Locus Coeruleus sexual dimorphism and its impact on cognitive impairment and cortical atrophy in Alzheimer's Disease [0.03%]
蓝斑的性别二态性及其对阿尔茨海默病认知障碍和皮层萎缩的影响
Alessandro Galgani,Francesco Lombardo,Francesca Frijia et al.
Alessandro Galgani et al.
Introduction: Experimental data suggest sexual dimorphism in the Locus Coeruleus (LC), with females exhibiting higher neuronal count and noradrenergic activity. In Alzheimer's Disease (AD), progressive LC dysfunction may ...
Huntington's Disease in Hospitalized Patients Infected with SARS-CoV-2 in Brazil: Three-Year Update [0.03%]
巴西住院的SARS-CoV-2感染患者中的亨廷顿病:三年更新报告
Jéssica Paula Martins,Juliana Mozer Sciani,Fernando Augusto Lima Marson
Jéssica Paula Martins
Introduction: Huntington's disease (HD) is considered a rare and fatal neurodegenerative disease; despite that, only one study described the outcomes among those with HD and COVID-19. In this context, an epidemiological i...
A review of sex differences in neurodegeneration and psychological comorbidities in MS and related disorders [0.03%]
多发性硬化症及相关疾病中神经变性和心理共病性别差异的综述
Jelena Brasanac,Josephine Heine,Claudia Chien
Jelena Brasanac
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are chronic neuroinflammatory conditions that disproportionately affect women, with a 2:1 ratio in MS and up to 8.9:1 in NMOSD. Cognitive impairment is one of the ea...
Differential effects of disease duration and dopaminergic replacement therapy on vocal emotion recognition in asymmetric Parkinson's disease [0.03%]
帕金森病病程和多巴胺能替代治疗对不对称性帕金森病患者情绪识别的影响不同
Philippe Voruz,Didier Grandjean,Sophie Drapier et al.
Philippe Voruz et al.
Introduction: Recently, studies have suggested a role of motor symptom asymmetry on impaired emotional recognition abilities in Parkinson's disease with a greater vulnerability in patients with a predominance of left-side...
Anti-amyloid drugs for Alzheimer's disease: considering the role of depression [0.03%]
阿尔茨海默病的抗淀粉样蛋白药物:考虑抑郁症的作用
Beatriz Pozuelo Moyano,Leonardo Zullo,Olivier Rouaud et al.
Beatriz Pozuelo Moyano et al.
Depressive symptoms are the second most common neuropsychiatric symptom (NPS) in dementia, and there are compelling arguments linking depression and amyloid deposition in the brain. Clinical trials on anti-amyloid treatment are primarily fo...
Serum Neurofilament Light-Chain Levels in Essential Tremor: A Replication Study [0.03%]
特发性震颤患者血清神经丝轻链水平的验证研究
Elan D Louis,Vibhash D Sharma,Ihab Hajjar et al.
Elan D Louis et al.
Introduction: Essential tremor (ET) is a highly-prevalent neurological disease. At present, there are no clinical biomarkers. Neurofilament light (NfL) has been studied as a measure of neuronal damage in a considerable nu...
Neurology of Aging: Adapting Neurology Provision for an Aging Population [0.03%]
神经病学与老龄化:适应老年人口的神经系统疾病诊疗方法
Patrick Stancu,Lisa Hentsch,Margitta Seeck et al.
Patrick Stancu et al.
Background: Over the past few decades, advances in the neurology of aging have been considerable and have led to a better understanding of the science of age-related neurological disorders. Likewise, it changed the percep...
Distinct Patterns of Brain Atrophy in Amnestic Mild Cognitive Impairment and Motoric Cognitive Risk Syndromes [0.03%]
遗忘性轻度认知障碍和运动性轻度认知障碍的脑萎缩模式不同
Vineela Nagamalla,Joe Verghese,Emmeline Ayers et al.
Vineela Nagamalla et al.
Introduction: Motoric cognitive risk (MCR) and amnestic mild cognitive impairment (aMCI) syndromes are each reliable predictors of incident Alzheimer's disease (AD), but MCR may be a stronger predictor of vascular dementi...
Dual-Task Performance and Brain Morphologic Characteristics in Parkinson's Disease [0.03%]
帕金森病的双任务表现和脑形态特征
Sarah J Carlson,Yi-Fang Chiu,Merrill R Landers et al.
Sarah J Carlson et al.
Introduction: Parkinson's disease (PD) reduces an individual's capacity for automaticity which limits their ability to perform two tasks simultaneously, negatively impacting daily function. Understanding the neural correl...