The Epidermal Environment's Influence on the Dermal Environment in Response to External Stress [0.03%]
表皮环境对皮肤屏障外部压力响应的影响研究进展
Masaki Yoshida,Kyong-Oh Shin,Sora Muraoka et al.
Masaki Yoshida et al.
Introduction: The outermost layer of the skin, the epidermis, is directly exposed to external stress (e.g., irradiation, allergens, and chemicals). Changes in epidermal conditions/environment in response to this stress co...
Bin Wang,You-Dong Li,Zi-Yan Wang et al.
Bin Wang et al.
Autism is a neurodevelopmental disorder. Individuals with autism can exhibit multiple neurological symptoms such as deficit in social communication, restricted interests, and repetitive behaviors. Recent study showed that murine model of au...
Development of an in vitro Functional Assay to Evaluate the Occlusive Properties of Moisturizers on Dry Skin [0.03%]
体外保湿剂封闭性能评价方法的建立及应用研究干燥皮肤屏障修复能力
Soonjin Hong,Prithwiraj Maitra,Audrey Nguyen et al.
Soonjin Hong et al.
Introduction: Dry skin is a hallmark of impaired skin barrier function. Moisturizers are a mainstay of treatment to help the skin retain moisture, and there is a high consumer demand for effective products. However, the d...
Evaluation of a Novel Skin Emollient Cream on Skin Lipidome and Lipid Organization [0.03%]
一种新型皮肤润肤霜对皮肤脂质组和脂质组织的影响评估研究
Carine Jacques,Caroline Dejean,Christian Klose et al.
Carine Jacques et al.
Introduction: The stratum corneum (SC) matrix is composed of free fatty acids, cholesterol, and ceramides (CERs), which play a key role in the skin barrier function. Changes in the composition and content of skin lipids w...
Doris Wilborn,Ruhul Amin,Jan Kottner et al.
Doris Wilborn et al.
Background: Skin care is a basic, daily activity performed by formal and informal caregivers from birth until end of life. Skin care activities are influenced by different factors, e.g., culture, knowledge, industrial dev...
MAPK/AP-1 Signaling Pathway Is Involved in the Protection Mechanism of Bone Marrow Mesenchymal Stem Cells-Derived Exosomes against Ultraviolet-Induced Photoaging in Human Dermal Fibroblasts [0.03%]
骨髓间充质干细胞衍生的外泌体通过MAPK/AP-1信号途径机制对抗紫外线诱导的人成纤维细胞光老化损伤
Tingting Yan,Lining Huang,Yunling Yan et al.
Tingting Yan et al.
Introduction: The role of bone marrow mesenchymal stem cells-derived exosomes (BMSCs-exo) in skin photoaging was explored in human dermal fibroblasts (HDFs). The underlying mechanism was further explored. ...
Permethrin Steal Effect by Unmasked Corneocytic Keratin in Topical Therapy of Scabies [0.03%]
外用治疗疥疮时氯氰菊酯对未被掩盖角质蛋白的窃取效应
Luisa Scholz,Claudia Fritz,Julia Chuttke et al.
Luisa Scholz et al.
Introduction: The use of epicutaneously applied permethrin in the treatment of common scabies is considered to be the first-line therapy. Due to increasing clinical treatment failure, the development of genetic resistance...
Application of Topical Sandalore® Increases Epidermal Dermcidin Synthesis in Organ-Cultured Human Skin ex vivo [0.03%]
体外人皮肤器官培养中局部应用沙尔多宁®可增加表皮dermcidin合成
Janin Edelkamp,Marta B Lousada,Daniela Pinto et al.
Janin Edelkamp et al.
Introduction: Several olfactory receptors (ORs) are expressed in human skin, where they regulate skin pigmentation, barrier function, wound healing, and hair growth. Previously, we found that the selective activation of O...
Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice [0.03%]
微损伤引起的肿瘤坏死因子-α激增刺激小鼠毛发生长
Guang-Ri Jin,Su Bin Hwang,Hyeon Ju Park et al.
Guang-Ri Jin et al.
Introduction: Tumor necrosis factor (TNF)-α released after follicular injury such as that caused by plucking plays a role in the activation of hair regeneration. Microneedle (MN) treatment is applied to the scalp to incr...
Histamine Skin Prick Tests: From Established Diagnostic Technique to Advanced Experimental Biomarker [0.03%]
组胺皮试刺测验：从成熟的诊断技术到先进的实验生物标志物
Dorien Bamps,Katarina Berdon,Hasan Hernandez et al.
Dorien Bamps et al.
Introduction: Skin prick tests have a long history as diagnostic and pharmacodynamic biomarker. Besides visual assessments of the wheal and flare, objective blood flow measurements using laser Doppler imaging (LDI) and la...