Adolescent stress exposure: behavioral consequences and molecular mechanisms in corticolimbic networks [0.03%]
青春期应激暴露:皮质边缘系统的行为后果和分子机制研究
Evelin M Cotella,Rachel D Moloney,Parinaz Mahbod et al.
Evelin M Cotella et al.
Introduction: Adolescence is a sensitive developmental period during which chronic stress can induce lasting adaptations in corticolimbic circuits involved in stress regulation, cognition, and emotional behavior. We exami...
Mitochondrial dysfunction in intracerebral hemorrhage: molecular mechanisms and pathological consequences [0.03%]
脑内出血中的线粒体功能障碍:分子机制和病理后果
Tong Chen,Xu Gao,Yuhao Chang et al.
Tong Chen et al.
Intracerebral hemorrhage (ICH) carries high rates of disability and mortality, with a poor prognosis largely attributable to secondary brain injury (SBI). Mitochondria, a central hub for cellular redox regulation and energy metabolism, are ...
Characterization of TRPV2-associated pathology in Parkinson's disease and therapeutic modulation using Tranilast [0.03%]
TRPV2相关通路在帕金森病病理中的作用及使用Tranilast进行治疗干预的研究
Apeksha Chunchuwar,Bhupesh Vaidya,Shyam Sunder Sharma
Apeksha Chunchuwar
Introduction: Transient Receptor Potential (TRP) channels have gained worldwide attention for their expression and distribution in multiple human organs. Among these TRPs, Transient Receptor Potential Vanilloid (TRPV) cha...
The identification of white matter fibers in the hematoma of intracerebral hemorrhage patients [0.03%]
颅内出血患者脑血肿区内白质纤维束的识别
Jianan Wu,Cheng Zhang,Xian Yu et al.
Jianan Wu et al.
Background: Intracerebral hemorrhage (ICH) carries high mortality, and survivors often have severe neurological deficits. Although surgical clot evacuation is widely used, clinical trials have not demonstrated a clear ben...
Circadian rhythms of neuronal and astrocytic glutamate transporters in the suprachiasmatic nucleus of mice [0.03%]
小鼠视交叉上核神经元和星形胶质细胞谷氨酸转运体的昼夜节律性
Hussein Haidar,Amira A H Ali,Charlotte von Gall et al.
Hussein Haidar et al.
Retinal ganglion cells release glutamate at their synapses, transmitting visual signals via the optic nerve to brain regions involved in vision and light-dependent functions. Glutamatergic input to the circadian pacemaker, the suprachiasmat...
Loss of epigenetic adaptation to a high-fat diet in alpha-synuclein transgenic mice [0.03%]
高脂肪饮食表观遗传适应在α-突触核蛋白转基因小鼠中的丢失
Vivien Hoof,Samantha L Schaffner,Kristy Dever et al.
Vivien Hoof et al.
Introduction: In humans, a high-fat diet and obesity are associated with a higher risk and accelerated progression of Parkinson's disease (PD). Similarly, in animal models a high-fat diet exacerbates PD-related phenotypes...
Growth hormone restrains inflammatory activity of microglia/macrophages in CNS autoimmunity [0.03%]
生长激素通过限制CNS自身免疫性疾病中微胶质细胞/小胶质细胞的炎症活性来发挥免疫抑制作用
Anica Zivkovic,Milica Lazarević,Ivana Stevanovic et al.
Anica Zivkovic et al.
Growth hormone (GH) has been implicated in immune regulation, but its effects on microglia/macrophages during neuroinflammation remain insufficiently characterized. Here, we investigated the impact of GH on microglia/macrophages activation ...
Correction: Glutamate imaging reveals multiple sites of stochastic release in the CA3 giant mossy fiber boutons [0.03%]
纠正:谷氨酸成像揭示了CA3巨大型 mossy纤维boutons的多个随机释放位点
Sylvain Rama,Thomas P Jensen,Dmitri A Rusakov
Sylvain Rama
[This corrects the article DOI: 10.3389/fncel.2019.00243.]. Keywords: CA3 pyramidal cell; action potential; ...
Published Erratum
Frontiers in cellular neuroscience. 2026 Jul 30:20:1932278. DOI:10.3389/fncel.2026.1932278 2026
Neurogenesis defects in iPSC-derived midbrain organoids of early-onset Parkinson's disease with 22q11.2 deletion syndrome [0.03%]
22q11.2缺失综合征早发帕金森病 iPSC衍生中脑类器官神经发生缺陷
Syugo Ueki,Toshiya Kimura,Rie Tohge et al.
Syugo Ueki et al.
Sporadic Parkinson's disease (PD) is typically a late-onset disorder caused by a combination of genetics, environment, and aging, manifesting when the loss of midbrain dopaminergic neurons exceeds a critical threshold, usually after the age...
CD22 regulates Aβ clearance in microglia through INPP5D signaling [0.03%]
CD22通过INPP5D信号调节小胶质细胞中的Aβ清除作用
De-Zhi Zou,Jun Li,Qiu-Shuang Long et al.
De-Zhi Zou et al.
Introduction: Impaired microglial clearance of amyloid-β (Aβ) is a central driver of Alzheimer's disease (AD), yet the mechanisms governing intracellular Aβ degradation remain poorly defined. ...