Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity [0.03%]
用局部用药的 timolol 治疗糖尿病足部溃疡可改善愈合上皮的完整性
Rawlings E Lyle,Mirabel E Dafinone,Pallas Lim et al.
Rawlings E Lyle et al.
Introduction: Diabetic foot ulcers are a common complication in diabetes, leading to high amputation risk and significant healthcare costs. Given topical timolol's emergence as a potential wound-healing agent, our study e...
Emulsifier-induced changes to the human skin barrier - Connection to ceramide profiles and assessment as a skin lesion model [0.03%]
乳化剂诱导的人体皮肤屏障变化——与神经酰胺谱的关联及其作为皮肤损伤模型的评估
Moritz Reuter,Hans Schoenfelder,Annette Gaiser et al.
Moritz Reuter et al.
Emulsifiers are common excipients in dermal products stabilizing formulations such as creams and emulsions. But due to their potential for skin irritation, emulsifiers for pharmaceutical use should be tested regarding their tolerability bef...
Effects of two different basic skin care regimens on children and adult skin microbiota: an exploratory randomized controlled crossover trial [0.03%]
两种不同基础皮肤护理程序对儿童和成人皮肤微生物群的影响：一项探索性的随机对照交叉试验
Kathrin Hillmann,Tsenka Tomova-Simitchieva,Pauline Sophia Pinta et al.
Kathrin Hillmann et al.
Regular use of leave-on skin care products has positive effects on the skin barrier and appears to influence the skin microbiome in atopic dermatitis (AD). However, product-related effects on the skin microbiome are unclear. The aim of this...
Intake of soymilk-okara powder for 8 weeks induced the improvement of skin elasticity in Japanese women [0.03%]
大豆豆渣粉的8周摄取可改善日本女性皮肤弹性
Akihiro Maeta,Masahiro Katsukawa,Yaeko Hayase et al.
Akihiro Maeta et al.
Introduction: Soymilk-okara, a rich source of protein and dietary fiber, is a byproduct of soymilk manufacturing. We investigated whether soymilk okara intake improved skin conditions in Japanese women with self-reported ...
Skin transcriptomic analysis reveals altered fatty acid metabolism pathways in mice subjected to sleep fragmentation [0.03%]
皮肤转录组学分析揭示了睡眠片段化小鼠脂肪酸代谢途径的改变
Da-Been Lee,Seung-Lim Yoo,June Seok Heo et al.
Da-Been Lee et al.
Introduction Sleep fragmentation (SF) is a hallmark of sleep disorders and has been associated with systemic health issues, but its specific impact on skin health remains unclear. This study aimed to investigate whether SF impairs skin barr...
MiR-211 regulates cutaneous wound healing through inhibiting inflammatory reactions and oxidative stress by binding SOX11 [0.03%]
microRNA-211通过结合SOX11抑制炎症反应和氧化应激从而促进皮肤伤口愈合
Yun Chen,Xinyi Zhang,Fangfang Wu et al.
Yun Chen et al.
Introduction: Loss of skin integrity due to a wound or disease can lead to severe disability or even life threat. The highly expressed microRNAs in the skin are of great significance for skin development. The investigatio...
How to Choose an Emollient? Pharmaceutical and sensory attributes for product selection [0.03%]
如何选择皮肤保湿剂？基于药理及感官属性的产品选择指南
Petra Huber,Daphne Reinau,Zoé Brodard et al.
Petra Huber et al.
Introduction: Emollients are part of daily body care and have become indispensable therapeutic adjuvants for the treatment of dry skin conditions. Adherence to topical treatments, notably for dry skin conditions, has been...
In vitro antibacterial and antifungal activity of a skin ointment and its active pharmaceutical ingredients larch turpentine, turpentine oil, and eucalyptus oil [0.03%]
含杜松乳香脂、松节油及尤加利油皮肤软膏的体外抗菌抗霉活性及其有效药物成分的体外抗菌抗真菌活性研究
Elisa Zimmermann,Nils Günnewich,Christian Zimmermann et al.
Elisa Zimmermann et al.
Introduction: Turpentine derivatives and Eucalyptus oil are herbal substances traditionally used to treat various skin infections. Limited non-clinical data suggest they exert an immunological activity, but only scant inf...
The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis [0.03%]
反应性氧物质在斑秃发病机制中的作用：系统回顾和荟萃分析
Jonah Perlmutter,Polycronis P Akouris,Sierra Fremont et al.
Jonah Perlmutter et al.
Background: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that significantly impacts patient quality of life. The breakdown of hair follicle immune privilege underlies AA pathogenesis. However, the precise ...
In vivo study to evaluate an intelligent algorithm for time efficient detection of malignant melanoma using dermatofluoroscopy [0.03%]
一种用于高效检测恶性黑色素瘤的智能算法的体内研究
Karl Weihmann,Johannes Schleusener,Thomas K Eigentler et al.
Karl Weihmann et al.
Introduction: Dermatofluoroscopy is an optical non-invasive method of melanoma/nevus differentiation that has shown 89% sensitivity and 45% specificity in clinical trials, but long measurement duration hinders clinical us...