Summary statistics of learning link changing neural representations to behavior [0.03%]
转换神经表示到行为的学习链接的摘要统计学数据
Jacob A Zavatone-Veth,Blake Bordelon,Cengiz Pehlevan
Jacob A Zavatone-Veth
How can we make sense of large-scale recordings of neural activity across learning? Theories of neural network learning with their origins in statistical physics offer a potential answer: for a given task, there are often a small set of sum...
Clustered architecture of ipsilateral and interhemispheric connections in macaque ventrolateral prefrontal cortex [0.03%]
猕猴外侧前额叶皮层同侧和跨半球连接的模块化架构
Danling Hu,Hangqi Li,Toru Takahata et al.
Danling Hu et al.
The fine-scale organization of intrinsic and extrinsic connections in the primate ventrolateral prefrontal cortex (VLPFC), a region essential for higher cognitive functions, remains poorly understood. This contrasts with, for example, the w...
Spike-timing-dependent plasticity offers delay-gated oscillatory potentiation for autaptic weights [0.03%]
基于脉冲时间依赖可塑性的自突触权重振荡增强的延迟门控机制
Risa Onda,Mihoko Ishida,Kouhei Hattori et al.
Risa Onda et al.
Neuronal networks in animal brains are considered to realize specific filter functions through the precise configuration of synaptic weights, which are autonomously regulated without external supervision. In this study, we employ a single H...
How perceptual learning rewires brain connectivity: lessons from the visual system in a top-down perspective [0.03%]
从顶层视角看感知学习如何重构脑连接性：视觉系统的启示
Alan Consorti,Alessandro Sale
Alan Consorti
Neural circuits sculpt their structure and modify the strength of their connections to effectively adapt to the external stimuli throughout life. In response to practice and experience, the brain learns to distinguish previously undetectabl...
Deviance detection and regularity sensitivity in dissociated neuronal cultures [0.03%]
离体神经元培养中的偏差检测与规律敏感性
Zhuo Zhang,Amit Yaron,Dai Akita et al.
Zhuo Zhang et al.
Introduction: Understanding how neural networks process complex patterns of information is crucial for advancing both neuroscience and artificial intelligence. To investigate fundamental principles of neural computation, ...
Zhaofan Liu,CongCong Du,KongFatt Wong-Lin et al.
Zhaofan Liu et al.
Bow-tie architecture (BTA) is widely observed in biological neural systems, yet the underlying mechanism driving its spontaneous emergence remains unclear. In this study, we identify a novel formation mechanism by training multi-layer neura...
Volitional and forced running ability in mice lacking intact primary motor cortex [0.03%]
完整初级运动皮层缺失小鼠的意志跑步和被迫跑步能力
Ryusei Abo,Mei Ishikawa,Rio Shinohara et al.
Ryusei Abo et al.
The coordination of various brain regions achieves both volitional and forced motor control, but the role of the primary motor cortex in proficient running motor control remains unclear. This study trained mice to run at high performance (>...
Yuhao Sun,Wantong Liao,Jinhao Li et al.
Yuhao Sun et al.
Synaptic plasticity underlies adaptive learning in neural systems, offering a biologically plausible framework for reward-driven learning. However, a question remains: how can plasticity rules achieve robustness and effectiveness comparable...
Effective training procedure for a simultaneous bimanual movement task in head-fixed mice [0.03%]
头固定鼠同时进行双臂运动任务的有效训练程序
Kotaro Tezuka,Hironobu Osaki,Kaneyasu Nishimura et al.
Kotaro Tezuka et al.
Bimanual movements consist of simultaneous and nonsimultaneous movements. The neural mechanisms of unimanual and nonsimultaneous bimanual movements have been explored in rodent studies through electrophysiological recordings and calcium ima...
Differentiation between bipolar disorder and major depressive disorder based on AMPA receptor distribution [0.03%]
基于AMPA受体分布区分双相情感障碍和重大抑郁障碍
Sakiko Tsugawa,Yuichi Kimura,Junichi Chikazoe et al.
Sakiko Tsugawa et al.
An accurate diagnostic method using biological indicators is critically needed for bipolar disorder (BD) and major depressive disorder (MDD). The excitatory glutamate α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is...