Distinct neuronal processes in the ventromedial prefrontal cortex mediate changes in attention load and nicotine pro-cognitive effects in male rats [0.03%]
雄性大鼠腹内侧前额皮质中不同的神经元过程介导注意力负荷变化及尼古丁促认知效应
Caroline Vouillac-Mendoza,Nathalie Biendon,Sandra Dovero et al.
Caroline Vouillac-Mendoza et al.
The prefrontal cortex (PFC) plays a key role in attention. In particular, neuronal activity in the ventromedial PFC (vmPFC) has been implicated in the preparatory attentional period that immediately precedes cue presentation. However, wheth...
Hiroyuki Miyamoto,Emi Mazaki,Yuichi Makino et al.
Hiroyuki Miyamoto et al.
Experience-dependent neural plasticity enables the brain to adapt to diverse and dynamic environments by reshaping circuits. In the adult visual system, this plasticity can be elicited by repeated sensory stimuli; however, its temporal dyna...
Optogenetics and chemogenetics: key tools for modulating neural circuits in rodent models of depression [0.03%]
光遗传学和化学遗传学：调节抑郁动物模型神经回路的关键工具
Shaowei Li,Jianying Zhang,Jiehui Li et al.
Shaowei Li et al.
Optogenetics and chemogenetics are emerging neuromodulation techniques that have attracted significant attention in recent years. These techniques enable the precise control of specific neuronal types and neural circuits, allowing researche...
Early-life stress differentially affects CA3 synaptic inputs converging on apical and basal dendrites of CA1 pyramidal neurons [0.03%]
早期生活压力对CA1锥体神经元树突状细胞的顶端和基底树突的CA3突触输入产生不同的影响
David Jappy,Rostislav Sokolov,Yulia Dobryakova et al.
David Jappy et al.
There is evidence that stress factors and negative experiences in early in life may affect brain development leading to mental disorders in adulthood. At the early stage of postnatal ontogenesis, the central nervous system has high plastici...
Activity-dependent synaptic competition and dendrite pruning in developing mitral cells [0.03%]
发育中的有活动依赖性的突触竞争和树突修剪米塔尔细胞
Takeshi Imai
Takeshi Imai
During the early postnatal period, neurons in sensory circuits dynamically remodel their connectivity to acquire discrete receptive fields. Neuronal activity is thought to play a central role in circuit remodeling during this period: Neuron...
Mylène Wilt,Robin Magnard,Sebastien Carnicella et al.
Mylène Wilt et al.
Electrical stimulation of the sciatic nerve restores inspiratory diaphragm function in mice after spinal cord injury [0.03%]
电刺激坐骨神经可使脊髓损伤小鼠的膈肌呼吸功能恢复
Ian Walling,Sarah Baumgartner,Mitesh Patel et al.
Ian Walling et al.
Introduction: Spinal cord injury in the high cervical cord can impair breathing due to disruption of pathways between brainstem respiratory centers and respiratory motor neurons in the spinal cord. Electrical stimulation ...
Neural activity responsiveness by maturation of inhibition underlying critical period plasticity [0.03%]
皮层抑制的成熟决定关键时期的神经元活动可塑性上限
Ibuki Matsumoto,Sou Nobukawa,Takashi Kanamaru et al.
Ibuki Matsumoto et al.
Introduction: Neural circuits develop during critical periods (CPs) and exhibit heightened plasticity to adapt to the surrounding environment. Accumulating evidence indicates that the maturation of inhibitory circuits, su...
Hyaluronidase-induced matrix remodeling contributes to long-term synaptic changes [0.03%]
透明质酸酶诱导的基质重塑有助于长期突触变化
Rostislav Sokolov,Viktoriya Krut&#x;,Vsevolod Belousov et al.
Rostislav Sokolov et al.
Extracellular brain space contains water, dissolved ions, and multiple other signaling molecules. The neural extracellular matrix (ECM) is also a significant component of the extracellular space. The ECM is synthesized by neurons, astrocyte...
Evidence for direct dopaminergic connections between substantia nigra pars compacta and thalamus in young healthy humans [0.03%]
关于年轻健康人大脑黑质致密部和丘脑之间直接多巴胺能联系的证据
Giovanni Cirillo,Giuseppina Caiazzo,Federica Franza et al.
Giovanni Cirillo et al.
The substantia nigra pars compacta (SNc), one of the main dopaminergic nuclei of the brain, exerts a regulatory function on the basal ganglia circuitry via the nigro-striatal pathway but its possible dopaminergic innervation of the thalamus...