Tonsillectomy with steroid pulse: a curative therapy for IgA nephropathy [0.03%]
扁桃体切除联合激素冲击治疗IgA肾病的疗效观察
Osamu Hotta
Osamu Hotta
IgA nephropathy (IgAN), the most common form of primary glomerulonephritis progressing to end-stage renal disease (ESRD), has been regarded as an incurable disease. However, in recent years, it has been demonstrated that combined tonsillect...
Craniofacial mucosal immune system: importance of its unique organogenesis and function in the development of a mucosal vaccine [0.03%]
颅面黏膜免疫系统：其独特的器官发生及功能在黏膜疫苗开发中的重要性
Kazunari Okada,Tatsuya Yamasoba,Hiroshi Kiyono
Kazunari Okada
Mucosa-associated lymphoid tissues (MALT) play a critical role as inductive sites for the initiation of antigen-specific protective immunity against pathogens penetrating the mucus membranes. Nasopharynx-associated lymphoid tissue (NALT), s...
Mucosal immune barrier and antigen-presenting system in human nasal epithelial cells [0.03%]
人鼻上皮细胞的黏膜免疫屏障和抗原呈递系统
Tetsuo Himi,Ken-ichi Takano,Noriko Ogasawara et al.
Tetsuo Himi et al.
The upper respiratory tract including the nasal cavity, which is the first site of invading antigen exposure, plays a crucial role in host defense via the mucosal immune response. The epithelium of nasal mucosa forms a continuous barrier ag...
David E Briles,Eliane Miyaji,Yoshiko Fukuyama et al.
David E Briles et al.
Pneumococcal diseases such as otitis media, pneumonia, and meningitis are invariably preceded by nasopharyngeal colonization, and herd immunity against pneumococcal disease requires protection against colonization. An early study in mice de...
Per Brandtzaeg
Per Brandtzaeg
This brief review will focus on nasopharynx-associated lymphoid tissue as a unique inductive immune site for B cell responses and plasma cell generation. The anatomical and immunological characteristics of Waldeyer's lymphoid ring should ma...
Noboru Yamanaka
Noboru Yamanaka
The palatine and nasopharyngeal tonsils (adenoids) are lymphoepithelial tissues located in strategic anatomical areas of the oral pharynx and nasopharynx. These immunocompetent tissues represent the first line of defense against ingested or...
Clinical manifestations and pathogenesis of tonsillar focal diseases: IgA nephropathy and palmoplantar pustulosis [0.03%]
扁桃体局灶性疾病的表现与发病机理：IgA肾病和掌跖脓疱病
Yasuaki Harabuchi
Yasuaki Harabuchi
Tonsillar focal disease is defined as clinical disorders in the distant organ from the tonsil that are caused by the tonsils without any symptoms of the tonsil itself. Palmoplantar pustulosis and IgA nephropathy are known typical tonsillar ...