Fertility in non-classic lipoid CAH - A case report and review of the literature [0.03%]
非典型类固醇生成障碍性脂质CAH的生育能力：一例病例报告及文献回顾
Emre Murat Altinkilic,Camilla Mains Balle,Clarissa Daniela Voegel et al.
Emre Murat Altinkilic et al.
Introduction: Non-classic lipoid congenital adrenal hyperplasia (LCAH) presents with adrenal insufficiency but typically lacks a gonadal phenotype or features a delayed-onset gonadal presentation. Information on fertility...
Case Reports
Hormone research in paediatrics. 2025 Mar 10:1-15. DOI:10.1159/000545063 2025
Elpis Athina Vlachopapadopoulou
Elpis Athina Vlachopapadopoulou
Background: Obesity, long viewed as a reversible outcome of personal choices, is influenced by a complex interplay of genetic, physiological, socioeconomic, and environmental factors A special group of children and adoles...
A novel variant in an intron splicing enhancer associated with familial growth hormone deficiency [0.03%]
与家族性生长激素缺乏相关的内含子剪接增强子中的新变异
Sally Radovick,Mariam Gangat,Bethany Murphy et al.
Sally Radovick et al.
Introduction: Variants in the intron splicing enhancer (ISE) of intron 3 in the GH1 gene are implicated in the etiology of isolated growth hormone deficiency Type 2 (Type II IGHD). ...
Children with Growth Hormone Deficiency Treated With Lonapegsomatropin Demonstrated Sustained Height Improvements for up to 6 Years- enliGHten Trial Final Results [0.03%]
使用Lonapegsomatropin治疗生长激素缺乏症儿童可长达6年的持续身高改善-enliGHten试验最终结果
Aristides K Maniatis,Paul S Thornton,Ulhas M Nadgir et al.
Aristides K Maniatis et al.
Background: This international, Phase 3, open-label extension trial evaluated the long-term safety and efficacy of once-weekly lonapegsomatropin in children with growth hormone deficiency (GHD). ...
Optimal Low Dose Synacthen Stimulation Test Sampling Time for Diagnosis of Adrenal Insufficiency Using Monoclonal Antibody Immunoassay [0.03%]
使用单克隆抗体免疫测定诊断肾上腺功能不全的最佳小剂量合贝特刺激试验采样时间
Busra Gurpinar Tosun,Serap Turan,Goncagul Haklar et al.
Busra Gurpinar Tosun et al.
Context: The low-dose synacthen stimulation test (LDSST) evaluates hypothalamo-pituitary-adrenal axis function. However, studies on the correlation between morning basal and stimulated cortisol concentrations using specif...
Published Erratum
Hormone research in paediatrics. 2025 Feb 28:1. DOI:10.1159/000543580 2025
Prolonged Pubertal Suppression due to Retained Histrelin Implant in Three Children with Central Precocious Puberty [0.03%]
中枢性性早熟儿童体内埋植剂残留导致的长时间抑制青春期发育
Ian Marpuri,Mitchell E Geffner,Lily C Chao
Ian Marpuri
Introduction Histrelin acetate implant (HI) is an approved treatment option for children with central precocious puberty. Implant duration has been reported to surpass the recommended replacement interval of 1 to 2 years. Implant breakage i...
Case Reports
Hormone research in paediatrics. 2025 Feb 27:1-8. DOI:10.1159/000544181 2025
Unveiling the Link: Obesity, Diet, Hypothalamic Inflammation and Central Precocious Puberty - Recent Insights and Implications [0.03%]
肥胖、饮食、下丘脑炎症和中枢性性早熟之间的联系--最近的见解及意义
Galateia Stathori,Anastasia-Maria Tzounakou,Nikolaos F Vlahos et al.
Galateia Stathori et al.
Background: Childhood obesity is on the rise globally, raising concerns among the medical community. The phenomenon is closely linked to high-fat diets. Concurrently, the prevalence of Central Precocious Puberty (CPP) is ...
Familial Non-autoimmune Hyperthyroidism Caused by an Extracellular Domain Variant (p.Leu267Phe) of the TSH Receptor [0.03%]
由TSH受体的细胞外结构域突变(p.Leu267Phe)导致的家庭性非自身免疫性甲亢
Kazuhiro Shimura,Yosuke Ichihashi,Kiyomi Abe et al.
Kazuhiro Shimura et al.
Introduction: Non-autoimmune hyperthyroidism (NAH) is a rare genetic disorder caused by germline activating variants in the TSH receptor (TSHR) gene. While most NAH-related TSHR variants are located in the seven-transmemb...