Valorization of Amphidinium carterae for Integrated Preparation of Peridinin and Diadinoxanthin Cycle Carotenoids [0.03%]
从Amphidinium carterae中提取红藻素和二氢双黄酮类胡萝卜素用于联合制备
Yi Li,Gengjie Zhuang,Xuan Zhang et al.
Yi Li et al.
An integrated microalgae biorefinery producing high-purity xanthophylls using a sustainable and efficient strategy still faces critical challenges. In this study, the microalga Amphidinium carterae can accumulate peridinin and diadinoxanthi...
Microbial Blue Bioprospecting: Exploring the Advances of Compounds Post-Discovery [0.03%]
微生物蓝色生物勘探：化合物发现后的研究进展
Cristiana Roberta Multisanti,Valeria Celi,Aurora Dibra et al.
Cristiana Roberta Multisanti et al.
Marine biotechnology is an emerging field of research. There is scientific evidence of the strong potential of a multitude of marine microorganisms in biotechnology, with applications spanning the medical, pharmaceutical, cosmeceutical, nut...
Genomic and Metabolomic Insights into Metabolites of a Streptomyces Isolate Associated with Chromodoris quadricolor, a Red Sea Nudibranch [0.03%]
从红海软体动物Chromodoris quadricolor分离的链霉菌基因组和代谢组学 insights及其代谢物的见解
Samar M Abdelrahman,Zoe A Pratte,Manar El Samak et al.
Samar M Abdelrahman et al.
The marine invertebrate-associated microbiome has garnered significant interest in recent years due to its wealth of novel genes that can be explored for biomining. By combining genomics with untargeted data-dependent mass spectrometry (MS)...
Cancer Cell Cytotoxicity of Marinopyrroles, Pyrrolomycins, and Their Derivatives [0.03%]
海洋生物衍生的马林吡咯类和吡咯霉菌素类及其衍生物对癌细胞的细胞毒性作用研究
Jeffrey M Zimmerly,Nicholas A Armstrong,Clare F Euteneuer et al.
Jeffrey M Zimmerly et al.
Marine-derived secondary metabolites have emerged as a rich potential source of anticancer agents, with marinopyrroles and pyrrolomycins representing structurally distinct halogenated pyrroles of interest. Initially characterized for their ...
New Polyketides and a Ferroptosis Inhibitor from the Marine-Derived Fungus Diaporthe searlei CS-HF-1 [0.03%]
来源于海洋真菌Diaporthe searlei CS-HF-1的新型聚酮类化合物及铁死亡抑制剂研究
Jicheng Xiao,Peng Wu,Yan Zhang et al.
Jicheng Xiao et al.
As a driver of neurodegenerative disorders, ischemic injuries, and acute organ dysfunction, ferroptosis represents a therapeutic target, and its inhibition may provide novel therapies. In our ongoing efforts to discover ferroptosis inhibito...
Novel Discorhabdin Derivatives from Antarctic Sponges of the Genus Latrunculia: Expanding the Chemical Diversity of Polar Marine Natural Products [0.03%]
南极_LATRUNCULIA_属海绵中新型discorhabdins衍生物：极地海洋天然产物化学多样性的扩展
Sam Afoullouss,Stine S H Olsen,Sydney Morrow et al.
Sam Afoullouss et al.
In this study, three Antarctic sponges of the genus Latrunculia were investigated, leading to the isolation of five unreported pyrroloiminoquinone alkaloids along with the known metabolite (+)-debromodiscorhabdin A (3). Three of the new met...
Recent Advances in Secondary Metabolites from Marine Aspergillus [0.03%]
recent advances in次生代谢产物从海洋曲霉菌中获得
Zimin Wang,Meirong Zhao,Chenglin Li et al.
Zimin Wang et al.
Marine Aspergillus fungi, adapted to extreme marine environments (e.g., sediments, corals, mangroves), are prolific producers of structurally diverse secondary metabolites with significant bioactivities. This review comprehensively analyzes...
Marine-Derived Steroids for Cancer Treatment: Search for Potential Selective Glucocorticoid Receptor Agonists/Modulators (SEGRAMs) [0.03%]
海洋甾体抗肿瘤药物的研发：寻找潜在的选择性糖皮质激素受体激动剂/调制剂(SEGRAMs)
Ekaterina M Zhidkova,Ekaterina D Savina,Ekaterina A Yurchenko et al.
Ekaterina M Zhidkova et al.
Steroids, particularly glucocorticoids, are essential components of cancer treatment for both hematological malignancies and solid tumors. The adverse effects of standard steroid-based drugs have forced drug discovery research to develop ch...
Methodologies for Detoxifying Bivalves from Marine Paralytic Shellfish Toxins [0.03%]
脱毒双壳贝类中麻痹性贝毒的方法学研究进展
Adewale Aderogba,Joana F Leal,Maria L S Cristiano
Adewale Aderogba
The marine environment emerges as a key provider of food and sustainable products. However, these benefits are accompanied by numerous challenges owing to harmful algal blooms (HAB) and their associated biotoxins, which accumulate in organi...
Insights into the Bioactivities and Mechanism of Action of the Microbial Diketopiperazine Cyclic Dipeptide Cyclo(L-leucyl-L-prolyl) [0.03%]
微生物二酮哌嗪环肽Pro-Leu的生物活性及机制研究
Christian Bailly
Christian Bailly
Diketopiperazines (DKPs) are biologically important cyclic dipeptides widespread in nature, associated primarily with microorganisms. This is the case for the 2,5-DKP derivative cyclo(L-Leu-L-Pro) (cLP), also known as gancidin W or PPDHMP, ...