Renal Oxygenation Characteristics in Healthy Native Kidneys: Assessment with Blood Oxygen Level-Dependent Magnetic Resonance Imaging [0.03%]
健康原肾的肾脏氧合特性：应用血液氧水平依赖性磁共振成像评估
Zhenfeng Zheng,Huilan Shi,Hui Ma et al.
Zhenfeng Zheng et al.
Objective: To explore the characteristics of blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI) in healthy native kidneys. Methods: ...
Impact of aldosterone on osteoinductive signaling and vascular calcification [0.03%]
醛固酮对成骨诱导信号和血管钙化的影响
Florian Lang,Eberhard Ritz,Ioana Alesutan et al.
Florian Lang et al.
Vascular calcification is frequently found already in early stages of chronic kidney disease (CKD) patients and is associated with high cardiovascular risk. The process of vascular calcification is not considered a passive phenomenon but in...
Ferruh Artunc,Florian Lang
Ferruh Artunc
Effects of mineralocorticoids are not restricted to regulation of epithelial salt transport, extracellular volume and blood pressure; mineralocorticoids also influence a wide variety of seemingly unrelated functions such as inflammation and...
Carsten A Wagner
Carsten A Wagner
Aldosterone is classically associated with the regulation of salt and potassium homeostasis but has also profound effects on acid-base balance. During acidosis, circulating aldosterone levels are increased and the hormone acts in concert wi...
Genetic, molecular and clinical determinants for the involvement of aldosterone and its receptors in major depression [0.03%]
遗传、分子和临床决定因素与醛固酮及其受体在重大抑郁障碍中作用的关系
Harald Murck,Matthias Büttner,Tilo Kircher et al.
Harald Murck et al.
Major depression (MDE) has metabolic and neuroendocrine correlates, which point to a biological overlap between MDE and cardiovascular diseases. Whereas the hypothalamic-pituitary-adrenocortical axis has long been recognized for its involve...
Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms [0.03%]
盐皮质激素引起的摄钠行为和肾脏保盐作用：相同信号和效应机制的证据
Yiling Fu,Volker Vallon
Yiling Fu
An increase in renal sodium chloride (salt) retention and an increase in sodium appetite are the body's responses to salt restriction or depletion in order to restore salt balance. Renal salt retention and increased sodium appetite can also...
Florian Lang
Florian Lang
Classical effects of mineralocorticoids include stimulation of Na(+) reabsorption and K(+) secretion in the kidney and other epithelia including colon and several glands. Moreover, mineralocorticoids enhance the excretion of Mg(2+) and rena...
Insulin Receptor and the Kidney: Nephrocalcinosis in Patients with Recessive INSR Mutations [0.03%]
胰岛素受体与肾脏：INSR基因突变患者的肾钙质沉积病
Arabella Simpkin,Elaine Cochran,Fergus Cameron et al.
Arabella Simpkin et al.
Background/aims: Donohue and Rabson-Mendenhall syndrome are rare autosomal recessive disorders caused by mutations in the insulin receptor gene, INSR. Phenotypic features include extreme insulin resistance, linear growth ...
Ernest Henry Starling (1866-1927) on the glomerular and tubular functions of the kidney [0.03%]
埃亨利·斯坦利（1866-1927）论肾脏的滤过和管状功能
Leon G Fine
Leon G Fine
Around the turn of the 20th century, Ernest Henry Starling (1866-1927) made many fundamental contributions to the understanding of human physiology. With a deep interest in how fluid balance is regulated, he naturally turned to explore the ...
Ernest Henry Starling (1866-1927) on the formation and reabsorption of lymph [0.03%]
埃亨·斯塔林（1866－1927）论淋巴的生成和重吸收
Leon G Fine
Leon G Fine
Ernest Henry Starling laid the groundwork for our modern understanding of how the interstitial fluid, which he referred to as 'lymph', is regulated. Together with his colleague, William Bayliss, he provided the crucial insight into how flui...