Systematic Review of Fatty Acid Composition and the Influence of Coating Media on Fatty Acid Profiles in Canned Fish [0.03%]
鱼类罐头脂肪酸组成的系统性研究及其涂层介质的影响
Ömer Furkan Kaçar,Okba Hatem,Hüsna Kaya Kaçar et al.
Ömer Furkan Kaçar et al.
Canned fish products enable long-term preservation of fish, a vital source of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Despite research on lipid composition, gaps remain in understanding the bidirectional fatty acid (FA) ...
Gastrointestinal Fate and Receptor-Mediated Mechanism of GPSGPQGSR, an Intestinal Barrier-Protective Collagen Peptide from ALASKA Pollock Skin [0.03%]
来源于阿拉斯加鳕鱼皮的肠屏障保护性胶原肽GPSGPQGSR的胃肠命运及其受体介导机制
Qianru Chen,Zheng Zhao,Fengwu Wang et al.
Qianru Chen et al.
Marine-derived collagen peptides exhibit potent intestinal barrier protection; however, their gastrointestinal fate and molecular targets remain unclear, limiting their practical applications. This study investigated the digestive stability...
Three Sulfated Triterpene Glycosides from the Sea Cucumber Psolus phantapus-Biological Activity Against Human Cancer Cell Lines [0.03%]
来源于海参Psolus phantapus的三个糖硫酸三萜及其对人类癌细胞系的生物活性研究
Alexandra S Silchenko,Ekaterina A Chingizova,Ekaterina S Menchinskaya et al.
Alexandra S Silchenko et al.
The glycosidic composition of Psolus phantapus was studied for the first time. Two new glycosides, phantapusosides A (1) and B (2), and the known psolusoside P (3) were isolated and their structures were established by analysis of 1H, 13C N...
Barettin Suppresses Pancreatic Ductal Adenocarcinoma Proliferation via Topoisomerase IIα Inhibition [0.03%]
barettin通过拓扑异构酶IIα抑制作用抑制胰腺导管腺癌增殖
Caleb A Seekins,Monique R Archuleta,Alexandria E Evans et al.
Caleb A Seekins et al.
Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal malignancy with few therapeutic options. Topoisomerase IIα (TOPO2α) is frequently overexpressed in PDAC and is associated with poor clinical outcomes, yet current TOPO2α-dir...
Hemolymph-Mediated Dynamics of Paralytic Shellfish Toxins and Tetrodotoxin in Scallops [0.03%]
甲壳胺介导的麻痹性贝毒和河豚毒素在扇贝体内的动力学特征研究
Ranmaru Matsui,Yuko Cho,Yuta Kudo et al.
Ranmaru Matsui et al.
To investigate the dynamics of paralytic shellfish toxins (PSTs) and tetrodotoxins (TTX) in scallops, PSTs and TTX were analyzed in the hemolymph supernatant (hemolymph-S) and digestive gland in Yesso and Akazara scallops cultured in easter...
Effect of Algal Lectin Siye on Proliferation and Apoptosis of Breast and Colon Cancer Cells [0.03%]
海洋糖蛋白Siye对乳腺癌和结肠癌细胞增殖及凋亡的影响
Xiaobo Zhang,Jianfei Ma,Jiahao Ma et al.
Xiaobo Zhang et al.
Lectins are carbohydrate-binding proteins, some of which exhibit significant anti-tumor activity. Siye is a lectin derived from the red alga Kappaphycus alvarezii that was previously discovered using an artificial intelligence-guided genome...
Green Extraction of Bioactive Compounds from Marine Macroalgae: Chemistry, Pharmacological Activities, and Biotechnological Applications [0.03%]
绿色提取海洋大型藻类生物活性化合物：化学、药理活性及生物技术应用
Yongjing Guan,Yuxin Guo,Luoxuan Lin et al.
Yongjing Guan et al.
Marine macroalgae are widely distributed renewable resources that offer substantial economic and environmental benefits. This review comprehensively examines seaweeds from the phyla Chlorophyta, Heterokontophyta, and Rhodophyta, highlightin...
Marine Lipids and Alzheimer's Disease: Biochemistry, Bioaccessibility/Bioavailability, Metabolism, and Health Effects [0.03%]
海洋脂质与阿尔茨海默病：生物化学、生物可及性/生物利用度、代谢和健康效应
Ana Gomes-Bispo,Carlos Cardoso,Cláudia Afonso et al.
Ana Gomes-Bispo et al.
Due to its high prevalence and significant impact on modern society, Alzheimer's disease (AD) is one of the most important neurodegenerative disorders. It is more common among individuals over the age of 65, and its incidence has increased ...
Quality-by-Design Optimization of Mucoadhesive Trimethyl Chitosan-Coated Alginate/Dextran Sulfate Nanoparticles for Oral Insulin Delivery [0.03%]
用于口服胰岛素递送的粘膜黏附的三甲基壳聚糖包衣的海藻酸/硫酸葡聚糖纳米颗粒的质量-by-设计优化
Bruno Pessoa,Daniel Vanzan,Lucio Cabral et al.
Bruno Pessoa et al.
Trimethyl chitosan (TMC)-coated alginate/dextran sulfate (ADS) nanoparticles were developed as mucoadhesive nanocarriers for oral insulin delivery using a Quality-by-Design strategy. In a first screening step, a two-level factorial design w...
Toxicity Profile of the Oceanic Pufferfish Lagocephalus lagocephalus in the Eastern Atlantic Area [0.03%]
东大西洋海域海洋河豚鱼Lagocephalus lagocephalus的毒性特征分析
Nathália Nocchi,Álvaro Santana-Mayor,Adrián Conde-Díaz et al.
Nathália Nocchi et al.
In recent years, the pufferfish Lagocephalus lagocephalus has been recorded with unusual frequency in coastal areas of the Canary Islands. The most notable episodes occurred in March and November 2017, when numerous shoals were observed alo...