Jacquelien J G Hillebrand,Nori Geary
Jacquelien J G Hillebrand
The physiological regulation of adiposity is supposed to depend on endocrine 'adiposity signals' that inform the brain about the mass of the adipose tissue. Basal levels of insulin and leptin are widely accepted to be adiposity signals, and...
William A Banks
William A Banks
The blood-brain barrier (BBB) is an important component of the communication network that connects the central nervous system and peripheral tissues in the control of feeding-related behaviors. Specifically, the BBB acts as an interface tha...
Timothy H Moran
Timothy H Moran
Hypothalamic neurons have the capacity to sense and alter their activity in response to fluctuations in local nutrient concentrations. Alterations in glucose, fatty acid and amino acid concentrations have all been demonstrated to affect neu...
Sebastien G Bouret
Sebastien G Bouret
The hypothalamus plays an essential role in controlling appetite during adult life. It undergoes tremendous growth beginning early in gestation and continuing during the postnatal period. During this developmental period, a variety of proce...
Wolfgang Langhans
Wolfgang Langhans
Fuel monitoring in the liver or hepatic portal area was historically implicated in the control of eating. According to this view, a common denominator of nutrient metabolism such as the intracellular ATP/ADP ratio was supposed to modulate e...
Roles of amylin in satiation, adiposity and brain development [0.03%]
人胰岛素基因产物AMYLIN在止饥、肥胖及脑发育中的作用机制研究
Thomas A Lutz
Thomas A Lutz
Amylin plays an important role in the control of nutrient fluxes. It is cosecreted with insulin and reduces eating by promoting meal-ending satiation. This effect seems to depend on a stimulation of amylin receptors in the area postrema. Su...
Bettina Wölnerhanssen,Christoph Beglinger
Bettina Wölnerhanssen
A great deal of research interest is directed toward understanding the control of appetite and regulation of metabolism. It seems as if an epidemic of obesity is sweeping the world, and type II diabetes (T2DM) is following in its wake. The ...
Wolfgang Langhans,Nori Geary
Wolfgang Langhans
Annette D De Kloet,Stephen C Woods
Annette D De Kloet
Chemoprevention of tocotrienols: the mechanism of antiproliferative effects [0.03%]
番茄红素的化学预防作用及抗增殖作用机制
Sayori Wada
Sayori Wada
Tocotrienols have been reported as antitumor agents and widely commercialized as an antioxidant dietary supplement. Tocotrienols have more significant biological activity than tocopherols, although serum level of tocotrienols is much lower ...