Desensitization, trafficking, and resensitization of the pituitary thyrotropin-releasing hormone receptor [0.03%]
关于垂体促甲状腺激素释放因子受体脱敏、转运和再敏化的问题
Patricia M Hinkle,Austin U Gehret,Brian W Jones
Patricia M Hinkle
The pituitary receptor for thyrotropin-releasing hormone (TRH) is a calcium-mobilizing G protein-coupled receptor (GPCR) that signals through Gq/11, elevating calcium, and activating protein kinase C. TRH receptor signaling is quickly desen...
Systematic Error in Hippocampal Volume Asymmetry Measurement is Minimal with a Manual Segmentation Protocol [0.03%]
手动分割协议下海马体积不对称性测量的系统误差较小
Baxter P Rogers,Julia M Sheffield,Andrew S Luksik et al.
Baxter P Rogers et al.
Hemispheric asymmetry of hippocampal volume is a common finding that has biological relevance, including associations with dementia and cognitive performance. However, a recent study has reported the possibility of systematic error in measu...
Measuring abnormal brains: building normative rules in neuroimaging using one-class support vector machines [0.03%]
异常脑的测量：使用一类支持向量机建立神经影像的正常规则
João Ricardo Sato,Jane Maryam Rondina,Janaina Mourão-Miranda
João Ricardo Sato
Pattern recognition methods have demonstrated to be suitable analyses tools to handle the high dimensionality of neuroimaging data. However, most studies combining neuroimaging with pattern recognition methods focus on two-class classificat...
Eleftherios Garyfallidis,Matthew Brett,Marta Morgado Correia et al.
Eleftherios Garyfallidis et al.
Diffusion MR data sets produce large numbers of streamlines which are hard to visualize, interact with, and interpret in a clinically acceptable time scale, despite numerous proposed approaches. As a solution we present a simple, compact, t...
The little molecules that could: a story about microRNAs in neural stem cells and neurogenesis [0.03%]
可能的小分子：关于神经干细胞和神经发生中的微小RNA的故事
Grace E Asuelime,Yanhong Shi
Grace E Asuelime
Elevated Salivary Levels of Oxytocin Persist More than 7 h after Intranasal Administration [0.03%]
鼻内给予催产素后唾液中高水平的催产素可维持超过7小时
Marinus H van Ijzendoorn,Ritu Bhandari,Rixt van der Veen et al.
Marinus H van Ijzendoorn et al.
We addressed the question how long salivary oxytocin levels remain elevated after intranasal administration, and whether it makes a difference when 16 or 24 IU of oxytocin administration is used. Oxytocin levels were measured in saliva samp...
101 labeled brain images and a consistent human cortical labeling protocol [0.03%]
101张标记好的脑图象以及一致的皮层标注方案
Arno Klein,Jason Tourville
Arno Klein
We introduce the Mindboggle-101 dataset, the largest and most complete set of free, publicly accessible, manually labeled human brain images. To manually label the macroscopic anatomy in magnetic resonance images of 101 healthy participants...
Claudia E Feierstein
Claudia E Feierstein
IN THE ADULT BRAIN, NEW NEURONS ARE ADDED TO TWO BRAIN AREAS: the olfactory bulb (OB) and the hippocampus. Newly-generated neurons integrate into the preexisting circuits, bringing a set of unique properties, such as increased plasticity an...
Robust Automated Amygdala Segmentation via Multi-Atlas Diffeomorphic Registration [0.03%]
基于多图谱微分同胚配准的鲁棒杏仁核自动分割方法
Jamie L Hanson,Jung W Suh,Brendon M Nacewicz et al.
Jamie L Hanson et al.
Here, we describe a novel method for volumetric segmentation of the amygdala from MRI images collected from 35 human subjects. This approach is adapted from open-source techniques employed previously with the hippocampus (Suh et al., 2011; ...
Complexity and competition in appetitive and aversive neural circuits [0.03%]
appetitive和aversive神经环路的复杂性和竞争性
Crista L Barberini,Sara E Morrison,Alex Saez et al.
Crista L Barberini et al.
Decision-making often involves using sensory cues to predict possible rewarding or punishing reinforcement outcomes before selecting a course of action. Recent work has revealed complexity in how the brain learns to predict rewards and puni...