Anna M Imiela,Tomasz P Mikołajczyk,Tomasz J Guzik et al.
Anna M Imiela et al.
Venous thromboembolism, encompassing acute pulmonary embolism (APE) and deep vein thrombosis (DVT), is a potentially fatal disease with complex pathophysiology. Traditionally, the Virchow triad provided a framework for understanding the pat...
Human Soluble TRAIL Secreted by Modified Lactococcus lactis Bacteria Promotes Tumor Growth in the Orthotopic Mouse Model of Colorectal Cancer [0.03%]
人可溶性TRAIL通过修饰的乳酸乳球菌细菌在结肠癌小鼠模型中促进肿瘤生长
Katarzyna Kaczmarek,Jerzy Więckiewicz,Ivo Que et al.
Katarzyna Kaczmarek et al.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis of sensitive cancer cells, including colorectal cancer (CRC). Due to its short biological half-life after intravenous administration and related c...
Karol Gostomczyk,Jędrzej Borowczak,Marta Siekielska-Domanowska et al.
Karol Gostomczyk et al.
The widespread occurrence of SARS-CoV-2 infections and the diverse range of symptoms have placed significant strain on healthcare systems worldwide. Pregnancy has also been affected by COVID-19, with an increased risk of complications and u...
Assessment of Motor Unit Potentials Duration as the Biomarker of DT-DEC01 Cell Therapy Efficacy in Duchenne Muscular Dystrophy Patients up to 12 Months After Systemic-Intraosseous Administration [0.03%]
评估DT-DEC01细胞治疗在系统性-骨内给药后长达12个月内对杜氏肌营养不良患者运动单元电位持续时间疗效的生物标志物评估
Adam Niezgoda,Grzegorz Biegański,Jacek Wachowiak et al.
Adam Niezgoda et al.
Duchenne muscular dystrophy (DMD) is a lethal X-linked disease caused by mutations in the dystrophin gene, leading to muscle degeneration and wasting. Electromyography (EMG) is an objective electrophysiological biomarker of muscle fiber fun...
Expression of Angiopoietin-2 in Lung Tissue of Juvenile SD Rats with Lipopolysaccharide-Induced Acute Lung Injury and the Role of Ulinastatin [0.03%]
乌司他丁对脂多糖诱导的大鼠急性肺损伤肺组织中Angiopoietin-2表达的影响
Junying Qiao,Shanshan Guo,Xianjie Huang et al.
Junying Qiao et al.
This study aimed to observe the expression of angiopoietin-2 (Ang-2) in the lung tissue of juvenile SD rats with lipopolysaccharide (LPS)-induced acute lung injury (ALI) and to clarify the role of ulinastatin (UTI). Ninety 18-21-day-old juv...
Correction to: In Situ Programming of CAR-T Cells: A Pressing Need in Modern Immunotherapy [0.03%]
correction to：“在体CAR-T细胞编程在现代免疫治疗中迫在眉睫”
Marta Śledź,Alicja Wojciechowska,Radosław Zagożdżon et al.
Marta Śledź et al.
Prolonged Exposure to High Glucose Induces Premature Senescence Through Oxidative Stress and Autophagy in Retinal Pigment Epithelial Cells [0.03%]
高糖诱导的氧化应激和自噬介导的人视网膜色素上皮细胞衰老
Chien-Chih Chiu,Kai-Chun Cheng,Yi-Hsiung Lin et al.
Chien-Chih Chiu et al.
Chronic hyperglycemia involves persistent high-glucose exposure and correlates with retinal degeneration. It causes various diseases, including diabetic retinopathy (DR), a major cause of adult vision loss. Most in vitro studies have invest...
Improved Production of Anti-FGF-2 Nanobody Using Pichia pastoris and Its Effect on Antiproliferation of Keratinocytes and Alleviation of Psoriasis [0.03%]
毕赤酵母高效表达抗FGF-2纳米抗体及其对抑制角质形成细胞增殖和治疗银屑病的影响
Zhenlong Zhou,Baixin Liao,Shengli Wang et al.
Zhenlong Zhou et al.
Fibroblast growth factor 2 (FGF-2) is not only an angiogenic factor, but also a mitogen for epidermal keratinocytes. FGF-2 has been shown to be positively immunoreactive in the basal layer of psoriatic lesions. In previous work, we used the...
Updated Clinical Perspectives and Challenges of Chimeric Antigen Receptor-T Cell Therapy in Colorectal Cancer and Invasive Breast Cancer [0.03%]
CAR-T细胞治疗结直肠癌和三阴性乳腺癌的临床进展与挑战
Yu Cao,Sergey K Efetov,Mingze He et al.
Yu Cao et al.
In recent years, the incidence of colorectal cancer (CRC) and breast cancer (BC) has increased worldwide and caused a higher mortality rate due to the lack of selective anti-tumor therapies. Current chemotherapies and surgical interventions...
In Situ Programming of CAR-T Cells: A Pressing Need in Modern Immunotherapy [0.03%]
CAR-T细胞的原位编程：现代免疫治疗亟待解决的问题
Marta Śledź,Alicja Wojciechowska,Radosław Zagożdżon et al.
Marta Śledź et al.
Chimeric antigen receptor-T (CAR-T) cell-based therapy has become a successful option for treatment of numerous hematological malignancies, but also raises hope in a range of non-malignant diseases. However, in a traditional approach, gener...