Effect of puberty suppression and gender affirming hormone treatment depends upon prior extent of pubertal development in young transgender adolescents [0.03%]
青春期阻抑和性别确认激素治疗的效果取决于年轻跨性别青少年先前的青春期发育程度
Pierluigi Diana,Kirpal Adu-Gyamfi,Gary Butler
Pierluigi Diana
Background: It is not known whether the extent of pubertal development influences the treatment effects in very young transgender people undergoing puberty suppression (PS) and gender-affirming hormone therapy (GAHT). Thi...
Short stature and response to growth hormone treatment in CUL3-related neurodevelopmental disorder [0.03%]
CUL3相关神经发育障碍的身材矮小和生长激素治疗反应
Petra Loid,Anu Närhi,Shabir Hussain et al.
Petra Loid et al.
Introduction Recent research has expanded the spectrum of genetic causes for growth failures. Patients with CUL3-related neurodevelopmental disorder (NDD) present with variable phenotypic manifestations and growth retardation has been obser...
Case Reports
Hormone research in paediatrics. 2025 Aug 5:1-11. DOI:10.1159/000547715 2025
A Scoping Review of Literature Exploring the Healthcare Transition of Individuals with Congenital Adrenal Hyperplasia [0.03%]
关于探究先天性肾上腺皮质增生患者医疗过渡的文献综述
Leslie Pitts,Alexandra Armstrong,Louise Fleming et al.
Leslie Pitts et al.
Background: Despite guidelines emphasizing the importance of a structured pediatric-to-adult healthcare transition (HCT) for individuals with congenital adrenal hyperplasia (CAH), significant gaps remain in understanding ...
Acquired Generalized Lipodystrophy with Extensive Autoimmune Involvement: A Case Report and Review of the Literature [0.03%]
获得性广泛自身免疫损伤的全身性脂肪营养不良症一例及文献复习
Asma Deeb,Rasha Hassan Beck,Umama Fatima et al.
Asma Deeb et al.
Introduction: Acquired generalized lipodystrophy (AGL) is a rare condition characterized by body fat loss and, usually, metabolic syndrome with or without associated autoimmune diseases. Clinical phenotypes of AGL are het...
Case Reports
Hormone research in paediatrics. 2025 Aug 4:1-19. DOI:10.1159/000547714 2025
Finding early biomarkers to prevent unfavorable long-term health outcomes after premature adrenarche - a multicenter prospective cohort study protocol [0.03%]
一项多中心前瞻性队列研究方案：寻找早期生物标志物以预防早初肾上腺皮质功能亢进症带来的不良长期健康结局
Philipp Augsburger,Oili Niskanen,Jarmo Jääskeläinen et al.
Philipp Augsburger et al.
Introduction Adrenarche is a pre-pubertal developmental phase in humans characterized by increasing levels of adrenal androgens in circulation. While its regulation and biological significance remain poorly understood, the earlier onset of ...
Novel Insights into the Pathophysiology and Management of Obesity in Childhood and Adolescence [0.03%]
儿童和青少年肥胖的病理生理及管理的新见解
Evangelia Charmandari,Sabine E Hannema,Evelien F Gevers
Evangelia Charmandari
A growth prediction model from mid-puberty to near adult height in adolescents with idiopathic isolated growth hormone deficiency treated with growth hormone [0.03%]
儿童生长激素缺乏症的生长预测模型——从青春期中期到接近成人身高
Joeri Vliegenthart,Maria A J de Ridder,Jan Maarten Wit et al.
Joeri Vliegenthart et al.
Introduction Recombinant human growth hormone (rhGH) treatment of children with idiopathic isolated growth hormone deficiency (IIGHD) typically results in catch-up growth for several years followed by a period of normal growth. The effect o...
The Effect of Childhood Obesity on Growth: Interpretation of Growth-Hormone Provocation Tests [0.03%]
儿童肥胖对生长的影响：生长激素激发试验的结果解读
Feneli Karachaliou,Jouly Maltezou,Vassiliki Bekiou et al.
Feneli Karachaliou et al.
Background: Obesity during childhood can significantly impact growth and puberty Summary Obese children show accelerated linear growth during pre-puberty possibly due to early estrogenization, normal /high IGF1 levels, hi...
An unusual liver and kidney involvement in congenital hyperinsulinism with HNF1A mutation: a case report [0.03%]
HNF1A突变的先天性高胰岛素血症伴肝肾异常一例报告
Evelina Maines,Arianna Maiorana,Maria Chiara Cardellini et al.
Evelina Maines et al.
Background Hepatocyte nuclear factor-1α (HNF-1α) and hepatocyte nuclear factor-4α (HNF-4α) are transcription factors highly expressed in β-cells, hepatocytes, intestinal epithelial cells, and renal tubular cells. Variants in both genes...
Case Reports
Hormone research in paediatrics. 2025 Jul 3:1-16. DOI:10.1159/000547127 2025