Association between Excessive Daytime Sleepiness and the Cholinergic Ascending Reticular System in Parkinson's Disease [0.03%]
日间过度睡眠与帕金森病胆碱能上行网状系统的关联研究
Mutsumi Iijima,Mikio Osawa,Sayuri Yasuda et al.
Mutsumi Iijima et al.
Background: Excessive daytime sleepiness (EDS) in Parkinson's disease (PD) may occur because of dysfunction on the brain areas in controlling wakefulness; however, the pathophysiology of EDS in PD has not been completely ...
Characteristics of Late-Onset Amyotrophic Lateral Sclerosis in a Chinese Cohort [0.03%]
中国ALS患者晚发型的特点分析
Qionghua Sun,Yunyun Huo,Jiongming Bai et al.
Qionghua Sun et al.
Objective: This retrospective study analyzed the clinical characteristics and prognosis of the elderly amyotrophic lateral sclerosis (ALS) population in a large sample. ...
The Effects of 8-Week Combined Exercise Training on Inflammatory Markers in Women with Multiple Sclerosis [0.03%]
八周联合锻炼训练对多发性硬化女性患者炎症标志物的影响
Fahime Tadayon Zadeh,Hamid Amini,Saeed Habibi et al.
Fahime Tadayon Zadeh et al.
Purpose: The present study was designed to investigate the effects of 8-week combined endurance, resistance, and balance exercise training on IL-6, CRP, and IL-10 concentrations in women with multiple sclerosis. ...
Elevated Levels of Homocysteinesulfinic Acid in the Plasma of Patients with Amyotrophic Lateral Sclerosis: A Potential Source of Excitotoxicity? [0.03%]
肌萎缩侧索硬化患者血浆中高同型半胱氨酸硫酸酸水平升高：兴奋毒性潜在来源？
Aven Lee,Buddhika Jayakody Arachchige,Robert Henderson et al.
Aven Lee et al.
Objectives: Excitotoxicity is thought to be involved in the pathogenesis of amyotrophic lateral sclerosis (ALS). One possible source of excitotoxicity is the presence of sulphur amino acids (SAAs). In the brain of subject...
Extending the Spectrum of Nonmotor Symptoms with Olfaction in Premotor Huntington's Disease: A Pilot Study [0.03%]
前运动亨廷顿病嗅觉非运动症状谱系扩展的试点研究
Beatrice Heim,Dora Valent,Federico Carbone et al.
Beatrice Heim et al.
Objective: The aim of this pilot study was to investigate change of olfactory functions in Huntington's disease (HD). Background: HD is...
The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline [0.03%]
新冠肺炎大流行对痴呆症风险的影响：认知衰退的潜在途径
Jeffrey D Pyne,Adam M Brickman
Jeffrey D Pyne
Background: Coronavirus disease 2019 (COVID-19), the far-reaching pandemic, has infected approximately 185 million of the world's population to date. After infection, certain groups, including older adults, men, and peopl...
Computerized Simple Reaction Time and Balance in Nondemented Parkinson's Patients [0.03%]
计算机化简单反应时间和非痴呆帕金森患者的平衡关系
Aida Arroyo-Ferrer,Jorge Andreo,José A Periáñez et al.
Aida Arroyo-Ferrer et al.
Background: Parkinson's disease (PD) patients are known to suffer from subtle cognitive and balance deficits from the early stages although they usually manifest in advanced stages. Postural instability (PI) has been corr...
Laura E Ramos-Languren,Roberto Rodríguez-Labrada,Jonathan J Magaña et al.
Laura E Ramos-Languren et al.
Background: Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant disorder caused by a mutation in the ATXN7 gene. The involvement of the brainstem auditory pathway in pathogenesis of this disease has not been sys...
Prevalence of Gastrointestinal Symptoms, Severity of Dysphagia, and Their Correlation with Severity of Amyotrophic Lateral Sclerosis in a Mexican Cohort [0.03%]
墨西哥队列中肌萎缩侧索硬化患者胃肠症状的流行率及其与疾病严重程度的相关性
Carolina Parra-Cantu,Arnulfo Zaldivar-Ruenes,Manuel Martinez-Vazquez et al.
Carolina Parra-Cantu et al.
Objectives: Our study aimed to identify the prevalence and severity of gastrointestinal (GI) symptoms and dysphagia in patients with amyotrophic lateral sclerosis (ALS) and to assess whether a correlation exists between t...
Cerebrospinal Fluid Alzheimer's Biomarkers and Neurofilament Light Profile of Idiopathic Normal Pressure Hydrocephalus in China: A PUMCH Cohort Study [0.03%]
中国北京协和医院队列特发性正常压力脑积水的阿尔茨海默病生物标志物及神经丝光蛋白谱特征：一项PUMCH队列研究
Chenhui Mao,Longze Sha,Caiyan Liu et al.
Chenhui Mao et al.
Introduction: Idiopathic normal pressure hydrocephalus (iNPH) is one of the potentially reversible dementias. Early and accurate diagnosis is important for patients' prognosis. Emerging evidence shows fluid biomarkers are...