Reconceptualizing bipolar disorder through an integrative biological lens: synthesis, convergence, and emerging directions [0.03%]
通过整合生物学视角对双相障碍进行再概念化:综合、趋同和新兴方向
Yasin Ali Muhammad
Yasin Ali Muhammad
Bipolar disorder (BD) is a highly complex, chronic psychiatric illness marked by episodic disturbances of mood. While historically conceptualized as a disorder of neurotransmitter imbalance, converging evidence suggests it is better underst...
Persistent Afferent Bias: a mechanistic link between somatic disruption and autonomic dysregulation [0.03%]
持续的传入偏差:躯体干扰与自主神经失调之间的机制联系
Boris Živný
Boris Živný
Persistent Afferent Bias (PAB) represents a state-dependent alteration in sensory weighting through which Somatic Disruption influences Autonomic Regulation. While the classical concept of the facilitated spinal segment provided an early ne...
Integrative perspectives on electroacupuncture modulation of vagal-cholinergic and neuro-immune-metabolic regulation in long COVID [0.03%]
整合电针调节迷走神经-胆碱能及神经-免疫-代谢在长新冠中的作用机制研究
Liwen Wang,Xiaoyang Hu,Dongning Yan
Liwen Wang
Long COVID is increasingly recognized as a multisystem condition involving persistent inflammation, autonomic dysregulation, and metabolic disturbance. The vagus nerve-mediated cholinergic anti-inflammatory pathway (CAP) provides a biologic...
Fatigue relief is possible [0.03%]
缓解疲劳或有可能
M De Ventura,G Mattioni,T LAbbate et al.
M De Ventura et al.
Chronic fatigue is widely discussed across clinical and non-clinical contexts, yet its definition and measurement remain heterogeneous and debated. In this fragmented landscape, adopting an efficacy-informed perspective grounded in mitigati...
Progress and ongoing conceptual challenges "on the way to integrative human neuroscience"-ten years after [0.03%]
迈向整合人脑神经科学的进展及概念挑战——十年后的思考
Felix Tretter,Henriette Löffler-Stastka,Hans Albert Braun et al.
Felix Tretter et al.
Ten years ago, we published a position paper in this journal, criticizing reductionist claims of neurobiology related to mental disorders and important theoretical concepts like free will. Our interdisciplinary group of experts highlighted ...
Consciousness emerges from temporal integration across biological scales: from cellular memory to phenomenological experience [0.03%]
意识源于生物学尺度上的时间整合:从细胞记忆到现象学体验
Alfredo López Parra
Alfredo López Parra
Consciousness remains one of the central challenges in contemporary neuroscience, in part due to the absence of an explicit framework describing the temporal constraints required for integrative processing. While influential models such as ...
High serum uric acid levels explains the negative impact of the altitude adaptation index on the brain electroencephalographic Microstate D under high-altitude hypoxic conditions [0.03%]
高血尿酸水平解释了高原低氧环境下高原适应指数对大脑电生理微状态D的负面影响
Jie Xu,Shurong Jia,Yongjun Jing et al.
Jie Xu et al.
Objective: To explore the mediating role of serum uric acid (SUA) in the relationship between the acclimatization/adaptation index (AAI) and the transition probability of electroencephalographic (EEG) Microstate D within ...
Synergistic efficacy of combined neurolysis and methylcobalamin in peripheral nerve injury: a randomized clinical trial [0.03%]
神经溶解联合甲钴胺治疗周围神经损伤的协同疗效研究:随机对照试验
Xuwei Hu,Zuoshi Li
Xuwei Hu
Introduction: Peripheral nerve injury (PNI) imposes significant burdens, requiring therapies targeting both mechanical compression and inflammatory pathophysiology. While neurolysis addresses extrinsic compression and met...
The nucleus tractus solitarii across vertebrates: developmental origins, comparative organization, and supranuclear modulation in humans [0.03%]
脊椎动物孤束核的发育起源、比较组织和人类的脑区调节机制
Yong-Shin Hong,Young-Seok Park
Yong-Shin Hong
The nucleus tractus solitarii (NTS) is a highly conserved brainstem structure that has served as a principal hub for visceral sensory integration across vertebrate evolution. While the NTS has long been described as a relay for cardiovascul...
Somato-Psychic Pathway: a universal developmental trajectory linking somatic structural-functional integrity, autonomic regulation, and the emergence of mind [0.03%]
身心路径:将躯体结构-功能完整性、自主神经调控和心智出现联系起来的普遍发展轨迹
Boris Živný
Boris Živný
The Somato-Psychic Pathway (SPP) is proposed as a universal ontogenetic developmental trajectory through which somatic structural-functional integrity and autonomic regulation shape the emergence and stability of the mind under both physiol...