Ecological Validity of the Montreal Cognitive Assessment in Non-Demented Parkinson's Disease Patients [0.03%]
蒙特利尔认知评估量表在非痴呆帕金森病患者中的生态效度研究
Edoardo Nicolò Aiello,Alfonsina D&#x;Iorio,Federica Solca et al.
Edoardo Nicolò Aiello et al.
Background: The ecological validity of performance-based cognitive screeners needs to be tested in order for them to be fully recommended for use within clinical practice and research. ...
CSF Aβ40 Levels Do Not Correlate with the Clinical Manifestations of Alzheimer's Disease [0.03%]
脑脊液Aβ40水平与阿尔茨海默病的临床表现无关
Jesús Garcia Castro,Helena Méndez Del Sol,Olaia Rodríguez Fraga et al.
Jesús Garcia Castro et al.
Introduction: Cerebrospinal fluid (CSF) biomarker quantification provides physicians with a reliable diagnosis of Alzheimer's disease (AD). However, the relationship between their concentration and disease course has not ...
The Two-Way Route between Delirium Disorder and Dementia: Insights from COVID-19 [0.03%]
谵妄障碍和痴呆的双向关系：来自COVID-19的启示
Giulia Bommarito,Valentina Garibotto,Giovanni B Frisoni et al.
Giulia Bommarito et al.
Background: Delirium disorder is a frequent neurological complication of SARS-CoV-2 infection and associated with increased disease severity and mortality. Cognitive impairment is a major risk factor for developing deliri...
Clinical Manifestations Associated with the Domain-Containing Protein 2 Gene Mutation in an Iranian Family with Spastic Paraplegia 54 [0.03%]
与域含蛋白2基因突变相关的伊朗家族遗传性痉挛性截瘫的临床表现
Abolfazl Yari,Shokoofeh Etesam,Shannaz Zarifi et al.
Abolfazl Yari et al.
Introduction: Spastic paraplegia type 54 (SPG54) is an autosomal recessive disorder caused by bi-allelic mutations in the DDHD-domain-containing protein 2 (DDHD2) gene. Worldwide, over 24 SPG54 families and 24 pathogenic ...
Age of Onset and Length of Survival of Queensland Patients with Amyotrophic Lateral Sclerosis: Details of Subjects with Early Onset and Subjects with Long Survival [0.03%]
肌萎缩性侧索硬化症昆士兰患者发病年龄和生存期长度：早期发病患者和长期生存患者的详细信息
Robert J Nona,Zhouwei Xu,Gail A Robinson et al.
Robert J Nona et al.
Introduction: The aims of the study were to document the characteristics of amyotrophic lateral sclerosis (ALS) patients in Queensland, to examine factors influencing age of onset, and survival, and to study those with ea...
The Immunomodulatory Potential Role of Mesenchymal Stem Cells in Diseases of the Central Nervous System [0.03%]
间充质干细胞在中枢神经系统疾病中的免疫调节作用潜力
Rodrigo de Andrade Rufino,Laís da Silva Pereira-Rufino,Thays Cristina Silva Vissoto et al.
Rodrigo de Andrade Rufino et al.
Introduction: Several studies indicate the role of mesenchymal stem cells (MSCs) as an important tool in regenerative medicine associated with injuries that affect the central nervous system (CNS). The MSCs have the capac...
Natural Age-Related Slow-Wave Sleep Alterations Onset Prematurely in the Tg2576 Mouse Model of Alzheimer's Disease [0.03%]
APP/PS1小鼠阿尔茨海默病模型中天然衰老相关的慢波睡眠的变化提早发生
Sedef Kollarik,Inês Dias,Carlos G Moreira et al.
Sedef Kollarik et al.
Introduction: Sleep insufficiency or decreased quality have been associated with Alzheimer's disease (AD) already in its preclinical stages. Whether such traits are also present in rodent models of the disease has been po...
4-Phthalimidobenzenesulfonamide Derivatives as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: DFTs, 3D-QSAR, ADMET, and Molecular Dynamics Simulation [0.03%]
基于DFT、三维QSAR、ADMET及分子动力学模拟的乙酰胆碱酯酶和丁酰胆碱酯酶抑制剂-对苯磺酰胺类衍生物的研究
Syeda Abida Ejaz,Ammara Fayyaz,Hafiz Mohammad Kashif Mahmood et al.
Syeda Abida Ejaz et al.
Introduction: Alzheimer's disease is a form of dementia which affects majority of the people. It is characterized by memory loss and other cognitive function disabilities and is one of the most challenging neurodegenerati...
CSF Aβ40 and P-Tau181 Might Differentiate Atypical from Typical AD Phenotypes: Preliminary Evidence [0.03%]
脑脊液Aβ40和P-tau181可能用于区分非典型和典型的阿尔茨海默病：初步证据
Federico Verde,Edoardo Nicolò Aiello,Eleonora Giacopuzzi Grigoli et al.
Federico Verde et al.
Objectives: This study aimed at testing whether CSF levels of amyloid β42 (Aβ42), Aβ40, total tau, and phosphorylated tau (P-tau181) individually contribute to the identification of atypical phenotypes among a retrospe...
Association between Gut Microbiota with Mild Cognitive Impairment and Alzheimer's Disease in a Thai Population [0.03%]
泰国人群中轻度认知障碍和阿尔茨海默病的肠道微生物群的相关性
Pagakrong Wanapaisan,Mallika Chuansangeam,Saifon Nopnipa et al.
Pagakrong Wanapaisan et al.
Background: Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are common in older adults. Much recent work has implicated the connection between the gut and the brain via bidirectional communication of the gast...