emma E Boxer
Since the discovery of neurexins (Nrxns) as essential and evolutionarily conserved synaptic adhesion molecules, focus has largely centered on their functional contributions to glutamatergic synapses. Recently, significant advances to our un...
Diverse organization of voltage-gated calcium channels at presynaptic active zones [0.03%]
电压门控钙通道在前膜活性区的多样性组织结构
Weijia Zhang,He-Hai Jiang,Fujun Luo
Weijia Zhang
Synapses are highly organized but are also highly diverse in their organization and properties to allow for optimizing the computing power of brain circuits. Along these lines, voltage-gated calcium (CaV) channels at the presynaptic active ...
The biological alterations of synapse/synapse formation in sepsis-associated encephalopathy [0.03%]
脓毒症相关性脑病突触/突触形成发生的生物改变
Chuan Tang,Ye Jin,Huan Wang
Chuan Tang
Sepsis-associated encephalopathy (SAE) is a common complication caused by sepsis, and is responsible for increased mortality and poor outcomes in septic patients. Neurological dysfunction is one of the main manifestations of SAE patients. P...
Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo [0.03%]
筐蛋白抑制剂Pitstop-2对体内中枢突触的突触小泡循环的影响
Alp Paksoy,Simone Hoppe,Yvette Dörflinger et al.
Alp Paksoy et al.
Four modes of endocytosis and subsequent synaptic vesicle (SV) recycling have been described at the presynapse to ensure the availability of SVs for synaptic release. However, it is unclear to what extend these modes operate under physiolog...
Serotonin as a volume transmission signal in the "simple nervous system" of mollusks: From axonal guidance to behavioral orchestration [0.03%]
甲壳类动物"简单神经系统"中的血清素作为容积传输信号：从轴突引导到行为协调
Elena E Voronezhskaya
Elena E Voronezhskaya
Membrane lipid rafts are required for AMPA receptor tyrosine phosphorylation [0.03%]
膜脂筏对AMP阿酸盐受体酪氨酸磷酸化是必需的
Takashi Hayashi
Takashi Hayashi
Membrane lipid rafts are sphingolipids and cholesterol-enriched membrane microdomains, which form a center for the interaction or assembly of palmitoylated signaling molecules, including Src family non-receptor type protein tyrosine kinases...
Neocortical layer 5 subclasses: From cellular properties to roles in behavior [0.03%]
新皮层第5亚类：从细胞特性到行为中的作用
Sara Moberg,Naoya Takahashi
Sara Moberg
Layer 5 (L5) serves as the main output layer of cortical structures, where long-range projecting pyramidal neurons broadcast the columnar output to other cortical and extracortical regions of the brain. L5 pyramidal neurons are grouped into...