Double trouble: When focal and diffuse hyperinsulinism occur simultaneously [0.03%]
双管齐下：当中心性和弥散性高胰岛素血症同时发生时
Victoria R Sanders,Katherine Lord,Winnie Sigal et al.
Victoria R Sanders et al.
Introduction Congenital hyperinsulinism (HI) may be diazoxide-responsive or diazoxide-unresponsive. Patients with diazoxide-unresponsive HI are further classified based on having the diffuse or focal form of the disease, with different mana...
Case Reports
Hormone research in paediatrics. 2026 Mar 8:1-15. DOI:10.1159/000550909 2026
Prediabetes and Type 2 Diabetes in Youth Following Premature Adrenarche [0.03%]
青春期前肾上腺初现与青少年时期的糖尿病前期和2型糖尿病的关系
Varsha Thomas,Natalie Segev,Amy S Shah et al.
Varsha Thomas et al.
Introduction: Type 2 diabetes mellitus (T2DM) is more aggressive when diagnosed in childhood, and its incidence continues to rise. Premature adrenarche (PA) is often considered benign; however, emerging data suggest a com...
Autoantibody positive versus autoantibody negative type 1 diabetes in children: clinical and biochemical characteristics [0.03%]
儿童自身抗体阳性与自身抗体阴性1型糖尿病的临床及生化特点
Roos I van Rhijn,A S Paul van Trotsenburg,Rosaline Mentink
Roos I van Rhijn
Introduction: This study aimed to investigate differences in clinical and biochemical characteristics between autoantibody positive and autoantibody negative type 1 diabetes mellitus (T1DM) in children, to get a better un...
Once-weekly Lonapegsomatropin was Efficacious and Well Tolerated in Chinese Children with Growth Hormone Deficiency: Results from a Phase 3 Randomized Trial [0.03%]
一项一期随机试验：一周一次的Lonapegsomatropin用于治疗生长激素缺乏症儿童疗效显著且耐受性良好
Yanqin Ying,Haiyan Wei,Yan Zhong et al.
Yanqin Ying et al.
Introduction: Lonapegsomatropin, a prodrug of somatropin, is approved for once-weekly treatment of paediatric growth hormone deficiency (GHD) in the USA and Europe. Here, we report the first trial to assess the efficacy a...
Sixteen Years of Clinical Data Including Genetic Analysis to Explain Delayed Puberty in a Chinese Boy with 21-Hydroxylase Deficiency: A Case Report [0.03%]
遗传分析解释中国一例21-羟化酶缺乏男孩青春期延迟的16年临床资料
Xinmeng Wang,Zheng Yuan,Miao Qin et al.
Xinmeng Wang et al.
Introduction: In 21-hydroxylase deficiency (21-OHD), impaired 21-hydroxylase activity causes 17-hydroxyprogesterone (17-OHP) accumulation and androgen excess, typically manifesting as hyperandrogenism. The POR gene encode...
Case Reports
Hormone research in paediatrics. 2026 Feb 26:1-17. DOI:10.1159/000551139 2026
European Society for Paediatric Endocrinology and European Society of Endocrinology Joint Clinical Practice Guidance for Healthcare Transition from Paediatric to Adult Endocrine Care [0.03%]
欧洲儿科内分泌学会和欧洲内分泌学会联合临床实践指导：从儿童到成人内分泌护理的医疗过渡
Enora Le Roux,Kirstine Stochholm,Martin Fassnacht et al.
Enora Le Roux et al.
Background: The transition from paediatric to adult healthcare is a critical period for young individuals with endocrine conditions. Despite numerous published recommendations, Europe still lacks recent, comprehensive, ev...
Practice Guideline
Hormone research in paediatrics. 2026 Feb 19:1-11. DOI:10.1159/000550744 2026
Assessment of combined growth hormone and gonadotropin-releasing hormone analogue treatment in children with Silver-Russell syndrome [0.03%]
生长激素联合促性腺激素释放激素类似物治疗银-Russell综合征患儿的疗效评估
Amelie Perriere,Frédéric Brioude,Marie-Noëlle Dufourg et al.
Amelie Perriere et al.
Objective: Silver-Russell syndrome (SRS) is a rare imprinting disorder characterized by growth retardation, early puberty, and poor pubertal growth, leading to short stature. We aimed to assess the outcome in terms of adu...
Long-term growth hormone therapy improves adult height in children with Indian hedgehog (IHH)-related short stature [0.03%]
长效生长激素治疗可改善印度豪猪(IHH)相关矮小症儿童的成人身高
Joaquim de Matos Cavalcante,Laurana de Polli Cellin,Amanda Latuffe Soares Damião et al.
Joaquim de Matos Cavalcante et al.
Context: Evidence for growth hormone therapy in Indian hedgehog (IHH)-related short stature is limited. Objective: To assess growth out...
Decreased Gross Motor, Working Memory, and Adaptive Behavior in Children with Congenital Adrenal Hyperplasia [0.03%]
先天肾上腺皮质增生症患儿的大运动、工作记忆和适应行为降低
Nozomi L Yamashita,Edwin A Deras,Sharon H O Apos Neil et al.
Nozomi L Yamashita et al.
Introduction: Youth and adults with classical congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) are at risk for cognitive deficits and brain structural changes. Although factors inherent to CAH...
Testing Multiple Delivery Methods of the Virtual Exercise Games for Youth with T1D (ExerT1D) Peer Intervention: Protocol Development and Feasibility [0.03%]
针对T1D青年进行虚拟锻炼游戏（ExerT1D）同伴干预的多种交付方法测试：协议开发与可行性研究
Garrett I Ash,Soohyun Nam,Selene S Mak et al.
Garrett I Ash et al.
Background: Adolescents with type 1 diabetes (T1D) face barriers to moderate-to-vigorous physical activity (MVPA) such as uncertainty with self-management, limited access to supportive environments, and stigma related to ...