Chemoprevention with phytochemicals targeting inducible nitric oxide synthase [0.03%]
以诱导型一氧化氮合酶为靶点的植物化学成分癌变预防作用研究进展
Akira Murakami
Akira Murakami
A regulated low level of nitric oxide (NO) production in the body is essential for maintaining homeostasis (neuroprotection, vasorelaxation, etc.), though certain pathophysiological conditions associated with inflammation involve de novo sy...
Ginger-derived phenolic substances with cancer preventive and therapeutic potential [0.03%]
具有防癌和治疗潜力的姜原生酚类物质
Joydeb Kumar Kundu,Hye-Kyung Na,Young-Joon Surh
Joydeb Kumar Kundu
Ginger, the rhizomes of Zingiber officinale Roscoe (Zingiberaceae), has widely been used as a spice and condiment in different societies. Besides its food-additive functions, ginger has a long history of medicinal use for the treatment of a...
Chemoprevention by isothiocyanates: molecular basis of apoptosis induction [0.03%]
异硫氰酸盐的化学预防作用：诱导凋亡的分子机理
Yoshimasa Nakamura
Yoshimasa Nakamura
An important and promising group of compounds that have a cancer-chemopreventive property are organosulfur compounds, such as isothiocyanates (ITCs). Various ITCs are effective chemoprotective agents against chemical carcinogenesis in exper...
Molecular basis for cancer chemoprevention by green tea polyphenol EGCG [0.03%]
绿茶儿茶素EGCG的化学预防癌症的作用机理研究
Hirofumi Tachibana
Hirofumi Tachibana
For the past two decades, many researchers have been investigating the potential cancer-preventive and therapeutic effects of green tea. (-)-Epigallocatechin-3-O-gallate (EGCG) has been shown to be the most active and major polyphenolic com...
Exercise and food factors [0.03%]
运动与饮食因素
Wataru Aoi
Wataru Aoi
Habitual exercise is beneficial to health as it improves metabolism, reduces the risk of cardiovascular disease, and maintains the immune system. Appropriate nutrition contributes to acceleration of health promotion due to exercise. Recomme...
Kazuo Miyashita
Kazuo Miyashita
Although an effort is made to review marine carotenoids as important bioactive compounds with reference to their presence, and chemical and biofunctional benefits, there has been a relatively little information on the impact of these carote...
Astaxanthin protects neuronal cells against oxidative damage and is a potent candidate for brain food [0.03%]
虾青素能保护神经细胞免受氧化损伤并可作为脑部保健品的强力候选物
Xuebo Liu,Toshihiko Osawa
Xuebo Liu
Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living organisms. Based on the report claiming that AST could cross the brain-blood barrier, the aim of this study was to investigate the neuroprotective...
Geun Eog Ji
Geun Eog Ji
The incidence of allergic diseases has been increasing in industrialized countries during recent years. Although several environmental factors are thought be involved, lack of moderate level of microbial challenges during the infantile peri...
Yoshiko Ishimi
Yoshiko Ishimi
Soybean isoflavones are structurally similar to estrogen, bind to estrogen receptors, and exhibit weak estrogenic activity. It has been reported that isoflavones play an important role in the prevention of hormone-dependent diseases, includ...
Inflammatory components of adipose tissue as target for treatment of metabolic syndrome [0.03%]
针对代谢综合征的炎症性脂肪组织靶向治疗
Rina Yu,Chu-Sook Kim,Ji-Hye Kang
Rina Yu
Obesity is an independent risk factor in the etiology of various metabolic diseases such as insulin resistance, type 2 diabetes and cardiovascular diseases. In this chapter, we discuss obesity-induced inflammation as a potential link with o...