Epidermal Homeostasis in Space from the Stand Point of Keratinocyte Physiology [0.03%]
从角质形成细胞生理角度谈太空中的表皮稳态问题
Mitsuhiro Denda
Mitsuhiro Denda
The human epidermis is the interface between the human body and the environment. It is mainly comprised of keratinocytes. Since the beginning of this century, functional expression of a series of receptors for various environmental factors ...
Oxidative Stress-Mediated Modulation of Fibrosis and Inflammation in Keloid Fibroblasts by Cold Atmospheric Plasma [0.03%]
冷等离子体通过氧化应激调节 keloid 成纤维细胞中的纤维化和炎症反应
Razaul Haque,Sung Eun Chang,Ik Jun Moon
Razaul Haque
Introduction: Despite numerous therapeutic approaches, keloid treatment remains a challenge. Clinical studies have demonstrated the possible use of cold atmospheric plasma (CAP) to treat hypertrophic scars and keloids. Th...
Philip Wesley Wertz
Philip Wesley Wertz
Background: The major carriers of linoleic acid in the epidermis are an acylglucosylceramide in the viable portion of the epidermis and an analogous acylceramide in the stratum corneum. The acylglucosylceramide and acylce...
Kinetic Monitoring of in vitro Release Testing Using UV-Vis Spectrophotometry with Hydrocortisone Creams [0.03%]
体外释放试验的 kinetics 监测——采用 UV-Vis 分光光度法测定氢化可的松软膏
Kelsey Leach,Lola Sibaud,Bradley Towey
Kelsey Leach
Introduction: A new method for conducting in vitro release testing (IVRT) was developed by adapting Higuchi's square root approximation for use with UV-Vis spectrophotometry, and over the counter hydrocortisone formulatio...
Relationships between Skin Structure and Skin Function of Pregnant Women and Their Infants: A Prospective Cohort Study [0.03%]
孕妇及其婴儿皮肤结构与功能关系的前瞻性队列研究
Doris Wilborn,Agathe Franz,Gabriela Engelhardt et al.
Doris Wilborn et al.
In women during pregnancy and in infants during the first months after birth skin health is challenged. However, evidence about the structural and functional changes of the skin during and after pregnancy is largely lacking. The first prosp...
Using Pharmacokinetic Parameters from In Vitro Permeation Test (IVPT) Data for Predicting Multiple Dose Penetration Profiles [0.03%]
基于体外渗透试验参数预测多次给药的渗透曲线
Paul A Lehman
Paul A Lehman
Introduction Several complex mathematical models have been developed using in vitro permeation test [IVPT) data to characterize percutaneous absorption. A less complicated approach, using basic pharmacokinetic parameters on IVPT data, is pr...
Do transdermal administration of α1 and α2 adrenergic receptor antagonists modulate sweating in exercising young females in the heat? [0.03%]
透皮给予α1和α2肾上腺素受体拮抗剂能否调节热环境中年轻女性运动时的排汗反应？
Lu Meng,Hui Wang,Junto Otsuka et al.
Lu Meng et al.
Introduction Adrenergic modulation of sweating remains equivocal in females. We investigated whether α1- and α2-adrenergic receptors can modulate sweating during active heat stress in healthy female participants. Methods Thirty young adul...
Harnessing Artificial Intelligence for Dermatological Care During Space Missions [0.03%]
人工智能在太空任务中用于皮肤病护理的技术探讨
Diala Haykal,Mohamad Goldust
Diala Haykal
Influence of physical, chemical, and sympathetic stimuli on water-immersion finger wrinkling [0.03%]
物理、化学和交感神经刺激对浸水手指皱纹的影响
Bruno D Martimiano,Maria C V Belli,Mariana de R Lai et al.
Bruno D Martimiano et al.
Introduction: Stimulated Skin Wrinkling (SSW) reflects the integrity of the autonomic nervous system, eccrine sweat glands, and microcirculation. Specific stimuli, as water immersion or mechanical pressure usually elicit ...
Bioavailability of Hydroquinone from Topical Formulations: A Product Comparison Study using the In Vitro Permeation Test (IVPT) [0.03%]
氢醌外用制剂的生物利用度比较研究：应用体外透皮吸收试验（IVPT）
Paul A Lehman,Thomas J Franz
Paul A Lehman
Introduction The In Vitro Permeation Test (IVPT) is considered to be an important tool for assessing the topical pharmacokinetics of dermatologic formulations. An IVPT study evaluating products that contain the skin bleaching agent, hydroqu...