White Matter Hyperintensities Are Associated with Slower Gait Speed in Older Adults without Dementia [0.03%]
白质高信号与无痴呆老年人步行速度减慢有关
Juan P Vazquez,Joe Verghese,Nir Barzilai et al.
Juan P Vazquez et al.
Introduction: Slow gait speed is associated with poor health outcomes in aging, but the relationship between cerebral small vessel disease (CSVD) pathologies and gait speed in aging is not well understood. We investigated...
Baseline Depressive Symptoms as a Predictor of Incident Dementia in a Prospectively Followed Cohort of Elders with Essential Tremor [0.03%]
基线抑郁症状作为特发性震颤老年人群继发痴呆的预测因素：前瞻性队列研究
Diane S Berry,Ali Ghanem,Margaret M McGurn et al.
Diane S Berry et al.
Introduction: Essential tremor (ET) patients may exhibit a variety of non-motor features, including cognitive decline and depressive symptoms. Studies of several neurodegenerative diseases link depression to cognitive dec...
The Impact of Drug Interactions on the results of DAT-SPECT Imaging in a Specialty Movement Disorders Practice: A Retrospective Analysis of Outcomes [0.03%]
药物相互作用对专科运动障碍实践中DAT-SPECT影像结果的影响：结果的回顾性分析
Isabelle Heewon Kang,Danny Bega
Isabelle Heewon Kang
Introduction: DAT-SPECT imaging is approved as a diagnostic tool for the evaluation of suspected Parkinsonian syndromes, but the FDA approved package insert lists 16 potential drugs that may interfere with the image obtai...
Whole Exome Sequencing Indicating GGCCTG Hexanucleotide Repeat in Patients with Spinocerebellar Ataxia Type 36 [0.03%]
脊髓小脑性共济失调36型患者外显子组测序提示GGCCTG六核苷酸重复序列扩张
Ran Chen,Chao Zhou,Yun Peng et al.
Ran Chen et al.
Introduction: Spinocerebellar ataxia type 36 (SCA36) is caused by large GGCCTG repeat expansion in the NOP56 gene. The genetic diagnosis based on Southern blot is expensive and time-consuming. This study aimed to evaluate...
Classification of Mild Cognitive Impairment and Alzheimer's Disease Using Manual Motor Measures [0.03%]
基于手动运动指标的轻度认知障碍和阿尔茨海默病分类研究
Vincent Koppelmans,Marit F L Ruitenberg,Sydney Y Schaefer et al.
Vincent Koppelmans et al.
Introduction: Manual motor problems have been reported in mild cognitive impairment (MCI) and Alzheimer's disease (AD), but the specific aspects that are affected, their neuropathology, and potential value for classificat...
Subjective Sleep Disturbance and Lewy Pathology: Data from a Cohort of Essential Tremor Brain Donors [0.03%]
主观性睡眠障碍与路易病理损害：来自原发性震颤脑捐赠者队列的数据分析
Ali Ghanem,Diane S Berry,Stephanie Cosentino et al.
Ali Ghanem et al.
Introduction: Sleep disturbances have been associated with essential tremor (ET). However, their pathophysiological underpinnings remain unknown. In this exploratory study, we examined the association between subjective s...
Potential Correlation between Tea Intake and the Risk of Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study [0.03%]
基于孟德尔随机化研究的喝茶与运动神经元病关联的潜在因果关系分析
Jinyue Li,Songyu Li,Guoqiang Fei
Jinyue Li
Introduction: There were limited observation studies on the association between tea intake and amyotrophic lateral sclerosis (ALS) with inconsistent results. This study aimed to determine the potential relationship betwee...
20th Anniversary of Neurodegenerative Diseases: A Parallel (R)Evolution between the 20th and the 21st Century? [0.03%]
神经退行性疾病研究二十年——一个二十世纪与二十一世纪并行的（逆）向进化？
Gilles Allali
Gilles Allali
The Taxonomy of Subjective Cognitive Decline: Proposal and First Clinical Evidence from the Geneva Memory Clinic Cohort [0.03%]
基因申记忆门诊队列的主观认知衰退分类及其初步临床证据
Federica Ribaldi,Rafael Palomo,Daniele Altomare et al.
Federica Ribaldi et al.
Introduction: Subjective cognitive decline (SCD) is characterized by subjective cognitive concerns without objective cognitive impairment and is considered a risk factor for cognitive decline and dementia. However, most S...
A Decision-Making Algorithm for Remote Digital Assessments of Alzheimer's Disease [0.03%]
一种用于远程数字评估阿尔茨海默病的决策算法
Valeria Manera,Clair Vandersteen,Alexandra Plonka et al.
Valeria Manera et al.
Introduction: Remote digital assessments (RDAs) such as voice recording, video and motor sensors, olfactory, hearing, and vision screenings are now starting to be employed to complement classical biomarker and clinical ev...