David Ermert,Constantin F Urban,Britta Laube et al.
David Ermert et al.
Neutrophil extracellular traps (NETs) play an important role in innate immunity to microbial infections. NETs have been described in several species, but the molecular details of NET formation and their role in infection has not been addres...
Neutrophil extracellular traps: a strategic tactic to defeat pathogens with potential consequences for the host [0.03%]
中性粒细胞胞外陷阱：一种通过潜在影响宿主健康的手段来战胜病原体的策略
Eva Medina
Eva Medina
Recent investigations have highlighted new roles for neutrophils in the biology of infection and inflammation. Neutrophils are one of the main players in the innate immune system and actively contribute to host defense by killing pathogens....
Beyond the NETs [0.03%]
网外之网
Eva Medina
Eva Medina
SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: an example of fine specificity in microbial ligand recognition by innate immune receptors [0.03%]
甘露糖结合凝集素受体、TLRs与脑膜炎奈瑟氏菌表层蛋白的相互作用：先天性免疫受体对微生物配基识别的一个特异性的例子
Annette Plüddemann,Subhankar Mukhopadhyay,Marko Sankala et al.
Annette Plüddemann et al.
Macrophages express various classes of pattern recognition receptors involved in innate immune recognition of artificial, microbial and host-derived ligands. These include the scavenger receptors (SRs), which are important for phagocytosis,...
Manno(rhamno)biose-containing capsular polysaccharides of Klebsiella pneumoniae enhance opsono-stimulation of human polymorphonuclear leukocytes [0.03%]
肺炎克雷伯菌甘露-(鼠李)-双糖荚膜多糖增强其对人多形核白细胞的调理体外刺激作用
Hany Sahly,Yona Keisari,Itzhak Ofek
Hany Sahly
We tested the relationship between the capsular and the O-antigen structures and the ability of bacteria to trigger respiratory burst in human polymorphonuclear leukocytes (PMNL). Capsulated and non-capsulated variants as well as capsule-sw...
Role of intestinal mucins in innate host defense mechanisms against pathogens [0.03%]
肠黏蛋白在防御病原菌先天免疫机制中的作用
Poonam Dharmani,Vikas Srivastava,Vanessa Kissoon-Singh et al.
Poonam Dharmani et al.
Gastrointestinal mucins produced by goblet cells comprise the main structural components of the mucus layer. Mucins play a critical role in the maintenance of mucosal homeostasis and are responsible for the differential effector and regulat...
Degradation of human alpha- and beta-defensins by culture supernatants of Porphyromonas gingivalis strain 381 [0.03%]
牙龈卟啉单胞菌菌株381培养上清液对人α-和β-防御素的降解作用
M D Carlisle,R N Srikantha,K A Brogden
M D Carlisle
Porphyromonas gingivalis produces proteases capable of degrading cytokines, host heme proteins and some antimicrobial peptides. In this study, we show that P. gingivalis culture supernatants fully or partially degrade human neutrophil pepti...
High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism [0.03%]
牙龈卟啉单胞菌高分子量GINGIPAIN通过非蛋白水解机制诱导人类巨噬细胞样细胞的细胞因子反应
Rebecca E Fitzpatrick,Andrea Aprico,Lakshmi C Wijeyewickrema et al.
Rebecca E Fitzpatrick et al.
Periodontal disease is an oral inflammatory disease affecting the supporting structures of teeth. Porphyromonas gingivalis, a major pathogenic agent for the disease, expresses a number of virulence factors, including cysteine proteases call...
A new pathway of staphylococcal pathogenesis: apoptosis-like death induced by Staphopain B in human neutrophils and monocytes [0.03%]
金黄色葡萄球菌诱导人类中性粒细胞和单核细胞凋亡样死亡的新途径：由Staphopain B介导
Jan Smagur,Krzysztof Guzik,Lukasz Magiera et al.
Jan Smagur et al.
Circulating neutrophils and monocytes form the first line of cellular defense against invading bacteria. Here, we describe a novel and specific mechanism of disabling and eliminating phagocytes by Staphylococcus aureus. Staphopain B (SspB) ...
Heiko Herwald,Arne Egesten
Heiko Herwald