Implementing Genomic Medicine in a Federally Qualified Health Center: Assessing Readiness through a Mixed-Methods Approach [0.03%]
基于混合研究方法的联邦合格医疗中心实施基因组医学的准备度评估模型
Emory William Heffernan,Paramita Das,Larry Hearld et al.
Emory William Heffernan et al.
Introduction: Genomic medicine enables early detection of treatable conditions and supports personalized care across all populations; however, evidence guiding its implementation in resource-constrained healthcare setting...
The Path to Screening US Newborns for Severe Combined Immunodeficiency, 1968-2018: A Narrative Review of a Successful Biomedical Research and Public Health Partnership [0.03%]
美国新生儿严重联合免疫缺陷筛查之路（1968～2018）：一次临床研究与公共卫生合作的成功案例——叙述性文献回顾
Scott D Grosse,Robert F Vogt,Golriz K Yazdanpanah et al.
Scott D Grosse et al.
Background: Newborn screening for severe combined immunodeficiency (SCID) represents an important advancement in public health genomics as the first DNA-based primary screening test in newborn screening programs. The stor...
A value-based evaluation framework for guiding the adoption and scale-up of cancer genomics interventions [0.03%]
基于价值的评估框架，指导癌症基因组学干预措施的采用和扩大规模
Gerard Solís-Díez,Claudia Prats,Victòria Valls-Comamala et al.
Gerard Solís-Díez et al.
Introduction Cancer imposes a substantial burden characterized by high morbidity and mortality, reduced quality of life, and increased healthcare costs. This burden is expected to rise due to aging populations and persistent exposure to ris...
Single Nucleotide Polymorphisms in Orexin-1 and BDNF Receptor Genes are Associated with Increased Risk of Developing Post-Partum Depression among Women with Gestational Diabetes Mellitus [0.03%]
与妊娠糖尿病女性发生产后抑郁症风险增加相关的食欲素1和脑源性神经营养因子受体基因单核苷酸多态性关联的研究
Pasha Ghazal,Shanza Tariq,Tehniyat Munshi
Pasha Ghazal
Objectives: In this study, association between GDM and risk of developing PPD was investigated and risk factors for PPD were identified using the gold-standard Edinburgh Post natal Depression Scale (EPDS). Evidence sugges...
Implementation of the National Collegiate Athletic Association (NCAA) Sickle Cell Trait Screening Policy: Methods and Staff and Athlete Perspectives [0.03%]
美国高校体育协会实施镰状细胞性状筛查政策的方法以及工作人员和运动员的视角
Kristen L Kucera,Robert P Agans,Paul A Robbins et al.
Kristen L Kucera et al.
Introduction: This paper describes methods for a national study evaluating the implementation of the National Collegiate Athletic Association's (NCAA) policy on sickle cell trait (SCT) screening of athletes and describes ...
Sex-Specific Diagnostic Inequality in Fabry Disease: Lessons Learned from Analysis of Newborn Screening and Cascade Testing in Tennessee from 2017 to 2024 [0.03%]
从2017年到2024年田纳西州新生儿筛查和队列检测中学习到的弗莱特病诊断不平等的经验：性别差异分析
Yutaka Furuta,Neena S Agrawal,Natalie N Owen et al.
Yutaka Furuta et al.
Introduction: Fabry disease (FD) is an X-linked lysosomal storage disease caused by alpha-galactosidase A (aGAL) deficiency. Newborn screening (NBS) programs for FD have been implemented in several U.S. states; however, i...
Beyond the Flush: Reframing ALDH2 deficiency as a public health risk [0.03%]
超越传统的治疗观念：将ALDH2缺陷重新定义为公共卫生风险
Jennifer L Young,Fiona Seung
Jennifer L Young
What Makes Families SHARE: The family communication environments of disseminators and non-disseminators of family cancer history [0.03%]
中国家庭交流环境下的家族癌症病史传播机制研究
Danyel I Smith,Beverly Estrada Balcarcel,Raegan Bishop et al.
Danyel I Smith et al.
Background: Family Cancer History (FCH) provides insight into cancer risk and can guide prevention efforts. Black Americans experience high cancer burden and report several barriers to FCH knowledge due to family communic...
Health Literacy and Awareness of Family Health History in the All of Us Research Program [0.03%]
“全民参与研究计划”中的健康素养与家庭病史意识
Jemar R Bather,Melody S Goodman,Stephanie H Cook et al.
Jemar R Bather et al.
We quantified the association between health literacy and awareness of family health history using a nationwide cross-sectional study of 286,293 All of Us Research Program participants. Awareness of family health history was constructed as ...
Aaron Eli Segal,Xiaobai Li,David Wendler
Aaron Eli Segal
Background: In current practice, individuals rarely share in the profits of research using their biospecimens. Many commentators defend this practice on the grounds that the contributions donors make are not important eno...