Michal Vostrý
Michal Vostrý
Multiplex analysis is intended to simultaneously look for multiple targets in one sample. This approach has been largely adopted in genomics and progressively expands to various domains of laboratory investigation. In protein analysis, immu...
Molecular Classification of Breast Cancer Tumours from Patients Treated with Doxorubicin and Docetaxel [0.03%]
多柔比星和多西他赛治疗患者的乳腺癌肿瘤的分子分类学
Atocha Romero Alfonso
Atocha Romero Alfonso
It is known that four main molecular breast cancer subtypes have different prognoses and different responses to therapy. Luminal A tumours have a better prognosis and they tend to be sensitive to anti-estrogen drugs. Luminal B tumours have ...
Rational Laboratory Diagnostics of Antiphospholipid Antibodies: Anti-Cardiolipin, Anti-β2-Glycoprotein I, Anti-Prothrombin and Anti-Annexin V Antibodies [0.03%]
抗磷脂抗体的合理实验室诊断:抗心脂素、抗β2糖蛋白I、抗凝血酶原和抗辅脂素V抗体
Bozic Borut,Sasa Cucnik,Natasa Gaspersic et al.
Bozic Borut et al.
A possible co-appearance of anticardiolipin (aCL), anti-β2-glycoprotein I (anti-β2-GPI), anti-prothrombin (aPT) and anti-annexin V (aANXV) antibodies of IgG, IgM and IgA class were studied in 58 patients with SLE alone and 32 patients APS...
Standardization in Clinical Enzymology - Results of a Survey Performed in 2008 in Big Hospital Laboratories in Poland [0.03%]
临床酶学中的标准化问题——基于对波兰大型医院实验室的调查结果而撰写的一篇文章(2008年)
Grazyna Sypniewska,Joanna Pollak
Grazyna Sypniewska
The survey was performed in December 2008 in 21 big hospital laboratories in Poland. The purpose of this survey was to estimate how the IFCC standardization in clinical enzymology is recognized and followed in medical laboratories. Each par...
Ilenia Infusino,Panteghini Mauro
Ilenia Infusino
The goal of standardization in Laboratory Medicine is to achieve comparable results in human samples, independent of the reagent kits, instruments, and laboratory where the assay is carried out. To pursue this objective in clinical enzymolo...
Determination of Serum Ferritin Glycosylation in Hyperferritinemia Associated to Iron Overload and Inflammation [0.03%]
铁过载和炎症相关高血清 ferritin 的糖基化测定
Bethina Isasi Gasser
Bethina Isasi Gasser
Background: Serum ferritin is a commonly used clinical biochemical parameter and hyperferritinemia is used as a surrogate marker for iron overload, acute or chronic inflammation, malignancy or cell death. The aim of the p...
The Impact of Sex and Age on Serum Prohepcidin Concentration in Healthy Adults [0.03%]
性别和年龄对健康成人血清前他莫西林浓度的影响
Joanna Jasiniewska,Ewa Zekanowska,Grazyna Dymek et al.
Joanna Jasiniewska et al.
Introduction: Within the last 8 years, it has become evident that hepcidin has a diagnostic and therapeutic potential. Therefore, it is a great need to establish the reference interval for hepcidin and its precursor. The ...
Justyna Kwapisz,Artur Slomka,Ewa Zekanowska
Justyna Kwapisz
Hepcidin, a small peptide secreted mainly by the liver, plays a central role in iron status regulation. The experiments on hepcidin seemed very promising and gave new life to understanding iron metabolism. Many authors suggest that hepcidin...
Pathogenic Mechanisms Underlying Iron Deficiency and Iron Overload: New Insights for Clinical Application [0.03%]
铁缺乏和铁过载的致病机制:临床应用的新见解
M J Kotze,D P van Velden,S J van Rensburg et al.
M J Kotze et al.
Iron uptake, utilisation, release and storage occur at the gene level. Individuals with variant forms of genes involved in iron metabolism may have different requirements for iron and are likely to respond differently to the same amount of ...
Markus Ketteler
Markus Ketteler