Exosome-nanomaterial hybrid nanomedicine for ischemic stroke: microenvironment-informed design, therapeutic applications, and translational challenges [0.03%]
用于缺血性卒中的外泌体-纳米材料混合型纳米药物:微环境指导的设计、治疗应用和转化挑战
Qi Zhu,Xiaodan Wu
Qi Zhu
Ischemic stroke (IS) remains a major cause of mortality and long-term disability despite advances in reperfusion therapy, underscoring the need for adjunctive interventions that can operate within the dynamic post-ischemic microenvironment....
Nicotine combined with estrogen activates protein kinase PKCι and TAO, while inhibiting specific MAP kinase pathways in cultured human neurons: an atlas of kinase activities for nicotine use disorder [0.03%]
尼古丁与雌激素通过激活PKCι和TAO蛋白激酶,抑制特定的MAP激酶途径在培养的人体神经元中发挥作用:关于尼古丁使用障碍的激酶活动图集
Sally N Pauss,Zachary A Kipp,Genesee J Martinez et al.
Sally N Pauss et al.
Introduction: Women exhibit sex-specific differences in their responses to nicotine, with sex hormones like estrogen and progesterone playing key roles in nicotine addiction among women. Nicotine disrupts neuronal firing ...
Astrocyte heterogeneity and hierarchical information flow: reframing glial computation [0.03%]
astrocyte异质性和分级信息流:重塑胶质细胞计算
Oswaldo Pérez,James Schummers,Mónica López-Hidalgo
Oswaldo Pérez
Astrocytes are active elements in the brain; they exhibit complex, highly branched processes that contact neurons and blood vessels to regulate neuronal activity and vasoactive responses. Distal processes receive information that is integra...
Cognitive and neurodevelopmental outcomes in spinal muscular atrophy: a scoping review [0.03%]
脊髓性肌萎缩的认知和神经发育结局的纲要回顾
Martina Gnazzo,Giulia Pisanò,Valentina Baldini et al.
Martina Gnazzo et al.
Spinal muscular atrophy (SMA) has traditionally been described as a motor neuron disorder; however, increasing evidence suggests a broader neurodevelopmental involvement, particularly in the era of disease-modifying therapies. As survival a...
SMΝΔ7 mice show breathing and airflow defects with significant pathology of respiratory and oral tract tissues [0.03%]
SMNDelta7小鼠表现出呼吸和气流缺陷以及显著的呼吸道和口腔道组织病理学损伤
Roxanne Muchow,Michelle Woolridge,Catherine L Smith et al.
Roxanne Muchow et al.
Introduction: Spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by SMN1 mutations, leading to SMN protein deficiency and motor neuron loss. While progressive weakness, respiratory defects, and oral dysf...
Effects of volatile anesthetics on peripheral nerve regeneration in a sciatic cut repair murine model [0.03%]
吸入麻醉药对坐骨神经切断修复鼠模型外周神经再生的影响
Yameng Xu,Ying Yan,Wilson Z Ray et al.
Yameng Xu et al.
Background: We previously showed that 2% isoflurane conditioning promoted axonal and myelin regeneration leading to improved functional outcomes after peripheral nerve injury (PNI) in a sciatic nerve cut repair model. Whe...
Correction: Acetylcholine receptor stimulation activates protein kinase C mediated internalization of the dopamine transporter [0.03%]
订正:乙酰胆碱受体激活通过蛋白激酶C介导多巴胺转运体的内吞作用
Suzanne M Underhill,Susan G Amara
Suzanne M Underhill
[This corrects the article DOI: 10.3389/fncel.2021.662216.]. Keywords: dopamine transporter; internalization...
Published Erratum
Frontiers in cellular neuroscience. 2026 Jun 17:20:1864769. DOI:10.3389/fncel.2026.1864769 2026
Defining spinal motor neuron subtypes across development: from embryonic specification to postnatal maturation [0.03%]
脊髓运动神经元亚型的定义:从胚胎分化到出生后成熟
Olga Blauth,Urszula Sławińska,Małgorzata Zawadzka
Olga Blauth
Spinal motor neurons are essential for translating neural activity into coordinated muscle contraction, yet defining their functional subtypes across development remains a persistent challenge. While embryonic patterning establishes the ini...
Brief mechanical pulses induce sustained intracellular L-lactate production in astrocytes [0.03%]
短暂的机械脉冲诱导星形胶质细胞持续产生L-乳酸
Kaja Belko Parkel,Danaja Kuhanec,Živa Tajda Gržina et al.
Kaja Belko Parkel et al.
Intracranial-pressure transients impose mechanical strain on perivascular astrocytes, but it is unclear whether brief mechanical events elicit metabolic responses. Here, we applied 1.5-s pressure-driven mechanical stimuli (5-1,000 hPa) to c...
Effects of ethanol leaf extract of Spondias mombin on scopolamine-induced hippocampal neurodegeneration in adult male Wistar rats: evidence from behavioral, biochemical, histological, and immunohistochemical analyses [0.03%]
Spondias mombin乙醇叶提取物对Wistar大鼠烟碱诱导的海马神经退行性病变的影响:行为学、生化、组织病理和免疫组化分析证据
Temidayo Matthew Ale,Babatunde Elijah Arayombo,Alfred Wehdoe Sloh Jr
Temidayo Matthew Ale
Previous studies have demonstrated that phytochemicals present in Spondias mombin leaves possess neuro-regenerative and neuroprotective potentials. This study therefore evaluated the effects of ethanol leaf extract of Spondias mombin (ELESM...