Marta E Alarcón-Riquelme
Marta E Alarcón-Riquelme
The present review is aimed at describing the main works that have used gene expression to analyze tissue kidney samples of lupus nephritis patients. Most studies used the gene expression arrays, which enormously advanced our knowledge on t...
Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study [0.03%]
羟氯喹治疗对免疫球蛋白亚类缺乏及系统性红斑狼疮、舍格伦综合征和类风湿关节炎女性患者血清免疫球蛋白水平的影响：一项回顾性研究
James C Barton,J Clayborn Barton,Luigi F Bertoli
James C Barton
Hydroxychloroquine (HCQ) therapy decreased immunoglobulin (Ig) levels in patients with Sjögren syndrome (SS) and rheumatoid arthritis (RA) in previous studies. We found no report of Ig levels of women with IgG subclass deficiency (IgGSD) a...
Preliminary Results for Personalized Therapy in Pregnant Women with Polycystic Ovary Syndrome During the COVID-19 Pandemic [0.03%]
新冠疫情期间多囊卵巢综合征孕产妇的个性化治疗初步结果
Małgorzata Jerzak,Monika Szafarowska
Małgorzata Jerzak
Increased androgen level, hyperinsulinemia, diabetes, impaired fibrinolysis, obesity, hypertension, chronic inflammation, abnormal immune response to infections and hyperhomocysteinemia are the most common abnormalities related to polycysti...
Study of Plasma Anti-CD26 Autoantibody Levels in a Cohort of Treatment-Naïve Early Arthritis Patients [0.03%]
未治疗的早期关节炎患者血浆抗CD26自身抗体水平的研究
Oscar J Cordero,Irene Viéitez,Irene Altabás et al.
Oscar J Cordero et al.
In rheumatoid arthritis (RA), the identification of biomarkers to adjust treatment intensity and to correctly diagnose the disease in early stages still constitutes a challenge and, as such, novel biomarkers are needed. We proposed that aut...
Pauline M Montigny,Frédéric A Houssiau
Pauline M Montigny
The aim of this study is to report major recent progresses in the treatment of lupus nephritis (LN). Results of controlled randomized trials are discussed in view of the unmet needs in the field. Current treatments of LN are not satisfactor...
CD5L Secreted by Macrophage on Atherosclerosis Progression Based on Lipid Metabolism Induced Inflammatory Damage [0.03%]
基于脂质代谢诱导的炎症损伤的巨噬细胞分泌的CD5L在动脉粥样硬化进展中的作用机制研究
Liang Wang,Lijuan Liu,Wei Qian et al.
Liang Wang et al.
To explore the molecular mechanism of exosomal protein CD5L secreted by macrophage to promote the progression of atherosclerosis. Twenty cases of patients with atherosclerosis (AS) and 20 cases of healthy subjects were collected. Morphologi...
Recombinant Human Lactoferrin Reduces Inflammation and Increases Fluoroquinolone Penetration to Primary Granulomas During Mycobacterial Infection of C57Bl/6 Mice [0.03%]
重组人乳铁蛋白可减少炎症并增加氟喹诺酮类药物在小鼠结核菌感染初期病灶中的穿透性
Thao K T Nguyen,Zainab Niaz,Marian L Kruzel et al.
Thao K T Nguyen et al.
Infection with Mycobacterium tuberculosis (Mtb) results in the primary formation of a densely packed inflammatory foci that limits entry of therapeutic agents into pulmonary sites where organisms reside. No current therapeutic regimens exis...
Treat-to-Target in Lupus Nephritis. What is the Role of the Repeat Kidney Biopsy? [0.03%]
狼疮性肾炎治疗目标中的重复肾脏活检的作用是什么？
Ioannis Parodis,Farah Tamirou,Frédéric A Houssiau
Ioannis Parodis
Kidney involvement, termed lupus nephritis (LN), develops in 35-60% of patients with systemic lupus erythematosus, often early during the disease course. When not treated promptly and efficiently, LN may lead to rapid and severe loss of kid...
Marta Grochowska,Karol Perlejewski,Tomasz Laskus et al.
Marta Grochowska et al.
Disturbances in gastrointestinal (GI) microbiota could play a significant role in the development of GI cancers, but the underlying mechanisms remain largely unclear. While some bacteria seem to facilitate carcinogenesis, others appear to b...
Effects of Local Nasal Immunotherapy with FIP-fve Peptide and Denatured Tyrophagus putrescentiae for Storage Mite-Induced Airway Inflammation [0.03%]
地化泰罗菲博氏螨和FIP-fve肽局部鼻免疫治疗对储藏螨诱发的变应性气道炎症的影响
Chung-Yang Yen,Ching-Hsiang Yu,Jaw-Ji Tsai et al.
Chung-Yang Yen et al.
Allergic diseases are affecting public health and have increased over the last decade. Sensitization to mite allergens is a considerable trigger for allergy development. Storage mite-Tyrophagus putrescentiae shows great significance of alle...