The Pathogenesis of Foot-and-Mouth Disease Virus Infection: How the Virus Escapes from Immune Recognition and Elimination [0.03%]
口蹄疫病毒的致病机理：病毒如何逃逸免疫识别与清除
Abdul Kabir,Kalim Ullah,Asghar Ali Kamboh et al.
Abdul Kabir et al.
Foot-and-mouth disease virus (FMDV) is a highly contagious and economically devastating pathogen that affects cloven-hoofed animals worldwide. FMDV infection causes vesicular lesions in the mouth, feet, and mammary glands, as well as severe...
Abnormalities of Coagulation and Fibrinolysis Assessed by Thromboelastometry in an Endotoxic Shock Model in Piglets Treated with Nitric Oxide and Hydrocortisone [0.03%]
血栓弹力图在内毒素性休克仔猪模型中一氧化氮和氢化可的松治疗凝血与纤溶异常中的应用评估研究
Barbara Adamik,Claes Frostell,Barbara Dragan et al.
Barbara Adamik et al.
This is an animal model study to investigate changes in hemostasis during endotoxemic shock and to determine whether the combination of inhaled nitric oxide (iNO) + intravenous hydrocortisone had an effect on clot formation and fibrinolysis...
MICB Genetic Variants and Its Protein Soluble Level Are Associated with the Risk of Chronic GvHD and CMV Infection after Allogeneic HSCT [0.03%]
MICB基因变异及其蛋白溶性水平与异基因造血干细胞移植后慢性GVHD和CMV感染的风险相关
Jagoda Siemaszko,Marta Dratwa,Agnieszka Szeremet et al.
Jagoda Siemaszko et al.
The aim of the present study was to determine the associations between the MICB genetic variability and the expression and the risk of development of post-transplant complications after allogeneic hematopoietic stem cell transplantation (HS...
Transplantation of Donor-Recipient Chimeric Cells Restores Peripheral Blood Cell Populations and Increases Survival after Total Body Irradiation-Induced Injury in a Rat Experimental Model [0.03%]
异基因供受体嵌合细胞移植可促进全身照射损伤小鼠外周血细胞恢复并提高其生存率
Maria Siemionow,Małgorzata Cyran,Katarzyna Stawarz et al.
Maria Siemionow et al.
Current therapies for acute radiation syndrome (ARS) involve bone marrow transplantation (BMT), leading to graft-versus-host disease (GvHD). To address this challenge, we have developed a novel donor-recipient chimeric cell (DRCC) therapy t...
Dendritic Cells and the Establishment of Fetomaternal Tolerance for Successful Human Pregnancy [0.03%]
树突状细胞与妊娠免疫耐受的建立
Deviyani Mahajan,Tarun Kumar,Prasana Kumar Rath et al.
Deviyani Mahajan et al.
Pregnancy is a remarkable event where the semi-allogeneic fetus develops in the mother's uterus, despite genetic and immunological differences. The antigen handling and processing at the maternal-fetal interface during pregnancy appear to b...
The Antigen-Processing Pathway via Major Histocompatibility Complex I as a New Perspective in the Diagnosis and Treatment of Endometriosis [0.03%]
主要组织相容性复合物I介导的抗原加工途径作为诊断和治疗子宫内膜异位症的新视角
Izabela Nowak,Patrycja Bochen
Izabela Nowak
Endometriosis is a debilitating gynecological disease defined as the presence of endometrium-like epithelium and/or stroma outside the uterine cavity. The most commonly affected sites are the pelvic peritoneum, ovaries, uterosacral ligament...
In Vitro Effects of Silver Nanoparticles on Pathogenic Bacteria and on Metabolic Activity and Viability of Human Mesenchymal Stem Cells [0.03%]
银纳米粒子对病原菌及人源间充质干细胞代谢活性和存活率的体外影响研究
Maja Ptasiewicz,Renata Chałas,Joanna Idaszek et al.
Maja Ptasiewicz et al.
The rapid development of nanotechnology has led to the use of silver nanoparticles (Ag-NPs) in various biomedical fields. However, the effect of Ag-NPs on human mesenchymal stem cells (hMSCs) is not fully understood. Moreover, too frequent ...
Artificial Intelligence, Big Data, and Regulation of Immunity: Challenges and Opportunities [0.03%]
人工智能，大数据与免疫调节：挑战与机遇
Bhagirath Singh,Anthony M Jevnikar,Eric Desjardins
Bhagirath Singh
The immune system is regulated by a complex set of genetic, molecular, and cellular interactions. Rapid advances in the study of immunity and its network of interactions have been boosted by a spectrum of "omics" technologies that have gene...
Insights into Autophagic Machinery and Lysosomal Function in Cells Involved in the Psoriatic Immune-Mediated Inflammatory Cascade [0.03%]
涉及银屑病免疫介导的炎症级联反应的细胞中自噬 machinery 和溶酶体功能的见解
Martyna Kuczyńska,Marta Moskot,Magdalena Gabig-Cimińska
Martyna Kuczyńska
Impaired autophagy, due to the dysfunction of lysosomal organelles, contributes to maladaptive responses by pathways central to the immune system. Deciphering the immune-inflammatory ecosystem is essential, but remains a major challenge in ...
Potential Gastric Cancer Immunotherapy: Stimulating the Immune System with Helicobacter pylori pIRES2-DsRed-Express- ureF DNA Vaccines [0.03%]
胃癌潜在免疫疗法：用幽门螺旋杆菌pIRES2-DsRed-ureF表达载体疫苗刺激免疫系统
Mahsa Afkhamipour,Fatemeh Kaviani,Samaneh Dalali et al.
Mahsa Afkhamipour et al.
Most gastric cancers (GC) are thought to be caused by Helicobacter pylori (H. pylori) infections. However, there is mounting evidence that GC patients with positive H. pylori status have improved prognoses. The H. pylori-induced cellular im...