Bioactive Glycosaminoglycans from Caranx crysos: A Structure-Function Study of Selective Anticoagulant Activity [0.03%]
结构和功能研究：Caranx crysos的生物活性糖胺聚糖对选择性抗凝血活性的影响研究
Ranim Kroumi,Soumaya Alimi,Fabiana Esposito et al.
Ranim Kroumi et al.
Glycosaminoglycans (GAGs) are the carbohydrate portion of proteoglycans (PGS), a family of complex biomacromolecules ubiquitously found in the extracellular matrix and on cell surfaces that play critical roles in a plethora of physiological...
Low-Molecular-Weight Fish Collagen Peptide Enhances Hair Regrowth via Activation of Proliferative Signaling and Suppression of Inhibitory Pathways [0.03%]
低分子量鱼胶原肽通过激活增殖信号和抑制抑制途径促进头发生长
Hyelim Kim,Yeonhwa Lee,Seong-Hoo Park et al.
Hyelim Kim et al.
Collagen peptides have been widely studied for their beneficial effects on skin health; however, their potential role in hair growth remains insufficiently explored. This study aimed to investigate the effects of orally administered low-mol...
Fucoidan Attenuates Lead-Induced Liver Injury Associated with IGFBP1 and Gut Microbiota-Derived Tryptophol Metabolism [0.03%]
岩藻糖甘露聚糖通过IGFBP1和肠道微生物来源的色氨酸代谢缓解铅诱导肝损伤
Dianzun Liu,Kaiyu Shen,Jiaxin Li et al.
Dianzun Liu et al.
Lead (Pb) exposure induces liver injury through oxidative stress, inflammation, and gut-liver axis disruption. This study evaluated the protective effects and associated mechanisms of fucoidan (FU) against Pb-induced liver injury in mice. C...
Cathepsin B-Oriented Screening, Isolation, and Antitumor Validation of Bioactive Metabolites from Sargassum polycystum [0.03%]
从萨尔格萨穆属多囊藻中筛选、分离并验证其半胱氨酸蛋白酶B导向的抗肿瘤活性代谢产物
Wanchao Hou,Lingqiu Zhang,Kai Yu et al.
Wanchao Hou et al.
Marine medicinal algae represent a valuable reservoir of bioactive metabolites for anticancer drug discovery, yet the efficient identification of target-relevant compounds from chemically complex marine matrices remains challenging. In this...
Molecular Pathway and Regulatory Mechanism of the Saponin Biosynthesis in Sea Cucumber Apostichopus japonicus [0.03%]
刺参皂苷合成的分子途径和调控机制研究
Pingzhe Jiang,Shan Gao,Yujun Liu et al.
Pingzhe Jiang et al.
Sea cucumber Apostichopus japonicus is one of the few animals capable of synthesizing saponins, which are critical components of its nutritional quality and health-beneficial properties. However, the specific mechanism underlying saponin bi...
Salicornia europaea L. as a Marine Bioactive Resource: Phytochemical Profile, Health Mechanisms, and Functional Applications in Precision Nutrition [0.03%]
欧洲盐角草（Salicornia europaea L.）作为海洋活性生物资源的植物化学成分、健康机制及其在精准营养中的功能性应用
José Francisco Tornero-Aguilera,Carlota Valeria Villanueva-Tobaldo,Edgar Simón Sancho-Haro et al.
José Francisco Tornero-Aguilera et al.
Marine halophytes are gaining attention as a source of plant-derived bioactive compounds with potential applications across nutraceuticals, functional foods, and preventive nutrition. Among them, Salicornia europaea L. is a coastal succulen...
Screening of Microalgal Species for Biostimulant and Biofertilizer Applications [0.03%]
微藻生物刺激素和生物肥料应用的筛选研究
Eirini Sventzouri,Eleni Pagkaki,Sotirios Zerveas et al.
Eirini Sventzouri et al.
Microalgae represent a promising alternative as biofertilizers and biostimulants, providing essential nutrients and bioactive compounds that support plant growth. In this study, a screening of seven microalgal species-including Arthrospira ...
GC-MS-Based Metabolomics Provides Insights into the Biochemical Peculiarity of Seven Brown Algal Species of the Order Fucales [0.03%]
基于GC-MS的代谢组学揭示了七种墨褐藻目的褐藻的生化特性
Elena Tarakhovskaya,Ekaterina Gulk,Bochao Yang et al.
Elena Tarakhovskaya et al.
Brown algae are important primary producers in coastal ecosystems, where they provide habitat and food for numerous marine species. For humans, they provide raw materials (food, animal feed, and ingredients for pharmaceuticals and cosmetics...
Multi-Omics-Guided Discovery of Holothuria scabra-Derived Drug Candidates Targeting Ferroptosis and the Bone Tumor Microenvironment in Osteosarcoma [0.03%]
基于多组学的海参来源的靶向铁死亡和骨肿瘤微环境的治疗骨肉瘤药物候选物发现
Jeremy Nicolas Sibarani,Mohammad Adib Khumaidi,Yudha Mathan Sakti et al.
Jeremy Nicolas Sibarani et al.
Osteosarcoma remains the most common primary malignant bone tumor in adolescents and is characterized by aggressive metastasis, resistance to therapy, and extensive bone microenvironment remodeling. Therefore, the identification of novel mu...
Microparticles Based on Chitosan/Xanthan Gum Polyelectrolyte Complex Modulate the Anti-Inflammatory and Antinociceptive Effects of Ibuprofen and Escin [0.03%]
基于壳聚糖/黄原胶聚电解质复合物的微粒调节布洛芬和七叶皂苷钠的抗炎镇痛作用
Ana Ćirić,Nikola Martić,Milana Bosanac et al.
Ana Ćirić et al.
Polyelectrolyte complex (PEC)-based carriers offer a promising strategy to improve the oral delivery of anti-inflammatory agents with limited bioavailability or variable pharmacodynamic profiles. This study evaluated the anti-inflammatory a...