Polymorphic Variants in the Vitamin D Receptor and Clinical Parameters of Rheumatoid Arthritis Patients Undergoing Anti-TNF Treatment [0.03%]
维生素D受体多态变异与抗TNF治疗类风湿性关节炎临床参数的相关性研究
Joanna Wielińska,Katarzyna Górna,Jerzy Świerkot et al.
Joanna Wielińska et al.
Vitamin D levels have been related to the severity and progression of various autoimmune disorders. In this study, we aimed to investigate the impact of genetic variability in the vitamin D receptor (VDR) gene on disease susceptibility and ...
S-Adenosylmethionine Treatment Diminishes the Proliferation of Castration-Resistant Prostate Cancer Cells by Modulating the Expression of miRNAs [0.03%]
S-腺苷甲硫氨酸通过调节微小RNA的表达减少雄激素非依赖性前列腺癌细胞增殖
Thomas Schmidt
Thomas Schmidt
AdoMet (S-adenosylmethionine) inhibits cancer cell proliferation and migration via epigenetic alterations. This study aimed to investigate whether AdoMet may cause alterations in microRNA (miRNA) expression profiles that are important for t...
Novel Insight into Inflammatory Pathways in Acute Pulmonary Embolism in Humans [0.03%]
人类急性肺栓塞中炎症途径的新见解
Anna M Imiela,Tomasz P Mikołajczyk,Piotr Pruszczyk
Anna M Imiela
Accumulating data have shown a pathophysiological association between inflammatory pathways and thrombosis. Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and acute pulmonary embolism (APE), is a significant health ...
S-Adenosylmethionine Inhibits the Proliferation of Retinoblastoma Cell Y79, Induces Apoptosis and Cell Cycle Arrest of Y79 Cells by Inhibiting the Wnt2/β-Catenin Pathway [0.03%]
S腺苷蛋氨酸通过抑制Wnt2/β-catenin信号通路诱导Y79细胞凋亡及周期阻滞从而抑制视网膜母细胞瘤细胞Y79增殖
Mushi Liu,Youchaou Mobet,Hong Shen
Mushi Liu
Retinoblastoma is one of the most common primary intraocular malignancies in young children. Traditional treatment methods such as chemotherapy often come with significant adverse effects, such as hearing loss, cognitive impairment, and vis...
Apoptosis Regulation in Dental Pulp Cells and PD-1/PD-L1 Expression Dynamics Under Ozone Exposure - A Pilot Approach [0.03%]
牙髓细胞凋亡调控及臭氧暴露下PD-1/PD-L1表达变化的探索性研究
Maja Ptasiewicz,Mirosław Orłowski,Agnieszka Magryś et al.
Maja Ptasiewicz et al.
This study aimed to determine the effect of ozone on the expression of Bax and Bcl-2 genes in dental pulp cells. Additionally, the programmed cell death protein 1, programmed death-ligand 1, and CD200 antigens were determined in lymphocytes...
Endothelial Activation and Stress Index Score as a Prognostic Factor of Cytokine Release Syndrome in CAR-T Patients - A Retrospective Analysis of Multiple Myeloma and Large B-Cell Lymphoma Cohorts [0.03%]
CAR-T细胞治疗患者细胞因子释放综合征的预后因素：多发性骨髓瘤和大B细胞淋巴瘤队列的回顾性分析
Jaromir Tomasik,Batia Avni,Sigal Grisariu et al.
Jaromir Tomasik et al.
Endothelial Activation and Stress Index (EASIX) has been proposed as a prognostic factor of adverse events or survival in hematological malignancies. Endothelial dysfunction has been associated with complications following stem cell transpl...
Maciej Szymczak,Harald Heidecke,Marcelina Żabińska et al.
Maciej Szymczak et al.
We evaluated the concentration of AT2R antibodies in 136 patients with primary and secondary glomerular diseases: membranous nephropathy (n = 18), focal and segmental glomerulosclerosis (n = 25), systemic lupus erythematosus (n = 17), immun...
The Healthcare Study Examines the Humoral Anti-S1 Antibody Response Following mRNA Vaccination, Comparing Individuals with and without Prior SARS-CoV-2 Infection [0.03%]
关于mRNA疫苗接种后有和没有既往新冠病毒感染个体的S1抗体反应的研究
Małgorzata Staruszkiewicz,Anna Pituch-Noworolska,Mohamad Skayne et al.
Małgorzata Staruszkiewicz et al.
Vaccines targeting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been pivotal in curtailing the spread of infection. Health care workers, as frontline responders, were among the first to receive vaccination to mitigate c...
Michal Olejarz,Ewelina Szczepanek-Parulska,Aleksandra Krygier et al.
Michal Olejarz et al.
Elevated immunoglobulin G4 (IgG4) serum antibodies are an important feature of IgG4-related disease. However, IgG4 antibodies can play a role in autoimmune thyroid disorders. In this study, we aimed to evaluate the impact of serum IgG4 leve...
Solute Carrier Transporters in Synovial Membrane and Hoffa's Pad of Patients with Rheumatoid Arthritis [0.03%]
类风湿关节炎患者滑膜及霍夫帕垫溶质载体转运体的表达特征分析
Damian Malinowski,Katarzyna Piotrowska,Marek Droździk et al.
Damian Malinowski et al.
Rheumatoid arthritis (RA) is a complex autoimmune disease that leads to joint destruction. A number of immune cells that affect joint tissues are involved in the pathogenesis of this disease. This leads to the synthesis of many pro-inflamma...