I Elmadfa,A Meyer,V Nowak et al.
I Elmadfa et al.
I Elmadfa
I Elmadfa
Marion M Hetherington,Joanne E Cecil
Marion M Hetherington
Obesity is a global and growing problem. The detrimental health consequences of obesity are significant and include co-morbidities such as diabetes, cancer and coronary heart disease. The marked rise in obesity observed over the last three ...
E L Sullivan,K L Grove
E L Sullivan
Increasing evidence indicates that early metabolic programming contributes to escalating obesity rates in children and adults. Metabolic imprinting is involved in the establishment of set points for physiologic and metabolic responses in ad...
Eric Stice,Alain Dagher
Eric Stice
Dopamine-based reward circuitry appears to play a role in encoding reward from eating and incentive sensitization, whereby cues associated with food reward acquire motivational value. Data suggest that low levels of dopamine D2 receptors an...
Morten L Kringelbach,Alan Stein
Morten L Kringelbach
The hedonic component of eating is an underexplored topic within neuroscience, which is surprising given its importance for our survival and general well-being, as well as the obvious links to obesity and eating disorders. Based on findings...
Marianne T Neary,Rachel L Batterham
Marianne T Neary
The notion that eating is intimately related to feelings of pleasure is not new. Indeed, in an environment characterised by many varied and palatable foods, hedonistic drives are likely to play a greater role in modulating food intake than ...
Brainstem integrative function in the central nervous system control of food intake [0.03%]
脑干在中枢神经系统摄食调控中的整合功能研究进展
Gary J Schwartz
Gary J Schwartz
The caudal brainstem lies at a critical nexus in the neural hierarchy that helps determine the negative feedback control of ingestion. It is the first central nervous system site that receives neural input from vagal and nonvagal visceral a...
James E Blevins,Denis G Baskin
James E Blevins
It is now axiomatic that neurons in the hypothalamic arcuate nucleus have a primary role in responding to changes in circulating levels of leptin and transmitting signals to downstream circuits that influence eating and energy expenditure. ...
Heike Münzberg
Heike Münzberg
Leptin acts as an anorexigenic hormone in the brain, where the long form of the leptin receptor (LRb) is widely expressed in hypothalamic and extra-hypothalamic sites that are known to participate in diverse feeding circuits. The important ...